#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BH43 uniprotkb:Q8CBW3 intact:EBI-643162|ensembl:ENSMUSP00000081263|ensembl:ENSMUSP00000101532 intact:EBI-375511|uniprotkb:Q3U8V0|uniprotkb:Q60747|uniprotkb:Q91ZM5|uniprotkb:Q923I9|uniprotkb:Q99KH4|ensembl:ENSMUSP00000118491 psi-mi:wasf2_mouse(display_long)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Wave2(gene name synonym)|uniprotkb:Wasf2(gene name)|psi-mi:Wasf2(display_short) psi-mi:abi1_mouse(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short)|uniprotkb:Ssh3bp1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Ablphilin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2007) pubmed:18044991|doi:10.1371/journal.pbio.0050317|imex:IM-8833 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15672821|imex:IM-8833-2|dip:DIP-58957E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_700472.1|refseq:XP_006538911.1|refseq:XP_006538912.1|refseq:XP_006538913.1|ensembl:ENSMUSG00000028868(gene)|ensembl:ENSMUST00000084241(transcript)|ensembl:ENSMUST00000105912(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q8BH43|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|dip:DIP-29535N refseq:NP_031406.2|refseq:NP_001070658.1|refseq:NP_001070660.1|refseq:NP_001070661.1|ensembl:ENSMUSG00000058835(gene)|ensembl:ENSMUST00000123948(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043005"(neuron projection)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8CBW3|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|dip:DIP-29534N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:uXkOyyt8x6/M/EU/uhIp8/BAc9w10090 rogid:mDXRmY9uUy6POYZDWeVlwDPxAIs10090 rigid:A6/9btFcRwPoGPXvsgiPTUmHOYY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CBW3 uniprotkb:Q9Z207 intact:EBI-375511|uniprotkb:Q3U8V0|uniprotkb:Q60747|uniprotkb:Q91ZM5|uniprotkb:Q923I9|uniprotkb:Q99KH4|ensembl:ENSMUSP00000118491 intact:EBI-6550123|ensembl:ENSMUSP00000129420 psi-mi:abi1_mouse(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short)|uniprotkb:Ssh3bp1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Ablphilin-1(gene name synonym) psi-mi:diap3_mouse(display_long)|uniprotkb:Diaph3(gene name)|psi-mi:Diaph3(display_short)|uniprotkb:Diap3(gene name synonym)|uniprotkb:Diaphanous-related formin-3(gene name synonym)|uniprotkb:p134mDIA2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2007) pubmed:18044991|doi:10.1371/journal.pbio.0050317|imex:IM-8833 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15672838|imex:IM-8833-1|dip:DIP-58956E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031406.2|refseq:NP_001070658.1|refseq:NP_001070660.1|refseq:NP_001070661.1|ensembl:ENSMUSG00000058835(gene)|ensembl:ENSMUST00000123948(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043005"(neuron projection)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8CBW3|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|dip:DIP-29534N ensembl:ENSMUSG00000022021(gene)|ensembl:ENSMUST00000168889(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027654|interpro:IPR042201|mint:Q9Z207|reactome:R-MMU-5663220|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_062644.1|dip:DIP-29533N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:mDXRmY9uUy6POYZDWeVlwDPxAIs10090 rogid:zvX/aYKjtR5pkxYjfJVbBS2tUlU10090 rigid:RMfWiigKFQqiZ73BAx5pFhpyiVQ false - green fluorescent protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CBW3 uniprotkb:Q9Z207 intact:EBI-375511|uniprotkb:Q3U8V0|uniprotkb:Q60747|uniprotkb:Q91ZM5|uniprotkb:Q923I9|uniprotkb:Q99KH4|ensembl:ENSMUSP00000118491 intact:EBI-6550123|ensembl:ENSMUSP00000129420 psi-mi:abi1_mouse(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short)|uniprotkb:Ssh3bp1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Ablphilin-1(gene name synonym) psi-mi:diap3_mouse(display_long)|uniprotkb:Diaph3(gene name)|psi-mi:Diaph3(display_short)|uniprotkb:Diap3(gene name synonym)|uniprotkb:Diaphanous-related formin-3(gene name synonym)|uniprotkb:p134mDIA2(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2007) pubmed:18044991|doi:10.1371/journal.pbio.0050317|imex:IM-8833 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15672857|imex:IM-8833-3|dip:DIP-58956E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031406.2|refseq:NP_001070658.1|refseq:NP_001070660.1|refseq:NP_001070661.1|ensembl:ENSMUSG00000058835(gene)|ensembl:ENSMUST00000123948(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043005"(neuron projection)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8CBW3|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|dip:DIP-29534N ensembl:ENSMUSG00000022021(gene)|ensembl:ENSMUST00000168889(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027654|interpro:IPR042201|mint:Q9Z207|reactome:R-MMU-5663220|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_062644.1|dip:DIP-29533N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mDXRmY9uUy6POYZDWeVlwDPxAIs10090 rogid:zvX/aYKjtR5pkxYjfJVbBS2tUlU10090 rigid:RMfWiigKFQqiZ73BAx5pFhpyiVQ false sufficient binding region:419-478|tag:n-n sufficient binding region:1-550|green fluorescent protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)