#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21784 intact:EBI-15671342 intact:EBI-7602123|intact:MINT-8384500|ensembl:ENSMUSP00000038204|ensembl:ENSMUSP00000106858 dip:DIP-46178N psi-mi:rag2_mouse(display_long)|uniprotkb:Rag2(gene name)|psi-mi:Rag2(display_short)|uniprotkb:Rag-2(gene name synonym) psi-mi:"h3 (1)"(display_short)|psi-mi:EBI-15671342(display_long) psi-mi:"MI:0114"(x-ray crystallography) Ramón-Maiques et al. (2007) pubmed:18025461|doi:10.1073/pnas.0709170104|imex:IM-9425 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15671345|imex:IM-9425-1|dip:DIP-88016E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017172095.1|refseq:NP_033046.1|ensembl:ENSMUSG00000032864(gene)|ensembl:ENSMUST00000044031(transcript)|ensembl:ENSMUST00000111227(transcript)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097519"(DNA recombinase complex)|interpro:IPR004321(V-D-J recombination activating protein 2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR025162|rcsb pdb:2JWO|rcsb pdb:2V83|rcsb pdb:2V85|rcsb pdb:2V86|rcsb pdb:2V87|rcsb pdb:2V88|rcsb pdb:2V89|rcsb pdb:4WWX|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEP|rcsb pdb:6OEQ|rcsb pdb:6OER|rcsb pdb:6OES|rcsb pdb:6OET|rcsb pdb:6V0V|rcsb pdb:6XNX|rcsb pdb:6XNY|rcsb pdb:6XNZ|rcsb pdb:6OEO|dip:DIP-46179N - psi-mi:"MI:0465"(dip) comment:mint|comment:homomint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:YNZD3oEaJR86dm4pNKPl4Qu+N5g10090 rogid:JYaAp/aolUtUB+ojQVC4M0S7L+Y-2 rigid:49bsQyYeC5pqszlVtyhS60A7jgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21784 intact:EBI-15671366 intact:EBI-7602123|intact:MINT-8384500|ensembl:ENSMUSP00000038204|ensembl:ENSMUSP00000106858 dip:DIP-46180N psi-mi:rag2_mouse(display_long)|uniprotkb:Rag2(gene name)|psi-mi:Rag2(display_short)|uniprotkb:Rag-2(gene name synonym) psi-mi:"h3 (2)"(display_short)|psi-mi:EBI-15671366(display_long) psi-mi:"MI:0114"(x-ray crystallography) Ramón-Maiques et al. (2007) pubmed:18025461|doi:10.1073/pnas.0709170104|imex:IM-9425 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15671369|imex:IM-9425-2|dip:DIP-88017E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017172095.1|refseq:NP_033046.1|ensembl:ENSMUSG00000032864(gene)|ensembl:ENSMUST00000044031(transcript)|ensembl:ENSMUST00000111227(transcript)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097519"(DNA recombinase complex)|interpro:IPR004321(V-D-J recombination activating protein 2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR025162|rcsb pdb:2JWO|rcsb pdb:2V83|rcsb pdb:2V85|rcsb pdb:2V86|rcsb pdb:2V87|rcsb pdb:2V88|rcsb pdb:2V89|rcsb pdb:4WWX|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEP|rcsb pdb:6OEQ|rcsb pdb:6OER|rcsb pdb:6OES|rcsb pdb:6OET|rcsb pdb:6V0V|rcsb pdb:6XNX|rcsb pdb:6XNY|rcsb pdb:6XNZ|rcsb pdb:6OEO|dip:DIP-46179N - psi-mi:"MI:0465"(dip) comment:mint|comment:homomint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:YNZD3oEaJR86dm4pNKPl4Qu+N5g10090 rogid:j+Vs6hl6rR++ybJ2qjUPaG8Fldk-2 rigid:rnA5ACdWPG1gQRUsb5LvrvnkexY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21784 intact:EBI-15671342 intact:EBI-7602123|intact:MINT-8384500|ensembl:ENSMUSP00000038204|ensembl:ENSMUSP00000106858 dip:DIP-46178N psi-mi:rag2_mouse(display_long)|uniprotkb:Rag2(gene name)|psi-mi:Rag2(display_short)|uniprotkb:Rag-2(gene name synonym) psi-mi:"h3 (1)"(display_short)|psi-mi:EBI-15671342(display_long) psi-mi:"MI:0096"(pull down) Ramón-Maiques et al. (2007) pubmed:18025461|doi:10.1073/pnas.0709170104|imex:IM-9425 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15671386|imex:IM-9425-3|dip:DIP-88016E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017172095.1|refseq:NP_033046.1|ensembl:ENSMUSG00000032864(gene)|ensembl:ENSMUST00000044031(transcript)|ensembl:ENSMUST00000111227(transcript)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097519"(DNA recombinase complex)|interpro:IPR004321(V-D-J recombination activating protein 2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR025162|rcsb pdb:2JWO|rcsb pdb:2V83|rcsb pdb:2V85|rcsb pdb:2V86|rcsb pdb:2V87|rcsb pdb:2V88|rcsb pdb:2V89|rcsb pdb:4WWX|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEP|rcsb pdb:6OEQ|rcsb pdb:6OER|rcsb pdb:6OES|rcsb pdb:6OET|rcsb pdb:6V0V|rcsb pdb:6XNX|rcsb pdb:6XNY|rcsb pdb:6XNZ|rcsb pdb:6OEO|dip:DIP-46179N - psi-mi:"MI:0465"(dip) comment:mint|comment:homomint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:YNZD3oEaJR86dm4pNKPl4Qu+N5g10090 rogid:JYaAp/aolUtUB+ojQVC4M0S7L+Y-2 rigid:49bsQyYeC5pqszlVtyhS60A7jgc false mutation disrupting interaction strength:415-415,443-443,453-453|sufficient binding region:414-527|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)