#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O54946 uniprotkb:Q13686 intact:EBI-642500|uniprotkb:Q3TE94|uniprotkb:Q3U6L0|uniprotkb:Q3UNJ5|uniprotkb:Q3UYT7|uniprotkb:Q99LA5|uniprotkb:Q9QYI9|ensembl:ENSMUSP00000008733 intact:EBI-13940994|ensembl:ENSP00000216489|uniprotkb:Q8TAU1|uniprotkb:Q9ULA7 psi-mi:dnjb6_mouse(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym) psi-mi:alkb1_human(display_long)|uniprotkb:ABH(gene name synonym)|uniprotkb:ABH1(gene name synonym)|uniprotkb:ALKBH(gene name synonym)|uniprotkb:ALKBH1(gene name)|psi-mi:ALKBH1(display_short)|uniprotkb:Alkylated DNA repair protein alkB homolog 1(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase ABH1(gene name synonym)|uniprotkb:DNA 6mA demethylase(gene name synonym)|uniprotkb:DNA lyase ABH1(gene name synonym)|uniprotkb:DNA oxidative demethylase ALKBH1(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH1(gene name synonym)|uniprotkb:"mRNA N(3)-methylcytidine demethylase"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Pan et al. (2008) imex:IM-25732|pubmed:18163532 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-13941029|imex:IM-25732-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033029.1|refseq:NP_001120839.1|refseq:NP_035977.2|ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000008733(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O54946|reactome:R-MMU-3371453 ensembl:ENSG00000100601(gene)|ensembl:ENST00000216489(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000791"(euchromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001890"(placenta development)|go:"GO:0002101"(tRNA wobble cytosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006281"(DNA repair)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|interpro:IPR004574(Alkylated DNA repair protein AlkB)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR027450|rcsb pdb:6IE2|rcsb pdb:6IE3|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0035552"(oxidative single-stranded DNA demethylation)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042245"(RNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048589"(developmental growth)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0103053"|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1990983"(tRNA demethylation)|go:"GO:1990984"(tRNA demethylase activity)|refseq:NP_006011.2 - - - figure legend:no fig.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/02 2017/03/02 rogid:Snii+B7COng2Zkduai/v24f83bw10090 rogid:/5jtHw+QmZSliGSwXCpOZHkMx009606 rigid:zl47w6/b762VGpKzAz9CI5zCLxk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CB42 uniprotkb:O54946-2 intact:EBI-13941048|ensembl:ENSMUSP00000124565 intact:EBI-13941040|ensembl:ENSMUSP00000110488 psi-mi:alkb1_mouse(display_long)|uniprotkb:Alkbh1(gene name)|psi-mi:Alkbh1(display_short)|uniprotkb:Abh(gene name synonym)|uniprotkb:Alkbh(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 1(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase ABH1(gene name synonym)|uniprotkb:DNA 6mA demethylase(gene name synonym)|uniprotkb:DNA lyase ABH1(gene name synonym)|uniprotkb:DNA oxidative demethylase ALKBH1(gene name synonym)|uniprotkb:tRNA N1-methyl adenine demethylase(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH1(gene name synonym)|uniprotkb:"mRNA N(3)-methylcytidine demethylase"(gene name synonym) psi-mi:o54946-2(display_long)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pan et al. (2008) imex:IM-25732|pubmed:18163532 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-13941082|imex:IM-25732-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR027450|rcsb pdb:6IMA|rcsb pdb:6IMC|rcsb pdb:6KSF|rcsb pdb:6L94|ensembl:ENSMUSG00000079036(gene)|ensembl:ENSMUST00000162961(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000791"(euchromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001890"(placenta development)|go:"GO:0002101"(tRNA wobble cytosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006281"(DNA repair)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0035552"(oxidative single-stranded DNA demethylation)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042245"(RNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048589"(developmental growth)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0103053"|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1990983"(tRNA demethylation)|go:"GO:1990984"(tRNA demethylase activity)|interpro:IPR004574(Alkylated DNA repair protein AlkB)|refseq:NP_001096035.1 ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000114839(transcript)|intact:EBI-642500(isoform-parent) - - - figure legend:6F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/03/02 2017/03/02 rogid:Vcd2SgdpmbkYeVmgtHJdYFlQ5Rw10090 rogid:5/C3E7k9hx+4kUO7kHKk5O1FuLI10090 rigid:mqsNGF4RmD5XaE5oULE+QomJ/So false myc tag:n-n xpress tag:n-n|sufficient binding region:1-210|necessary binding region:192-210 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0CB42 uniprotkb:O54946-2 intact:EBI-13941048|ensembl:ENSMUSP00000124565 intact:EBI-13941040|ensembl:ENSMUSP00000110488 psi-mi:alkb1_mouse(display_long)|uniprotkb:Alkbh1(gene name)|psi-mi:Alkbh1(display_short)|uniprotkb:Abh(gene name synonym)|uniprotkb:Alkbh(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 1(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase ABH1(gene name synonym)|uniprotkb:DNA 6mA demethylase(gene name synonym)|uniprotkb:DNA lyase ABH1(gene name synonym)|uniprotkb:DNA oxidative demethylase ALKBH1(gene name synonym)|uniprotkb:tRNA N1-methyl adenine demethylase(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH1(gene name synonym)|uniprotkb:"mRNA N(3)-methylcytidine demethylase"(gene name synonym) psi-mi:o54946-2(display_long)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pan et al. (2008) imex:IM-25732|pubmed:18163532 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-13941092|imex:IM-25732-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR027450|rcsb pdb:6IMA|rcsb pdb:6IMC|rcsb pdb:6KSF|rcsb pdb:6L94|ensembl:ENSMUSG00000079036(gene)|ensembl:ENSMUST00000162961(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000791"(euchromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001890"(placenta development)|go:"GO:0002101"(tRNA wobble cytosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006281"(DNA repair)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0035552"(oxidative single-stranded DNA demethylation)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042245"(RNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048589"(developmental growth)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0103053"|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1990983"(tRNA demethylation)|go:"GO:1990984"(tRNA demethylase activity)|interpro:IPR004574(Alkylated DNA repair protein AlkB)|refseq:NP_001096035.1 ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000114839(transcript)|intact:EBI-642500(isoform-parent) - - - figure legend:6 G/I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/03/02 2017/03/02 rogid:Vcd2SgdpmbkYeVmgtHJdYFlQ5Rw10090 rogid:5/C3E7k9hx+4kUO7kHKk5O1FuLI10090 rigid:mqsNGF4RmD5XaE5oULE+QomJ/So false myc tag:n-n|sufficient binding region:1-127 xpress tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56524 uniprotkb:O54946-2 intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606 intact:EBI-13941040|ensembl:ENSMUSP00000110488 psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym) psi-mi:o54946-2(display_long)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pan et al. (2008) imex:IM-25732|pubmed:18163532 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-13941106|imex:IM-25732-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000114839(transcript)|intact:EBI-642500(isoform-parent) - - - figure legend:6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/03/02 2017/03/02 rogid:EJhE8LikofmF9H8ubNsola4pSpc9606 rogid:5/C3E7k9hx+4kUO7kHKk5O1FuLI10090 rigid:3aVQ7rD6HDFxJDH+4Kx5Nt/4RxU false flag tag:?-? xpress tag:n-n|sufficient binding region:1-174|necessary binding region:124-174 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56524 uniprotkb:O54946-2 intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606 intact:EBI-13941040|ensembl:ENSMUSP00000110488 psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym) psi-mi:o54946-2(display_long)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pan et al. (2008) imex:IM-25732|pubmed:18163532 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-13941119|imex:IM-25732-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000114839(transcript)|intact:EBI-642500(isoform-parent) - - - figure legend:6I|antagonist:Alkbh1|comment:Association is decreasing and abolished with increasing amounts of Myc-Alkbh1 cotransfected|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/03/02 2017/03/02 rogid:EJhE8LikofmF9H8ubNsola4pSpc9606 rogid:5/C3E7k9hx+4kUO7kHKk5O1FuLI10090 rigid:3aVQ7rD6HDFxJDH+4Kx5Nt/4RxU false flag tag:?-? xpress tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)