#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04275 uniprotkb:P04275 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:"MI:0807"(comigration in gel electrophoresis) Purvis et al. (2007) pubmed:17895385|doi:10.1073/pnas.0705175104|imex:IM-9546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15661828|imex:IM-9546-1|dip:DIP-59153E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/05 2017/08/10 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 rigid:nTk3aWOmQhcI2IdB/8eR9TSlrvE false binding-associated region:764-1241 binding-associated region:764-1241 - 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)