#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q97Z79 uniprotkb:Q97W59 intact:EBI-9010365|ensemblbacteria:AAK41314 intact:EBI-9010350|ensemblbacteria:AAK42529 psi-mi:if2a_sacs2(display_long)|uniprotkb:eif2a(gene name)|psi-mi:eif2a(display_short)|uniprotkb:aIF2-alpha(gene name synonym)|uniprotkb:aif2a(gene name synonym)|uniprotkb:eIF-2-alpha(gene name synonym)|uniprotkb:SSO1050(locus name) psi-mi:if2b_sacs2(display_long)|uniprotkb:eif2b(gene name)|psi-mi:eif2b(display_short)|uniprotkb:aIF2-beta(gene name synonym)|uniprotkb:aif2b(gene name synonym)|uniprotkb:eIF-2-beta(gene name synonym)|uniprotkb:SSO2381(locus name) psi-mi:"MI:0114"(x-ray crystallography) Yatime et al. (2007) pubmed:18000047|doi:10.1073/pnas.0706784104|imex:IM-9430 taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15670313|imex:IM-9430-1|dip:DIP-88022E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_009989173.1|dip:DIP-29030N|interpro:IPR024055|interpro:IPR044126|rcsb pdb:2AHO|rcsb pdb:2QMU|rcsb pdb:2QN6|rcsb pdb:3CW2|rcsb pdb:3QSY|rcsb pdb:3V11|rcsb pdb:5JB3|rcsb pdb:5JBH|rcsb pdb:6SW9|rcsb pdb:6SWC|ensemblbacteria:AAK41314(transcript)|ensemblbacteria:SSO1050(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022964|interpro:IPR022967|interpro:IPR024054 refseq:WP_009989461.1|dip:DIP-46185N|ensemblbacteria:AAK42529(transcript)|ensemblbacteria:SSO2381(gene)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR004458(Archaeal translation initiation factor aIF-2, beta subunit)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:2NXU|rcsb pdb:2QMU|rcsb pdb:2QN6|rcsb pdb:3CW2|rcsb pdb:3V11|rcsb pdb:5JB3|rcsb pdb:5JBH|rcsb pdb:5K0Y|rcsb pdb:6SW9|rcsb pdb:6SWC psi-mi:"MI:0465"(dip) crc64:A94E66BBE2931272 crc64:A5C60230FDAE921C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:8HX5lqiIRv6BmL8uVYV8FYMrFgQ273057 rogid:X6KJ2arH0Ul8kWY3hqlS0iIz2R0273057 rigid:QnMrR52hobH6y/v0WwQxLTUZCWM false binding-associated region:175-265 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q97Z79 uniprotkb:Q980A5 intact:EBI-9010365|ensemblbacteria:AAK41314 intact:EBI-9010337|ensemblbacteria:AAK40740 psi-mi:if2a_sacs2(display_long)|uniprotkb:eif2a(gene name)|psi-mi:eif2a(display_short)|uniprotkb:aIF2-alpha(gene name synonym)|uniprotkb:aif2a(gene name synonym)|uniprotkb:eIF-2-alpha(gene name synonym)|uniprotkb:SSO1050(locus name) psi-mi:if2g_sacs2(display_long)|uniprotkb:eif2g(gene name)|psi-mi:eif2g(display_short)|uniprotkb:aIF2-gamma(gene name synonym)|uniprotkb:eIF-2-gamma(gene name synonym)|uniprotkb:SSO0412(locus name) psi-mi:"MI:0114"(x-ray crystallography) Yatime et al. (2007) pubmed:18000047|doi:10.1073/pnas.0706784104|imex:IM-9430 taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15670313|imex:IM-9430-1|dip:DIP-88022E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_009989173.1|dip:DIP-29030N|interpro:IPR024055|interpro:IPR044126|rcsb pdb:2AHO|rcsb pdb:2QMU|rcsb pdb:2QN6|rcsb pdb:3CW2|rcsb pdb:3QSY|rcsb pdb:3V11|rcsb pdb:5JB3|rcsb pdb:5JBH|rcsb pdb:6SW9|rcsb pdb:6SWC|ensemblbacteria:AAK41314(transcript)|ensemblbacteria:SSO1050(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022964|interpro:IPR022967|interpro:IPR024054 refseq:WP_009988771.1|dip:DIP-29031N|ensemblbacteria:AAK40740(transcript)|ensemblbacteria:SSO0412(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR022424|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:2AHO|rcsb pdb:2PLF|rcsb pdb:2PMD|rcsb pdb:2QMU|rcsb pdb:2QN6|rcsb pdb:3CW2|rcsb pdb:3I1F|rcsb pdb:3PEN|rcsb pdb:3QSY|rcsb pdb:3SJZ|rcsb pdb:3V11|rcsb pdb:4M0L|rcsb pdb:4M2L|rcsb pdb:4M4S|rcsb pdb:4M53|rcsb pdb:4NBS|rcsb pdb:4QFM|rcsb pdb:4QHY|rcsb pdb:4RCY|rcsb pdb:4RCZ|rcsb pdb:4RD0|rcsb pdb:4RD1|rcsb pdb:4RD2|rcsb pdb:4RD3|rcsb pdb:4RD4|rcsb pdb:4RD6|rcsb pdb:4RJL|rcsb pdb:5DSZ|rcsb pdb:5JB3|rcsb pdb:5JBH|rcsb pdb:6H6K|rcsb pdb:6I5M|rcsb pdb:6R8S|rcsb pdb:6R8T|rcsb pdb:6SW9|rcsb pdb:6SWC|go:"GO:0001731"(formation of translation preinitiation complex) psi-mi:"MI:0465"(dip) crc64:A94E66BBE2931272 crc64:74A1F3C850D2D3D2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:8HX5lqiIRv6BmL8uVYV8FYMrFgQ273057 rogid:rytaFMHRaMYLRy8Nhcd2b2F4gag273057 rigid:QnMrR52hobH6y/v0WwQxLTUZCWM false binding-associated region:175-265 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)