#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-4399559 uniprotkb:P27448 dip:DIP-24261N intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Murphy et al. (2007) pubmed:17726107|doi:10.1073/pnas.0703012104|imex:IM-9709 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15654833|imex:IM-9709-1|dip:DIP-88548E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2018/04/06 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606 rigid:e/H0LZnAWNihzDxLb0A/beds6kw false tag:0-0 sufficient binding region:320-375 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4399559 uniprotkb:P27448 dip:DIP-24261N intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Murphy et al. (2007) pubmed:17726107|doi:10.1073/pnas.0703012104|imex:IM-9709 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15654854|imex:IM-9709-2|dip:DIP-88548E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2018/04/06 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606 rigid:e/H0LZnAWNihzDxLb0A/beds6kw false - sufficient binding region:320-375 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)