#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P05205	uniprotkb:Q8IQ92	intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252	intact:EBI-89649|ensemblmetazoa:FBpp0076479	psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym)	psi-mi:q8iq92_drome(display_long)|uniprotkb:HP4(gene name)|psi-mi:HP4(display_short)|uniprotkb:Hip(gene name synonym)|uniprotkb:"BcDNA:GM01628"(gene name synonym)|uniprotkb:Dmel\CG8044(gene name synonym)|uniprotkb:hip(gene name synonym)|uniprotkb:Dmel_CG8044(orf name)|uniprotkb:CG8044(orf name)	psi-mi:"MI:0018"(two hybrid)	Schwendemann et al. (2008)	pubmed:18162556|doi:10.1073/pnas.0705595105|imex:IM-9039	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15677932|imex:IM-9039-3|dip:DIP-59143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA	ensemblmetazoa:FBgn0035829(gene)|ensemblmetazoa:FBtr0076764(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010369"(chromocenter)|refseq:NP_648166.2|flybase:FBgn0035829|dip:DIP-29656N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227	rogid:mfWe9yKrFqnJjM5vbGi2Uv9YpCY7227	rigid:soY9YV45VP2dNcjSl5vq/qhGb7M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05205	uniprotkb:Q8IQ92	intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252	intact:EBI-89649|ensemblmetazoa:FBpp0076479	psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym)	psi-mi:q8iq92_drome(display_long)|uniprotkb:HP4(gene name)|psi-mi:HP4(display_short)|uniprotkb:Hip(gene name synonym)|uniprotkb:"BcDNA:GM01628"(gene name synonym)|uniprotkb:Dmel\CG8044(gene name synonym)|uniprotkb:hip(gene name synonym)|uniprotkb:Dmel_CG8044(orf name)|uniprotkb:CG8044(orf name)	psi-mi:"MI:0096"(pull down)	Schwendemann et al. (2008)	pubmed:18162556|doi:10.1073/pnas.0705595105|imex:IM-9039	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15677949|imex:IM-9039-2|dip:DIP-59143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA	ensemblmetazoa:FBgn0035829(gene)|ensemblmetazoa:FBtr0076764(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010369"(chromocenter)|refseq:NP_648166.2|flybase:FBgn0035829|dip:DIP-29656N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227	rogid:mfWe9yKrFqnJjM5vbGi2Uv9YpCY7227	rigid:soY9YV45VP2dNcjSl5vq/qhGb7M	false	-	tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05205	uniprotkb:Q8IQ92	intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252	intact:EBI-89649|ensemblmetazoa:FBpp0076479	psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym)	psi-mi:q8iq92_drome(display_long)|uniprotkb:HP4(gene name)|psi-mi:HP4(display_short)|uniprotkb:Hip(gene name synonym)|uniprotkb:"BcDNA:GM01628"(gene name synonym)|uniprotkb:Dmel\CG8044(gene name synonym)|uniprotkb:hip(gene name synonym)|uniprotkb:Dmel_CG8044(orf name)|uniprotkb:CG8044(orf name)	psi-mi:"MI:0096"(pull down)	Schwendemann et al. (2008)	pubmed:18162556|doi:10.1073/pnas.0705595105|imex:IM-9039	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15677968|imex:IM-9039-1|dip:DIP-59143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA	ensemblmetazoa:FBgn0035829(gene)|ensemblmetazoa:FBtr0076764(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010369"(chromocenter)|refseq:NP_648166.2|flybase:FBgn0035829|dip:DIP-29656N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227	rogid:mfWe9yKrFqnJjM5vbGi2Uv9YpCY7227	rigid:soY9YV45VP2dNcjSl5vq/qhGb7M	false	sufficient binding region:137-206|his tag:c-c	tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)