#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P36108	uniprotkb:P52917	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663400|imex:IM-21150-1|dip:DIP-191018E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	psi-mi:"MI:0465"(dip)	crc64:200D07DB4C45DCBC	crc64:E65BCDB19C9510DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rigid:6jD9AF4X120cp6bpiznxdq5Ih2Q	false	sufficient binding region:183-232	sufficient binding region:1-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q97ZJ7	uniprotkb:Q97ZJ6	intact:EBI-15663453|ensemblbacteria:AAK41191	intact:EBI-15663442|ensemblbacteria:AAK41192	psi-mi:q97zj7_sacs2(display_long)|uniprotkb:SSO0909(locus name)	psi-mi:q97zj6_sacs2(display_long)|uniprotkb:SSO0910(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)")	taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663469|imex:IM-21150-3|dip:DIP-191020E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAK41191(transcript)|ensemblbacteria:SSO0909(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|rcsb pdb:2V6Y|rcsb pdb:4LGM|refseq:WP_009992337.1|dip:DIP-60244N	ensemblbacteria:AAK41192(transcript)|ensemblbacteria:SSO0910(gene)|interpro:IPR036388|rcsb pdb:2XVC|refseq:WP_009992338.1|dip:DIP-60243N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:YzzmOUns7WuKj7VmKgk+zbK6oII273057	rogid:i4681/inuAYxsmHTyaI0zTstvmI273057	rigid:K7TaM/KWavYAPGq51mE+xi6IXiE	false	sufficient binding region:1-83|fiash label:n-n	sufficient binding region:164-207	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P69771	uniprotkb:P52917	intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663492|imex:IM-21150-4|dip:DIP-191019E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	psi-mi:"MI:0465"(dip)	crc64:70D1CF4588A8C6E6	crc64:E65BCDB19C9510DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rigid:6zcXhvtbKCKmCZ0FDaaJqnF45iw	false	sufficient binding region:171-204	sufficient binding region:1-82|fiash label:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36108	uniprotkb:P52917	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663515|imex:IM-21150-5|dip:DIP-191018E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	psi-mi:"MI:0465"(dip)	crc64:200D07DB4C45DCBC	crc64:E65BCDB19C9510DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rigid:6jD9AF4X120cp6bpiznxdq5Ih2Q	false	sufficient binding region:218-232|mutation disrupting interaction strength:221-221|mutation disrupting interaction strength:224-224|mutation disrupting interaction strength:225-225|mutation disrupting interaction strength:228-228|mutation disrupting interaction strength:229-229	sufficient binding region:1-82|fiash label:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36108	uniprotkb:P52917	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663421|imex:IM-21150-2|dip:DIP-191018E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	psi-mi:"MI:0465"(dip)	crc64:200D07DB4C45DCBC	crc64:E65BCDB19C9510DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rigid:6jD9AF4X120cp6bpiznxdq5Ih2Q	false	sufficient binding region:120-232	sufficient binding region:1-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36108	uniprotkb:P52917	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0096"(pull down)	Obita et al. (2007)	pubmed:17928861|doi:10.1038/nature06171|imex:IM-21150	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15663553|imex:IM-21150-6|dip:DIP-191018E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	psi-mi:"MI:0465"(dip)	crc64:200D07DB4C45DCBC	crc64:E65BCDB19C9510DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rigid:6jD9AF4X120cp6bpiznxdq5Ih2Q	false	his tag:n-n	sufficient binding region:1-82|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)