#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16310	uniprotkb:P52296	intact:EBI-7383787|uniprotkb:Q64236|intact:MINT-4588405|uniprotkb:Q80XW9|ensembl:ENSRNOP00000044119	intact:EBI-917731|intact:EBI-11702595	psi-mi:ghr_rat(display_long)|uniprotkb:Ghr(gene name)|psi-mi:Ghr(display_short)|uniprotkb:Somatotropin receptor(gene name synonym)	psi-mi:imb1_rat(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Conway-Campbell et al. (2007)	pubmed:17690250|doi:10.1073/pnas.0600181104|imex:IM-9734	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15651327|imex:IM-9734-1|dip:DIP-88588E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008758976.1|rgd:2687|refseq:NP_058790.1|ensembl:ENSRNOG00000015654(gene)|ensembl:ENSRNOT00000046951(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032094"(response to food)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0034097"(response to cytokine)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|reactome:R-RNO-1170546|reactome:R-RNO-982772|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|dip:DIP-63N	go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|reactome:R-RNO-140342|reactome:R-RNO-1655829|reactome:R-RNO-6798695|reactome:R-RNO-909733|rgd:2909|refseq:NP_058759.1|mint:P52296|dip:DIP-37024N	psi-mi:"MI:0465"(dip)	function:Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway|comment:mint|function:"The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:dazvxWCK8/PnACZxoC5RRUKmIIY10116	rogid:i8sGTTT4N+V1jz6fLjdodopKXfQ10116	rigid:nhtMEDs+vMAy/Vp9S+o3UOBFI2I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16310	uniprotkb:Q9Z0N9	intact:EBI-7383787|uniprotkb:Q64236|intact:MINT-4588405|uniprotkb:Q80XW9|ensembl:ENSRNOP00000044119	intact:EBI-15651307	psi-mi:ghr_rat(display_long)|uniprotkb:Ghr(gene name)|psi-mi:Ghr(display_short)|uniprotkb:Somatotropin receptor(gene name synonym)	psi-mi:q9z0n9_rat(display_long)|uniprotkb:importin alpha(gene name)|psi-mi:importin alpha(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Conway-Campbell et al. (2007)	pubmed:17690250|doi:10.1073/pnas.0600181104|imex:IM-9734	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15651327|imex:IM-9734-1|dip:DIP-88588E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008758976.1|rgd:2687|refseq:NP_058790.1|ensembl:ENSRNOG00000015654(gene)|ensembl:ENSRNOT00000046951(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032094"(response to food)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0034097"(response to cytokine)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|reactome:R-RNO-1170546|reactome:R-RNO-982772|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|dip:DIP-63N	go:"GO:0006606"(protein import into nucleus)|go:"GO:0045202"(synapse)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|go:"GO:0005737"(cytoplasm)|dip:DIP-46496N	psi-mi:"MI:0465"(dip)	function:Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway|comment:mint|function:"The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:dazvxWCK8/PnACZxoC5RRUKmIIY10116	rogid:6ute+Ib0t7GhI8i6sc+0c5RTq+010116	rigid:nhtMEDs+vMAy/Vp9S+o3UOBFI2I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)