#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30622-1 uniprotkb:Q14203 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657003|imex:IM-21778-1|dip:DIP-74048E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:P1kUujquFjSCsdzbRS/dIj3t/bQ false sufficient binding region:1406-1427 sufficient binding region:16-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657082|imex:IM-21778-4|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:56-128 sufficient binding region:1364-1427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0096"(pull down) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657051|imex:IM-21778-3|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:56-128|mutation disrupting interaction strength:98-98|mutation disrupting interaction strength:120-120 sufficient binding region:1364-1427|glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657024|imex:IM-21778-2|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:56-128|mutation decreasing interaction strength:98-98|mutation decreasing interaction strength:120-120 sufficient binding region:1406-1427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657103|imex:IM-21778-5|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:210-282|mutation decreasing interaction strength:252-252|mutation decreasing interaction strength:276-276 sufficient binding region:1406-1427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657212|imex:IM-21778-9|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:210-282 sufficient binding region:1364-1427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657188|imex:IM-21778-8|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:210-282|mutation decreasing interaction strength:238-238 sufficient binding region:1364-1390 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:Q14203 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657164|imex:IM-21778-7|dip:DIP-74048E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:P1kUujquFjSCsdzbRS/dIj3t/bQ false sufficient binding region:1406-1427 sufficient binding region:16-107|mutation decreasing interaction strength:68-68 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0096"(pull down) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657130|imex:IM-21778-6|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:210-282|mutation disrupting interaction strength:252-252|mutation disrupting interaction strength:276-276|mutation disrupting interaction strength:238-238 sufficient binding region:1364-1427|glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P30622-1 uniprotkb:P30622-1 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 intact:EBI-9640673|ensembl:ENSP00000303585|ensembl:ENSP00000351665 psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:p30622-1(display_long)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hayashi et al. (2007) pubmed:17828275|doi:10.1038/nsmb1299|imex:IM-21778 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15657233|imex:IM-21778-10|dip:DIP-192182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) intact:EBI-2683569(isoform-parent)|ensembl:ENSG00000130779(gene)|ensembl:ENST00000302528(transcript)|ensembl:ENST00000358808(transcript)|uniprotkb:P30622-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rogid:DASxDbtqr9/w3iwSs0rnXPH6Pkk9606 rigid:/4mtBMGAIT/RTagtuWzjuP98u9g false sufficient binding region:56-128 sufficient binding region:1364-1390 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)