#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O18734 uniprotkb:O14974 intact:EBI-15674919|ensembl:ENSSSCP00045003096|ensembl:ENSSSCP00050025706|ensembl:ENSSSCP00055049345|ensembl:ENSSSCP00060020207|ensembl:ENSSSCP00065021110|ensembl:ENSSSCP00070011901|ensembl:ENSSSCP00025001174|ensembl:ENSSSCP00030036012|ensembl:ENSSSCP00035018596|ensembl:ENSSSCP00040033383|uniprotkb:Q9TQZ8|uniprotkb:Q9TQZ9|uniprotkb:Q9TR00|uniprotkb:Q9TR01|uniprotkb:Q9TR02 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 psi-mi:pp14a_pig(display_long)|uniprotkb:CPI17(gene name)|psi-mi:CPI17(display_short)|uniprotkb:17 kDa PKC-potentiated inhibitory protein of PP1(gene name synonym)|uniprotkb:Protein kinase C-potentiated inhibitor protein of 17 kDa(gene name synonym) psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Eto et al. (2007) pubmed:18073109|doi:10.1016/j.str.2007.10.014|imex:IM-14175 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15674946|imex:IM-14175-1|dip:DIP-102891E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSSSCG00025002455(gene)|ensembl:ENSSSCG00030056455(gene)|ensembl:ENSSSCG00035035095(gene)|ensembl:ENSSSCG00040057186(gene)|ensembl:ENSSSCG00045002943(gene)|ensembl:ENSSSCG00050043939(gene)|ensembl:ENSSSCG00055030798(gene)|ensembl:ENSSSCG00060034795(gene)|ensembl:ENSSSCT00025003191(transcript)|ensembl:ENSSSCT00030078693(transcript)|ensembl:ENSSSCT00035046521(transcript)|ensembl:ENSSSCT00040077589(transcript)|ensembl:ENSSSCT00045004740(transcript)|ensembl:ENSSSCT00050059824(transcript)|ensembl:ENSSSCT00055061484(transcript)|ensembl:ENSSSCT00060047176(transcript)|ensembl:ENSSSCT00065048846(transcript)|ensembl:ENSSSCT00070014421(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|ensembl:ENSSSCG00065035831(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042325"(regulation of phosphorylation)|interpro:IPR008025(PKC-activated phosphatase-1 inhibitor)|interpro:IPR036658|rcsb pdb:1J2M|rcsb pdb:1J2N|rcsb pdb:1K5O|rcsb pdb:2RLT|ensembl:ENSSSCG00070007478(gene)|refseq:NP_999502.1|dip:DIP-48426N refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:vGkTTb/cWPIlRQXk0ofLoa1+aL49823 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rigid:MDPMaxYNIIb81Slk/OfMmsOxrtA false - binding-associated region:1-19 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O18734 uniprotkb:O14974 intact:EBI-15674919|ensembl:ENSSSCP00045003096|ensembl:ENSSSCP00050025706|ensembl:ENSSSCP00055049345|ensembl:ENSSSCP00060020207|ensembl:ENSSSCP00065021110|ensembl:ENSSSCP00070011901|ensembl:ENSSSCP00025001174|ensembl:ENSSSCP00030036012|ensembl:ENSSSCP00035018596|ensembl:ENSSSCP00040033383|uniprotkb:Q9TQZ8|uniprotkb:Q9TQZ9|uniprotkb:Q9TR00|uniprotkb:Q9TR01|uniprotkb:Q9TR02 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 psi-mi:pp14a_pig(display_long)|uniprotkb:CPI17(gene name)|psi-mi:CPI17(display_short)|uniprotkb:17 kDa PKC-potentiated inhibitory protein of PP1(gene name synonym)|uniprotkb:Protein kinase C-potentiated inhibitor protein of 17 kDa(gene name synonym) psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Eto et al. (2007) pubmed:18073109|doi:10.1016/j.str.2007.10.014|imex:IM-14175 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15674966|imex:IM-14175-2|dip:DIP-102891E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSSSCG00025002455(gene)|ensembl:ENSSSCG00030056455(gene)|ensembl:ENSSSCG00035035095(gene)|ensembl:ENSSSCG00040057186(gene)|ensembl:ENSSSCG00045002943(gene)|ensembl:ENSSSCG00050043939(gene)|ensembl:ENSSSCG00055030798(gene)|ensembl:ENSSSCG00060034795(gene)|ensembl:ENSSSCT00025003191(transcript)|ensembl:ENSSSCT00030078693(transcript)|ensembl:ENSSSCT00035046521(transcript)|ensembl:ENSSSCT00040077589(transcript)|ensembl:ENSSSCT00045004740(transcript)|ensembl:ENSSSCT00050059824(transcript)|ensembl:ENSSSCT00055061484(transcript)|ensembl:ENSSSCT00060047176(transcript)|ensembl:ENSSSCT00065048846(transcript)|ensembl:ENSSSCT00070014421(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|ensembl:ENSSSCG00065035831(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042325"(regulation of phosphorylation)|interpro:IPR008025(PKC-activated phosphatase-1 inhibitor)|interpro:IPR036658|rcsb pdb:1J2M|rcsb pdb:1J2N|rcsb pdb:1K5O|rcsb pdb:2RLT|ensembl:ENSSSCG00070007478(gene)|refseq:NP_999502.1|dip:DIP-48426N refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2018/12/11 rogid:vGkTTb/cWPIlRQXk0ofLoa1+aL49823 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rigid:MDPMaxYNIIb81Slk/OfMmsOxrtA false - sufficient binding region:1-300|myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)