#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14719 uniprotkb:Q61730 intact:EBI-525078|uniprotkb:Q05208|ensembl:ENSMUSP00000054914|ensembl:ENSMUSP00000095379 intact:EBI-525035|uniprotkb:Q8VCB9|uniprotkb:Q3UVZ1|ensembl:ENSMUSP00000023156 psi-mi:ilrl1_mouse(display_long)|uniprotkb:Protein ST2(gene name synonym)|uniprotkb:Protein T1(gene name synonym)|uniprotkb:Lymphocyte antigen 84(gene name synonym)|uniprotkb:Il1rl1(gene name)|psi-mi:Il1rl1(display_short)|uniprotkb:Ly84(gene name synonym)|uniprotkb:St2(gene name synonym)|uniprotkb:Ste2(gene name synonym)|uniprotkb:Interleukin-33 receptor alpha chain(gene name synonym) psi-mi:il1ap_mouse(display_long)|uniprotkb:Il1rap(gene name)|psi-mi:Il1rap(display_short)|uniprotkb:Interleukin-33 receptot beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ali et al. (2007) pubmed:18003919|doi:10.1073/pnas.0705939104|imex:IM-9436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15670752|imex:IM-9436-1|dip:DIP-88028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020773.1|refseq:NP_034873.2|refseq:NP_001281100.1|refseq:XP_006495804.1|refseq:XP_006495807.1|ensembl:ENSMUSG00000026069(gene)|ensembl:ENSMUST00000053043(transcript)|ensembl:ENSMUST00000097772(transcript)|go:"GO:0002113"(interleukin-33 binding)|go:"GO:0002114"(interleukin-33 receptor activity)|go:"GO:0002826"(negative regulation of T-helper 1 type immune response)|go:"GO:0004908"(interleukin-1 receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004074(Interleukin-1 receptor, type I and type II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5VI4|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9014843|go:"GO:0032722"(positive regulation of chemokine production)|refseq:XP_017174571.1|dip:DIP-34958N refseq:NP_032390.1|refseq:NP_598864.1|refseq:NP_001152790.1|ensembl:ENSMUSG00000022514(gene)|ensembl:ENSMUST00000023156(transcript)|go:"GO:0002114"(interleukin-33 receptor activity)|go:"GO:0004908"(interleukin-1 receptor activity)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038172"(interleukin-33-mediated signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004074(Interleukin-1 receptor, type I and type II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR035897|interpro:IPR036179|interpro:IPR041416|rcsb pdb:4YFD|rcsb pdb:5VI4|reactome:R-MMU-1257604|reactome:R-MMU-388844|reactome:R-MMU-6811558|reactome:R-MMU-9014826|reactome:R-MMU-9014843|reactome:R-MMU-9020702|dip:DIP-296N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:GPD5Bm6L00WnwYKuwUBCxlY7zQw10090 rogid:t6go1Z8XGGOANmCmvimPb/wwc2g10090 rigid:0A3aYQVa6tRYdPNiegWq4S9bvCM false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P14719 uniprotkb:Q61730 intact:EBI-525078|uniprotkb:Q05208|ensembl:ENSMUSP00000054914|ensembl:ENSMUSP00000095379 intact:EBI-525035|uniprotkb:Q8VCB9|uniprotkb:Q3UVZ1|ensembl:ENSMUSP00000023156 psi-mi:ilrl1_mouse(display_long)|uniprotkb:Protein ST2(gene name synonym)|uniprotkb:Protein T1(gene name synonym)|uniprotkb:Lymphocyte antigen 84(gene name synonym)|uniprotkb:Il1rl1(gene name)|psi-mi:Il1rl1(display_short)|uniprotkb:Ly84(gene name synonym)|uniprotkb:St2(gene name synonym)|uniprotkb:Ste2(gene name synonym)|uniprotkb:Interleukin-33 receptor alpha chain(gene name synonym) psi-mi:il1ap_mouse(display_long)|uniprotkb:Il1rap(gene name)|psi-mi:Il1rap(display_short)|uniprotkb:Interleukin-33 receptot beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ali et al. (2007) pubmed:18003919|doi:10.1073/pnas.0705939104|imex:IM-9436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15670773|imex:IM-9436-2|dip:DIP-88028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020773.1|refseq:NP_034873.2|refseq:NP_001281100.1|refseq:XP_006495804.1|refseq:XP_006495807.1|ensembl:ENSMUSG00000026069(gene)|ensembl:ENSMUST00000053043(transcript)|ensembl:ENSMUST00000097772(transcript)|go:"GO:0002113"(interleukin-33 binding)|go:"GO:0002114"(interleukin-33 receptor activity)|go:"GO:0002826"(negative regulation of T-helper 1 type immune response)|go:"GO:0004908"(interleukin-1 receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004074(Interleukin-1 receptor, type I and type II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5VI4|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9014843|go:"GO:0032722"(positive regulation of chemokine production)|refseq:XP_017174571.1|dip:DIP-34958N refseq:NP_032390.1|refseq:NP_598864.1|refseq:NP_001152790.1|ensembl:ENSMUSG00000022514(gene)|ensembl:ENSMUST00000023156(transcript)|go:"GO:0002114"(interleukin-33 receptor activity)|go:"GO:0004908"(interleukin-1 receptor activity)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038172"(interleukin-33-mediated signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004074(Interleukin-1 receptor, type I and type II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR035897|interpro:IPR036179|interpro:IPR041416|rcsb pdb:4YFD|rcsb pdb:5VI4|reactome:R-MMU-1257604|reactome:R-MMU-388844|reactome:R-MMU-6811558|reactome:R-MMU-9014826|reactome:R-MMU-9014843|reactome:R-MMU-9020702|dip:DIP-296N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:GPD5Bm6L00WnwYKuwUBCxlY7zQw10090 rogid:t6go1Z8XGGOANmCmvimPb/wwc2g10090 rigid:0A3aYQVa6tRYdPNiegWq4S9bvCM false fusion protein:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)