#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q91572 uniprotkb:P70032 intact:EBI-65730|uniprotkb:B7ZRW6|uniprotkb:B7ZRZ4 intact:EBI-3511304|uniprotkb:Q7ZWQ6 psi-mi:cpe1a_xenla(display_long)|uniprotkb:58 kDa CPE-binding protein(gene name synonym)|uniprotkb:cpeb1-a(gene name)|psi-mi:cpeb1-a(display_short)|uniprotkb:cpeb(gene name synonym) psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short) psi-mi:"MI:0096"(pull down) Setoyama et al. (2007) pubmed:17986610|doi:10.1073/pnas.0706952104|imex:IM-9438 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15669041|imex:IM-9438-1|dip:DIP-88031E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001084072.1|dip:DIP-30935N|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032292|interpro:IPR032296|interpro:IPR034819|interpro:IPR034977|interpro:IPR035979|interpro:IPR038446 mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947 psi-mi:"MI:0465"(dip) crc64:EF812949F5B4DE54 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/05 2017/08/10 rogid:dvE3Ql8r2wSvsH3lxzh41HkycFk8355 rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355 rigid:lu2ApmKVbTa8d+eMhNX0Y0sJ7XA false glutathione s tranferase tag:n-n|mutation decreasing interaction:125-125 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91854 uniprotkb:Q91572 intact:EBI-7161238|uniprotkb:P70038|intact:MINT-4052492|uniprotkb:P70037|uniprotkb:Q6AX69 intact:EBI-65730|uniprotkb:B7ZRW6|uniprotkb:B7ZRZ4 psi-mi:trcb_xenla(display_long)|uniprotkb:fbxw1(gene name)|psi-mi:fbxw1(display_short)|uniprotkb:btrcp(gene name synonym)|uniprotkb:Beta-transducin repeat-containing protein(gene name synonym) psi-mi:cpe1a_xenla(display_long)|uniprotkb:58 kDa CPE-binding protein(gene name synonym)|uniprotkb:cpeb1-a(gene name)|psi-mi:cpeb1-a(display_short)|uniprotkb:cpeb(gene name synonym) psi-mi:"MI:0096"(pull down) Setoyama et al. (2007) pubmed:17986610|doi:10.1073/pnas.0706952104|imex:IM-9438 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15669064|imex:IM-9438-2|dip:DIP-88030E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q91854|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001081064.1|dip:DIP-44075N refseq:NP_001084072.1|dip:DIP-30935N|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032292|interpro:IPR032296|interpro:IPR034819|interpro:IPR034977|interpro:IPR035979|interpro:IPR038446 psi-mi:"MI:0465"(dip) function:"Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. May participate in Wnt signaling"|comment:mint crc64:EF812949F5B4DE54 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/05 2017/08/10 rogid:eP5NUmwrCCQ1+6TctS7yelagu8I8355 rogid:dvE3Ql8r2wSvsH3lxzh41HkycFk8355 rigid:rAlFSBuBnm9J6uFQo6fujF74lx8 false myc tag:n-n glutathione s tranferase tag:n-n|mutation decreasing interaction:192-192 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91854 uniprotkb:Q91572 intact:EBI-7161238|uniprotkb:P70038|intact:MINT-4052492|uniprotkb:P70037|uniprotkb:Q6AX69 intact:EBI-65730|uniprotkb:B7ZRW6|uniprotkb:B7ZRZ4 psi-mi:trcb_xenla(display_long)|uniprotkb:fbxw1(gene name)|psi-mi:fbxw1(display_short)|uniprotkb:btrcp(gene name synonym)|uniprotkb:Beta-transducin repeat-containing protein(gene name synonym) psi-mi:cpe1a_xenla(display_long)|uniprotkb:58 kDa CPE-binding protein(gene name synonym)|uniprotkb:cpeb1-a(gene name)|psi-mi:cpeb1-a(display_short)|uniprotkb:cpeb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Setoyama et al. (2007) pubmed:17986610|doi:10.1073/pnas.0706952104|imex:IM-9438 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15669088|imex:IM-9438-3|dip:DIP-88030E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q91854|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001081064.1|dip:DIP-44075N refseq:NP_001084072.1|dip:DIP-30935N|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032292|interpro:IPR032296|interpro:IPR034819|interpro:IPR034977|interpro:IPR035979|interpro:IPR038446 psi-mi:"MI:0465"(dip) function:"Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. May participate in Wnt signaling"|comment:mint crc64:EF812949F5B4DE54 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/05 2017/08/10 rogid:eP5NUmwrCCQ1+6TctS7yelagu8I8355 rogid:dvE3Ql8r2wSvsH3lxzh41HkycFk8355 rigid:rAlFSBuBnm9J6uFQo6fujF74lx8 false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)