#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60341-1 uniprotkb:Q96BD5 intact:EBI-15599570|ensembl:ENSP00000349049 intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824 psi-mi:o60341-1(display_long)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650664|imex:IM-21173-1|dip:DIP-191053E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710124(isoform-parent)|ensembl:ENSG00000004487(gene)|ensembl:ENST00000356634(transcript) refseq:NP_001095272.1|refseq:NP_057705.3|ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0046872"(metal ion binding)|go:"GO:1990391"(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|dip:DIP-60252N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rigid:hK3Kq2lEr6Zyg5kyhBLDYYe0RgY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60341-1 uniprotkb:Q9UKL0 intact:EBI-15599570|ensembl:ENSP00000349049 intact:EBI-926563|uniprotkb:Q15044|uniprotkb:Q6P2I9|uniprotkb:Q86VG5|intact:EBI-11087913|uniprotkb:J3KN32|ensembl:ENSP00000262241 psi-mi:o60341-1(display_long)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:rcor1_human(display_long)|uniprotkb:RCOR1(gene name)|psi-mi:RCOR1(display_short)|uniprotkb:KIAA0071(gene name synonym)|uniprotkb:RCOR(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650664|imex:IM-21173-1|dip:DIP-191053E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710124(isoform-parent)|ensembl:ENSG00000004487(gene)|ensembl:ENST00000356634(transcript) refseq:NP_055971.2|dip:DIP-35263N|ensembl:ENSG00000089902(gene)|ensembl:ENST00000262241(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9UKL0|rcsb pdb:2IW5|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|reactome:R-HSA-3214815|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-983231 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rogid:B1KfnjicGzKdWGnGGrZwjgpMQ309606 rigid:hK3Kq2lEr6Zyg5kyhBLDYYe0RgY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60341-1 uniprotkb:Q13547 intact:EBI-15599570|ensembl:ENSP00000349049 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:o60341-1(display_long)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650664|imex:IM-21173-1|dip:DIP-191053E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710124(isoform-parent)|ensembl:ENSG00000004487(gene)|ensembl:ENST00000356634(transcript) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rigid:hK3Kq2lEr6Zyg5kyhBLDYYe0RgY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BD5-1 intact:EBI-15634422 intact:EBI-15650685|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15650695|imex:IM-21173-2|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false sufficient binding region:486-543 N6,N6-dimethyl-L-lysine:4-4|N6-methyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BD5 intact:EBI-15634422 intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15650720|imex:IM-21173-3|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_001095272.1|refseq:NP_057705.3|ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0046872"(metal ion binding)|go:"GO:1990391"(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|dip:DIP-60252N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false - biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BD5-1 intact:EBI-15634422 intact:EBI-15650685|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0114"(x-ray crystallography) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15650743|imex:IM-21173-4|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false sufficient binding region:486-543 sufficient binding region:1-10 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BD5-1 intact:EBI-15634422 intact:EBI-15650685|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15650765|imex:IM-21173-5|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false glutathione s tranferase tag:?-?|sufficient binding region:486-543 biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4|N6-methyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-15634422 uniprotkb:Q96BD5 dip:DIP-29329N intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650799|imex:IM-21173-6|dip:DIP-191054E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_001095272.1|refseq:NP_057705.3|ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0046872"(metal ion binding)|go:"GO:1990391"(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|dip:DIP-60252N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rigid:8qRY8y2CnhHzD0wxGJlL7+PrV3Y false biotin tag:0-0 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15634422 uniprotkb:O60341-1 dip:DIP-29329N intact:EBI-15599570|ensembl:ENSP00000349049 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:o60341-1(display_long)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650799|imex:IM-21173-6|dip:DIP-191054E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - intact:EBI-710124(isoform-parent)|ensembl:ENSG00000004487(gene)|ensembl:ENST00000356634(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:8qRY8y2CnhHzD0wxGJlL7+PrV3Y false biotin tag:0-0 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15634422 uniprotkb:O60341-1 dip:DIP-29329N intact:EBI-15599570|ensembl:ENSP00000349049 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:o60341-1(display_long)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650819|imex:IM-21173-7|dip:DIP-191054E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - intact:EBI-710124(isoform-parent)|ensembl:ENSG00000004487(gene)|ensembl:ENST00000356634(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:8qRY8y2CnhHzD0wxGJlL7+PrV3Y false biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4 glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-15634422 uniprotkb:Q96BD5-1 dip:DIP-29329N intact:EBI-15650685|ensembl:ENSP00000398824 psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15650819|imex:IM-21173-7|dip:DIP-191054E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rigid:8qRY8y2CnhHzD0wxGJlL7+PrV3Y false biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4 glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96BD5-1 intact:EBI-15634422 intact:EBI-15650685|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15650848|imex:IM-21173-8|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false necessary binding region:486-532|glutathione s tranferase tag:?-?|sufficient binding region:486-543|mutation disrupting interaction strength:489-489|mutation disrupting interaction strength:502-502 biotin tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96BD5-1 intact:EBI-15634422 intact:EBI-15650685|ensembl:ENSP00000398824 dip:DIP-29329N psi-mi:q96bd5-1(display_long)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym) psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long) psi-mi:"MI:0096"(pull down) Lan et al. (2007) pubmed:17687328|doi:10.1038/nature06034|imex:IM-21173 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15650881|imex:IM-21173-9|dip:DIP-191055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000135365(gene)|ensembl:ENST00000418153(transcript)|intact:EBI-745085(isoform-parent) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2 rigid:GX0PKWztn7MWbX4vS0S1N9aQUS0 false sufficient binding region:486-543|his tag:?-? biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)