#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q01718	uniprotkb:Q8TCY5	intact:EBI-9537171|uniprotkb:A8K016|uniprotkb:Q3MI45|uniprotkb:Q504X6|ensembl:ENSP00000333821	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	psi-mi:acthr_human(display_long)|uniprotkb:MC2R(gene name)|psi-mi:MC2R(display_short)|uniprotkb:ACTHR(gene name synonym)|uniprotkb:Adrenocorticotropin receptor(gene name synonym)|uniprotkb:Melanocortin receptor 2(gene name synonym)	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sebag et al. (2007)	pubmed:18077336|doi:10.1073/pnas.0708916105|imex:IM-9242	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15675612|imex:IM-9242-3|dip:DIP-59460E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016881270.1|refseq:NP_001278840.1|refseq:NP_000520.1|dip:DIP-29949N|ensembl:ENSG00000185231(gene)|ensembl:ENST00000327606(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004978"(corticotropin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001168("Adrenocorticotrophin (ACTH) receptor")|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-5579031|reactome:R-HSA-9660821	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/05	2017/08/10	rogid:8ws6S3uX+iCrWkXmZ05MErv+FSI9606	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rigid:T7fBdvpe/w//nDkyBEpXoQguCcM	false	ha tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q01718	uniprotkb:Q8TCY5	intact:EBI-9537171|uniprotkb:A8K016|uniprotkb:Q3MI45|uniprotkb:Q504X6|ensembl:ENSP00000333821	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	psi-mi:acthr_human(display_long)|uniprotkb:MC2R(gene name)|psi-mi:MC2R(display_short)|uniprotkb:ACTHR(gene name synonym)|uniprotkb:Adrenocorticotropin receptor(gene name synonym)|uniprotkb:Melanocortin receptor 2(gene name synonym)	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sebag et al. (2007)	pubmed:18077336|doi:10.1073/pnas.0708916105|imex:IM-9242	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15675633|imex:IM-9242-1|dip:DIP-59460E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016881270.1|refseq:NP_001278840.1|refseq:NP_000520.1|dip:DIP-29949N|ensembl:ENSG00000185231(gene)|ensembl:ENST00000327606(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004978"(corticotropin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001168("Adrenocorticotrophin (ACTH) receptor")|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-5579031|reactome:R-HSA-9660821	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/05	2017/08/10	rogid:8ws6S3uX+iCrWkXmZ05MErv+FSI9606	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rigid:T7fBdvpe/w//nDkyBEpXoQguCcM	false	ha tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8TCY5	uniprotkb:Q8TCY5	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sebag et al. (2007)	pubmed:18077336|doi:10.1073/pnas.0708916105|imex:IM-9242	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15675654|imex:IM-9242-2|dip:DIP-59461E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/05	2017/08/10	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rigid:9P6ncPUWzfSkbfIiXP0OHZfXXeA	false	flag tag:c-c	v5 tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)