#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00642 uniprotkb:P00642 intact:EBI-15669324 intact:EBI-15669324 psi-mi:t2e1_ecolx(display_long)|uniprotkb:ecoRIR(gene name)|psi-mi:ecoRIR(display_short)|uniprotkb:Endonuclease EcoRI(gene name synonym)|uniprotkb:Type II restriction enzyme EcoRI(gene name synonym) psi-mi:t2e1_ecolx(display_long)|uniprotkb:ecoRIR(gene name)|psi-mi:ecoRIR(display_short)|uniprotkb:Endonuclease EcoRI(gene name synonym)|uniprotkb:Type II restriction enzyme EcoRI(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Sapienza et al. (2007) pubmed:17997963|doi:10.1016/j.str.2007.09.014|imex:IM-8822 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15669349|imex:IM-8822-1|dip:DIP-18594E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0009036"(type II site-specific deoxyribonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|interpro:IPR004221(Restriction endonuclease, type II, EcoRI)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011336(Restriction endonuclease, type II, EcoRi/MunI, core)|interpro:IPR018131|rcsb pdb:1CKQ|rcsb pdb:1CL8|rcsb pdb:1ERI|rcsb pdb:1QC9|rcsb pdb:1QPS|rcsb pdb:1QRH|rcsb pdb:1QRI|rcsb pdb:2OXV|refseq:WP_001565219.1|dip:DIP-16997N go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0009036"(type II site-specific deoxyribonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|interpro:IPR004221(Restriction endonuclease, type II, EcoRI)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011336(Restriction endonuclease, type II, EcoRi/MunI, core)|interpro:IPR018131|rcsb pdb:1CKQ|rcsb pdb:1CL8|rcsb pdb:1ERI|rcsb pdb:1QC9|rcsb pdb:1QPS|rcsb pdb:1QRH|rcsb pdb:1QRI|rcsb pdb:2OXV|refseq:WP_001565219.1|dip:DIP-16997N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:7esYSfsiYA8ddAFM2dqufpDq2X4562 rogid:7esYSfsiYA8ddAFM2dqufpDq2X4562 rigid:FQZI6erp6ilh9iXlFlRj5epjvCg false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)