#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q91YV0	uniprotkb:P48985	intact:EBI-15658970|ensembl:ENSMUSP00000110628	intact:EBI-15659000|ensembl:ENSMUSP00000098903	psi-mi:q91yv0_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)	psi-mi:atoh1_mouse(display_long)|uniprotkb:Atoh1(gene name)|psi-mi:Atoh1(display_short)|uniprotkb:Ath1(gene name synonym)|uniprotkb:Helix-loop-helix protein mATH-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Flora et al. (2007)	pubmed:17878293|doi:10.1073/pnas.0707456104|imex:IM-9679	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15659039|imex:IM-9679-2|dip:DIP-88472E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000114977(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_006525825.1|dip:DIP-46433N	ensembl:ENSMUSG00000073043(gene)|ensembl:ENSMUST00000101351(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042667"(auditory receptor cell fate specification)|go:"GO:0042668"(auditory receptor cell fate determination)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045609"(positive regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000982"(positive regulation of inner ear receptor cell differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032661|interpro:IPR036638|refseq:NP_031526.1|dip:DIP-46434N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:8QjLUDwKsgalCqBPTNrEXEgtMkg10090	rogid:XKphKMUuUsB080XF/5hgtjY097E10090	rigid:4pq5HJWLpdLUHI5fkC8QLxq05w0	false	v5 tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q91YV0	uniprotkb:P48987	intact:EBI-15658970|ensembl:ENSMUSP00000110628	intact:EBI-1639335|uniprotkb:A0AQ36|uniprotkb:A0AQ37|uniprotkb:A0AQ43|uniprotkb:Q9VHU0|ensemblmetazoa:FBpp0081318	psi-mi:q91yv0_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)	psi-mi:ato_drome(display_long)|uniprotkb:ato(gene name)|psi-mi:ato(display_short)|uniprotkb:CG7508(orf name)	psi-mi:"MI:0018"(two hybrid)	Flora et al. (2007)	pubmed:17878293|doi:10.1073/pnas.0707456104|imex:IM-9679	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15658983|imex:IM-9679-1|dip:DIP-88471E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000114977(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_006525825.1|dip:DIP-46433N	refseq:NP_731223.1|flybase:FBgn0010433|dip:DIP-151N|ensemblmetazoa:FBgn0010433(gene)|ensemblmetazoa:FBtr0081828(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007460"(R8 cell fate commitment)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008038"(neuron recognition)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048801"(antennal joint morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:8QjLUDwKsgalCqBPTNrEXEgtMkg10090	rogid:idcKcfXTlBLN/Xxf7X/15gfxGag7227	rigid:TRln7ISTgcf32a39vbmUW3wOflY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15806-2	uniprotkb:P48985	intact:EBI-413585|ensembl:ENSMUSP00000100982	intact:EBI-15659000|ensembl:ENSMUSP00000098903	psi-mi:p15806-2(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym)	psi-mi:atoh1_mouse(display_long)|uniprotkb:Atoh1(gene name)|psi-mi:Atoh1(display_short)|uniprotkb:Ath1(gene name synonym)|uniprotkb:Helix-loop-helix protein mATH-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Flora et al. (2007)	pubmed:17878293|doi:10.1073/pnas.0707456104|imex:IM-9679	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15659081|imex:IM-9679-4|dip:DIP-88473E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105345(transcript)|intact:EBI-81370(tfe2_mouse)	ensembl:ENSMUSG00000073043(gene)|ensembl:ENSMUST00000101351(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042667"(auditory receptor cell fate specification)|go:"GO:0042668"(auditory receptor cell fate determination)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045609"(positive regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000982"(positive regulation of inner ear receptor cell differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032661|interpro:IPR036638|refseq:NP_031526.1|dip:DIP-46434N	psi-mi:"MI:0465"(dip)	isoform-comment:Contains a phosphothreonine at position 528. Contains a phosphoserine at position 533.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:e4BH3vr/brPozXccOZby0yDXxYI10090	rogid:XKphKMUuUsB080XF/5hgtjY097E10090	rigid:a//OKaPMqOyzIY4edNckKp96qJ0	false	v5 tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q91YV0	uniprotkb:P48985	intact:EBI-15658970|ensembl:ENSMUSP00000110628	intact:EBI-15659000|ensembl:ENSMUSP00000098903	psi-mi:q91yv0_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)	psi-mi:atoh1_mouse(display_long)|uniprotkb:Atoh1(gene name)|psi-mi:Atoh1(display_short)|uniprotkb:Ath1(gene name synonym)|uniprotkb:Helix-loop-helix protein mATH-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Flora et al. (2007)	pubmed:17878293|doi:10.1073/pnas.0707456104|imex:IM-9679	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15659060|imex:IM-9679-3|dip:DIP-88472E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000114977(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_006525825.1|dip:DIP-46433N	ensembl:ENSMUSG00000073043(gene)|ensembl:ENSMUST00000101351(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042667"(auditory receptor cell fate specification)|go:"GO:0042668"(auditory receptor cell fate determination)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045609"(positive regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000982"(positive regulation of inner ear receptor cell differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032661|interpro:IPR036638|refseq:NP_031526.1|dip:DIP-46434N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:8QjLUDwKsgalCqBPTNrEXEgtMkg10090	rogid:XKphKMUuUsB080XF/5hgtjY097E10090	rigid:4pq5HJWLpdLUHI5fkC8QLxq05w0	false	v5 tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q91YV0	uniprotkb:P48987	intact:EBI-15658970|ensembl:ENSMUSP00000110628	intact:EBI-1639335|uniprotkb:A0AQ36|uniprotkb:A0AQ37|uniprotkb:A0AQ43|uniprotkb:Q9VHU0|ensemblmetazoa:FBpp0081318	psi-mi:q91yv0_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)	psi-mi:ato_drome(display_long)|uniprotkb:ato(gene name)|psi-mi:ato(display_short)|uniprotkb:CG7508(orf name)	psi-mi:"MI:0018"(two hybrid)	Flora et al. (2007)	pubmed:17878293|doi:10.1073/pnas.0707456104|imex:IM-9679	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15659104|imex:IM-9679-5|dip:DIP-88471E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000114977(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_006525825.1|dip:DIP-46433N	refseq:NP_731223.1|flybase:FBgn0010433|dip:DIP-151N|ensemblmetazoa:FBgn0010433(gene)|ensemblmetazoa:FBtr0081828(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007460"(R8 cell fate commitment)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008038"(neuron recognition)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048801"(antennal joint morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:8QjLUDwKsgalCqBPTNrEXEgtMkg10090	rogid:idcKcfXTlBLN/Xxf7X/15gfxGag7227	rigid:TRln7ISTgcf32a39vbmUW3wOflY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)