#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61758 uniprotkb:P35963 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 intact:EBI-911612 psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:pol_hv1y2(display_long)|uniprotkb:Pr160Gag-Pol(gene name synonym)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short) psi-mi:"MI:0018"(two hybrid) Mousnier et al. (2007) pubmed:17698809|doi:10.1073/pnas.0705162104|imex:IM-9725 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15651980|imex:IM-9725-1|dip:DIP-88569E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 dip:DIP-45385N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|interpro:IPR034170|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1F6U|rcsb pdb:1K6C|rcsb pdb:1K6P|rcsb pdb:1K6T|rcsb pdb:1K6V|rcsb pdb:1MFS|rcsb pdb:1T7I|rcsb pdb:1T7J|rcsb pdb:1WJA|rcsb pdb:1WJC|rcsb pdb:2JO0|rcsb pdb:2L6E|rcsb pdb:3OQ7|rcsb pdb:3OQA|rcsb pdb:3OQD|rcsb pdb:3OTS|rcsb pdb:3OTY|rcsb pdb:3OU1|rcsb pdb:3OU3|rcsb pdb:3OU4|rcsb pdb:3OUA|rcsb pdb:3OUB|rcsb pdb:3OUC|rcsb pdb:3OUD|rcsb pdb:3PJ6|rcsb pdb:3U7S|rcsb pdb:4A6B|rcsb pdb:4A6C psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2019/04/15 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rogid:PtKizZqPUXKTQWSsItE+o2B8uS4362651 rigid:Hh81AG+6MewGBMnLHLA/LyGhvZo false - polyprotein fragment:1148-1435 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35963 uniprotkb:P40337 intact:EBI-911612 intact:EBI-301246|uniprotkb:Q13599|uniprotkb:B2RE45|uniprotkb:Q6PDA9|ensembl:ENSP00000256474 psi-mi:pol_hv1y2(display_long)|uniprotkb:Pr160Gag-Pol(gene name synonym)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short) psi-mi:vhl_human(display_long)|uniprotkb:VHL(gene name)|psi-mi:VHL(display_short)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Protein G7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mousnier et al. (2007) pubmed:17698809|doi:10.1073/pnas.0705162104|imex:IM-9725 taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15652018|imex:IM-9725-3|dip:DIP-88570E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45385N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|interpro:IPR034170|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1F6U|rcsb pdb:1K6C|rcsb pdb:1K6P|rcsb pdb:1K6T|rcsb pdb:1K6V|rcsb pdb:1MFS|rcsb pdb:1T7I|rcsb pdb:1T7J|rcsb pdb:1WJA|rcsb pdb:1WJC|rcsb pdb:2JO0|rcsb pdb:2L6E|rcsb pdb:3OQ7|rcsb pdb:3OQA|rcsb pdb:3OQD|rcsb pdb:3OTS|rcsb pdb:3OTY|rcsb pdb:3OU1|rcsb pdb:3OU3|rcsb pdb:3OU4|rcsb pdb:3OUA|rcsb pdb:3OUB|rcsb pdb:3OUC|rcsb pdb:3OUD|rcsb pdb:3PJ6|rcsb pdb:3U7S|rcsb pdb:4A6B|rcsb pdb:4A6C rcsb pdb:6BVB|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:4W9I|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:4W9J|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:4W9K|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6SIS|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-1234176|reactome:R-HSA-3232142|rcsb pdb:4W9L|reactome:R-HSA-8951664|rcsb pdb:4WQO|reactome:R-HSA-9682706|reactome:R-HSA-9694686|reactome:R-HSA-9706019|reactome:R-HSA-983168|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|ensembl:ENSG00000134086(gene)|ensembl:ENST00000256474(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050821"(protein stabilization)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|mint:P40337|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|refseq:NP_000542.1|refseq:NP_937799.1|dip:DIP-32585N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:PtKizZqPUXKTQWSsItE+o2B8uS4362651 rogid:KaCKDTSj0xPG9YmfFsXIbkRt3A89606 rigid:OI7bdVYQzSal3K3HC3vteWBe2ck false ha tag:n-n|polyprotein fragment:1148-1435 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61758 uniprotkb:P35963 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 intact:EBI-911612 psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:pol_hv1y2(display_long)|uniprotkb:Pr160Gag-Pol(gene name synonym)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short) psi-mi:"MI:0018"(two hybrid) Mousnier et al. (2007) pubmed:17698809|doi:10.1073/pnas.0705162104|imex:IM-9725 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15651999|imex:IM-9725-2|dip:DIP-88569E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 dip:DIP-45385N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|interpro:IPR034170|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1F6U|rcsb pdb:1K6C|rcsb pdb:1K6P|rcsb pdb:1K6T|rcsb pdb:1K6V|rcsb pdb:1MFS|rcsb pdb:1T7I|rcsb pdb:1T7J|rcsb pdb:1WJA|rcsb pdb:1WJC|rcsb pdb:2JO0|rcsb pdb:2L6E|rcsb pdb:3OQ7|rcsb pdb:3OQA|rcsb pdb:3OQD|rcsb pdb:3OTS|rcsb pdb:3OTY|rcsb pdb:3OU1|rcsb pdb:3OU3|rcsb pdb:3OU4|rcsb pdb:3OUA|rcsb pdb:3OUB|rcsb pdb:3OUC|rcsb pdb:3OUD|rcsb pdb:3PJ6|rcsb pdb:3U7S|rcsb pdb:4A6B|rcsb pdb:4A6C psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2019/04/15 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rogid:PtKizZqPUXKTQWSsItE+o2B8uS4362651 rigid:Hh81AG+6MewGBMnLHLA/LyGhvZo false - polyprotein fragment:1148-1435 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61758 uniprotkb:P35963 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 intact:EBI-911612 psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:pol_hv1y2(display_long)|uniprotkb:Pr160Gag-Pol(gene name synonym)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mousnier et al. (2007) pubmed:17698809|doi:10.1073/pnas.0705162104|imex:IM-9725 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15652041|imex:IM-9725-4|dip:DIP-88569E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 dip:DIP-45385N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|interpro:IPR034170|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1F6U|rcsb pdb:1K6C|rcsb pdb:1K6P|rcsb pdb:1K6T|rcsb pdb:1K6V|rcsb pdb:1MFS|rcsb pdb:1T7I|rcsb pdb:1T7J|rcsb pdb:1WJA|rcsb pdb:1WJC|rcsb pdb:2JO0|rcsb pdb:2L6E|rcsb pdb:3OQ7|rcsb pdb:3OQA|rcsb pdb:3OQD|rcsb pdb:3OTS|rcsb pdb:3OTY|rcsb pdb:3OU1|rcsb pdb:3OU3|rcsb pdb:3OU4|rcsb pdb:3OUA|rcsb pdb:3OUB|rcsb pdb:3OUC|rcsb pdb:3OUD|rcsb pdb:3PJ6|rcsb pdb:3U7S|rcsb pdb:4A6B|rcsb pdb:4A6C psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2019/04/15 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rogid:PtKizZqPUXKTQWSsItE+o2B8uS4362651 rigid:Hh81AG+6MewGBMnLHLA/LyGhvZo false myc tag:n-n ha tag:n-n|polyprotein fragment:1148-1435 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)