#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q08048 uniprotkb:P08581 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655738|imex:IM-9701-1|dip:DIP-88525E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rigid:aYZbuU2JIyBbiLbNYXa9vxKy6Bw false binding-associated region:31-210 binding-associated region:25-567 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08048 uniprotkb:P08581 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655738|imex:IM-9701-1|dip:DIP-88525E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rigid:aYZbuU2JIyBbiLbNYXa9vxKy6Bw false binding-associated region:31-210 binding-associated region:25-567 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08581 uniprotkb:P14210 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655762|imex:IM-9701-2|dip:DIP-65574E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rigid:f7quTxFXVAc7wOyeq32qeIc4m/I false binding-associated region:25-567 binding-associated region:28-209 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08048 uniprotkb:Q08048 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655784|imex:IM-9701-3|dip:DIP-88526E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rigid:ERT2BixFL3WLBPi5Jz39qOEUWyc false binding-associated region:31-210 binding-associated region:31-210 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08581 uniprotkb:Q08048 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655802|imex:IM-9701-4|dip:DIP-88525E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rigid:aYZbuU2JIyBbiLbNYXa9vxKy6Bw false binding-associated region:25-567 binding-associated region:31-210 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14210 uniprotkb:P08581 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655842|imex:IM-9701-6|dip:DIP-65574E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rigid:f7quTxFXVAc7wOyeq32qeIc4m/I false binding-associated region:28-209 binding-associated region:25-567 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14210 uniprotkb:P08581 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655842|imex:IM-9701-6|dip:DIP-65574E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rigid:f7quTxFXVAc7wOyeq32qeIc4m/I false binding-associated region:28-209 binding-associated region:25-567 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14210 uniprotkb:P14210 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655824|imex:IM-9701-5|dip:DIP-88527E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rigid:D4vyrlZVGHWbu6kXwUM59deMQTY false binding-associated region:28-209 binding-associated region:28-209 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08048 uniprotkb:P08581 intact:EBI-15655650|ensembl:ENSMUSP00000030683|ensembl:ENSMUSP00000143424|uniprotkb:O55027|uniprotkb:Q53WS5|uniprotkb:Q61662|uniprotkb:Q64007|uniprotkb:Q6LBE6 intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860 psi-mi:hgf_mouse(display_long)|uniprotkb:Hgf(gene name)|psi-mi:Hgf(display_short)|uniprotkb:Hepatopoietin-A(gene name synonym)|uniprotkb:Scatter factor(gene name synonym) psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0038"(dynamic light scattering) Tolbert et al. (2007) pubmed:17804794|doi:10.1073/pnas.0704290104|imex:IM-9701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15655866|imex:IM-9701-7|dip:DIP-88525E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028864(gene)|ensembl:ENSMUST00000030683(transcript)|ensembl:ENSMUST00000199581(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:2QJ4|rcsb pdb:3HMR|rcsb pdb:4IUA|reactome:R-MMU-114608|reactome:R-MMU-1257604|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|dip:DIP-46456N|refseq:NP_001276387.1|refseq:NP_001276388.1|refseq:NP_001276389.1|refseq:NP_001276390.1|refseq:NP_034557.3 refseq:NP_000236.2|refseq:NP_001120972.1|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3U6H|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000105976(gene)|ensembl:ENST00000397752(transcript)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0005524"(ATP binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR011009(Protein kinase-like)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031016"(pancreas development)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0031116"(positive regulation of microtubule polymerization)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:1UX3|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3U6I|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|rcsb pdb:7MO7|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|dip:DIP-6023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:l5wmwHsOoKDzEGwrQ7uoa6bsfY010090 rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606 rigid:aYZbuU2JIyBbiLbNYXa9vxKy6Bw false binding-associated region:31-210 binding-associated region:25-567 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)