#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32776	uniprotkb:P29083	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Di et al. (2008)	pubmed:18160537|doi:10.1073/pnas.0707892105|imex:IM-9016	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15677539|imex:IM-9016-2|dip:DIP-59125E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0465"(dip)	crc64:DAE369FE90A224F8	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606	rigid:X2BF0LUIa5+A4OSN/2C44NsUM0I	false	binding-associated region:1-115	binding-associated region:336-439	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32780	uniprotkb:P29083	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Di et al. (2008)	pubmed:18160537|doi:10.1073/pnas.0707892105|imex:IM-9016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15677560|imex:IM-9016-1|dip:DIP-59124E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606	rigid:eOEzh8AIm47bj3uqqT4V2HM6HF0	false	binding-associated region:1-127	binding-associated region:336-439	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)