#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36130 uniprotkb:P40515 intact:EBI-26394|uniprotkb:D6VX99|ensemblfungi:YKR036C intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C psi-mi:caf4_yeast(display_long)|uniprotkb:YKR036C(locus name)|uniprotkb:CAF4(gene name)|psi-mi:CAF4(display_short) psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:"MI:0071"(molecular sieving) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15669887|imex:IM-9427-1|dip:DIP-88018E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012962.3|sgd:S000001744|mint:P36130|dip:DIP-5945N|ensemblfungi:YKR036C(gene)|ensemblfungi:YKR036C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021653|interpro:IPR036322|rcsb pdb:2PQR sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX psi-mi:"MI:0465"(dip) crc64:2C6B472CCC2340D3 crc64:BD62D19524770536 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:vszAMkJRFSZe1PGavlyTsfEcvkI559292 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rigid:wL9IEDNclbSl88JsPAdInqMEt5o false binding-associated region:81-140 binding-associated region:1-129 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40515 uniprotkb:P47025 intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15669908|imex:IM-9427-2|dip:DIP-18246E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST psi-mi:"MI:0465"(dip) crc64:BD62D19524770536 crc64:CA8A23DBB06193A6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:3qqyPaabVmIaH7E/GDhmZXi+R18 false binding-associated region:1-129 binding-associated region:122-171 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36130 uniprotkb:P40515 intact:EBI-26394|uniprotkb:D6VX99|ensemblfungi:YKR036C intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C psi-mi:caf4_yeast(display_long)|uniprotkb:YKR036C(locus name)|uniprotkb:CAF4(gene name)|psi-mi:CAF4(display_short) psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15669998|imex:IM-9427-5|dip:DIP-88018E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012962.3|sgd:S000001744|mint:P36130|dip:DIP-5945N|ensemblfungi:YKR036C(gene)|ensemblfungi:YKR036C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021653|interpro:IPR036322|rcsb pdb:2PQR sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX psi-mi:"MI:0465"(dip) crc64:2C6B472CCC2340D3 crc64:BD62D19524770536 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vszAMkJRFSZe1PGavlyTsfEcvkI559292 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rigid:wL9IEDNclbSl88JsPAdInqMEt5o false mutation disrupting interaction strength:110-110|mutation disrupting interaction strength:111-111|mutation disrupting interaction strength:114-114|mutation disrupting interaction strength:85-86|mutation disrupting interaction strength:88-88|ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36130 uniprotkb:P40515 intact:EBI-26394|uniprotkb:D6VX99|ensemblfungi:YKR036C intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C psi-mi:caf4_yeast(display_long)|uniprotkb:YKR036C(locus name)|uniprotkb:CAF4(gene name)|psi-mi:CAF4(display_short) psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15670030|imex:IM-9427-6|dip:DIP-88018E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012962.3|sgd:S000001744|mint:P36130|dip:DIP-5945N|ensemblfungi:YKR036C(gene)|ensemblfungi:YKR036C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021653|interpro:IPR036322|rcsb pdb:2PQR sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX psi-mi:"MI:0465"(dip) crc64:2C6B472CCC2340D3 crc64:BD62D19524770536 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:vszAMkJRFSZe1PGavlyTsfEcvkI559292 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rigid:wL9IEDNclbSl88JsPAdInqMEt5o false binding-associated region:81-140 binding-associated region:1-129 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40515 uniprotkb:P47025 intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15670052|imex:IM-9427-7|dip:DIP-18246E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST psi-mi:"MI:0465"(dip) crc64:BD62D19524770536 crc64:CA8A23DBB06193A6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:3qqyPaabVmIaH7E/GDhmZXi+R18 false binding-associated region:1-129 binding-associated region:122-171 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40515 uniprotkb:P47025 intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15669977|imex:IM-9427-4|dip:DIP-18246E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST psi-mi:"MI:0465"(dip) crc64:BD62D19524770536 crc64:CA8A23DBB06193A6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:3qqyPaabVmIaH7E/GDhmZXi+R18 false binding-associated region:1-127 sufficient binding region:88-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40515 uniprotkb:P47025 intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15669929|imex:IM-9427-3|dip:DIP-18246E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST psi-mi:"MI:0465"(dip) crc64:BD62D19524770536 crc64:CA8A23DBB06193A6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:3qqyPaabVmIaH7E/GDhmZXi+R18 false mutation disrupting interaction:44-44,43-43|mutation disrupting interaction:47-47|mutation disrupting interaction:25-25,24-24|myc tag:n-n mutation disrupting interaction:148-148|mutation disrupting interaction:149-149|mutation disrupting interaction:152-152|mutation disrupting interaction:99-99,100-100|mutation disrupting interaction:105-105|ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36130 uniprotkb:P40515 intact:EBI-26394|uniprotkb:D6VX99|ensemblfungi:YKR036C intact:EBI-25059|uniprotkb:D6VVL9|ensemblfungi:YIL065C psi-mi:caf4_yeast(display_long)|uniprotkb:YKR036C(locus name)|uniprotkb:CAF4(gene name)|psi-mi:CAF4(display_short) psi-mi:fis1_yeast(display_long)|uniprotkb:Mitochondrial division protein 2(gene name synonym)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:MDV2(gene name synonym)|uniprotkb:YIL065C(locus name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2007) pubmed:17998537|doi:10.1073/pnas.0706441104|imex:IM-9427 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15670073|imex:IM-9427-8|dip:DIP-88018E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012962.3|sgd:S000001744|mint:P36130|dip:DIP-5945N|ensemblfungi:YKR036C(gene)|ensemblfungi:YKR036C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021653|interpro:IPR036322|rcsb pdb:2PQR sgd:S000001327|refseq:NP_012199.3|dip:DIP-1897N|reactome:R-SCE-9603798|ensemblfungi:YIL065C(gene)|ensemblfungi:YIL065C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|rcsb pdb:1Y8M|rcsb pdb:2PQN|rcsb pdb:2PQR|rcsb pdb:3O48|rcsb pdb:3UUX psi-mi:"MI:0465"(dip) crc64:2C6B472CCC2340D3 crc64:BD62D19524770536 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vszAMkJRFSZe1PGavlyTsfEcvkI559292 rogid:KRkQNanb9iSJ1rp+wV+XN4FqZDE559292 rigid:wL9IEDNclbSl88JsPAdInqMEt5o false sufficient binding region:90-142 binding-associated region:1-127 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)