#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33202 uniprotkb:P54860 intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C intact:EBI-20003|uniprotkb:D6VRG3|ensemblfungi:YDL190C psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:ufd2_yeast(display_long)|uniprotkb:UFD2(gene name)|psi-mi:UFD2(display_short)|uniprotkb:YDL190C(locus name)|uniprotkb:D1255(orf name)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ubiquitin conjugation factor E4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UFD2(gene name synonym) psi-mi:"MI:0096"(pull down) Tu et al. (2007) pubmed:17890322|doi:10.1073/pnas.0701369104|imex:IM-9543 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659819|imex:IM-9543-1|dip:DIP-88243E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 refseq:NP_010091.2|sgd:S000002349|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR019474|rcsb pdb:2QIZ|rcsb pdb:2QJ0|rcsb pdb:3M62|rcsb pdb:3M63|reactome:R-SCE-983168|ensemblfungi:YDL190C(gene)|ensemblfungi:YDL190C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|dip:DIP-5925N|mint:P54860 psi-mi:"MI:0465"(dip) crc64:A9B8B9D812C6216F crc64:877ACB59AC29634A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 rogid:E8YkPPAM7RTsLwjUHSHNCjQWq9M559292 rigid:0U+B4SR7lRVBeT199xeVQXAkdu8 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P33202 uniprotkb:P54860 intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C intact:EBI-20003|uniprotkb:D6VRG3|ensemblfungi:YDL190C psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:ufd2_yeast(display_long)|uniprotkb:UFD2(gene name)|psi-mi:UFD2(display_short)|uniprotkb:YDL190C(locus name)|uniprotkb:D1255(orf name)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ubiquitin conjugation factor E4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UFD2(gene name synonym) psi-mi:"MI:0096"(pull down) Tu et al. (2007) pubmed:17890322|doi:10.1073/pnas.0701369104|imex:IM-9543 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659836|imex:IM-9543-2|dip:DIP-88243E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 refseq:NP_010091.2|sgd:S000002349|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR019474|rcsb pdb:2QIZ|rcsb pdb:2QJ0|rcsb pdb:3M62|rcsb pdb:3M63|reactome:R-SCE-983168|ensemblfungi:YDL190C(gene)|ensemblfungi:YDL190C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|dip:DIP-5925N|mint:P54860 psi-mi:"MI:0465"(dip) crc64:A9B8B9D812C6216F crc64:877ACB59AC29634A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 rogid:E8YkPPAM7RTsLwjUHSHNCjQWq9M559292 rigid:0U+B4SR7lRVBeT199xeVQXAkdu8 false t7 tag:n-n t7 tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)