#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12830 uniprotkb:P0DJM0 intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8 intact:EBI-1035388|uniprotkb:Q45GD5|uniprotkb:Q45GD6|uniprotkb:Q48748|uniprotkb:Q48749|uniprotkb:Q48750|uniprotkb:Q48752|uniprotkb:Q9EXG2|uniprotkb:P25146|ensemblbacteria:CAC98512 psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym) psi-mi:inla_lismo(display_long)|uniprotkb:inlA(gene name)|psi-mi:inlA(display_short)|uniprotkb:lmo0433(locus name) psi-mi:"MI:0065"(isothermal titration calorimetry) Wollert et al. (2007) pubmed:17715295|doi:10.1073/pnas.0702199104|imex:IM-9717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15654156|imex:IM-9717-1|dip:DIP-64666E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N interpro:IPR042229|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR012569(Leucine-rich repeat, adjacent)|rcsb pdb:1O6S|rcsb pdb:1O6T|rcsb pdb:1O6V|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMW|rcsb pdb:2OMY|rcsb pdb:2OMZ|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|rcsb pdb:2OMT|rcsb pdb:2OMX|interpro:IPR032675|interpro:IPR025875|refseq:NP_463962.1|ensemblbacteria:CAC98512(gene)|ensemblbacteria:CAC98512(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|refseq:WP_010989462.1|reactome:R-HSA-8876493|interpro:IPR024634|interpro:IPR019931 psi-mi:"MI:0465"(dip) - crc64:4D1B03A5CF7CCDE3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606 rogid:4ViVCEMCXKCemi3X2NehkCOOljI169963 rigid:wGiIkJItsgC4mMeHOZK6EuLZh4k false binding-associated region:1-105 mutation increasing interaction strength:369-369|mutation increasing interaction strength:369-369|mutation increasing interaction:192-192|binding-associated region:36-496 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12830 uniprotkb:P0DJM0 intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8 intact:EBI-1035388|uniprotkb:Q45GD5|uniprotkb:Q45GD6|uniprotkb:Q48748|uniprotkb:Q48749|uniprotkb:Q48750|uniprotkb:Q48752|uniprotkb:Q9EXG2|uniprotkb:P25146|ensemblbacteria:CAC98512 psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym) psi-mi:inla_lismo(display_long)|uniprotkb:inlA(gene name)|psi-mi:inlA(display_short)|uniprotkb:lmo0433(locus name) psi-mi:"MI:0114"(x-ray crystallography) Wollert et al. (2007) pubmed:17715295|doi:10.1073/pnas.0702199104|imex:IM-9717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15654188|imex:IM-9717-2|dip:DIP-64666E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N interpro:IPR042229|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR012569(Leucine-rich repeat, adjacent)|rcsb pdb:1O6S|rcsb pdb:1O6T|rcsb pdb:1O6V|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMW|rcsb pdb:2OMY|rcsb pdb:2OMZ|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|rcsb pdb:2OMT|rcsb pdb:2OMX|interpro:IPR032675|interpro:IPR025875|refseq:NP_463962.1|ensemblbacteria:CAC98512(gene)|ensemblbacteria:CAC98512(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|refseq:WP_010989462.1|reactome:R-HSA-8876493|interpro:IPR024634|interpro:IPR019931 psi-mi:"MI:0465"(dip) - crc64:4D1B03A5CF7CCDE3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606 rogid:4ViVCEMCXKCemi3X2NehkCOOljI169963 rigid:wGiIkJItsgC4mMeHOZK6EuLZh4k false binding-associated region:1-105 mutation increasing interaction strength:369-369|mutation increasing interaction strength:369-369|mutation increasing interaction:192-192|binding-associated region:36-496 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)