#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-15650351	uniprotkb:Q9UJW3-1	dip:DIP-48374N	intact:EBI-15650345|ensembl:ENSP00000486001	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:q9ujw3-1(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650354|imex:IM-21172-1|dip:DIP-191049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|intact:EBI-740967(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606	rigid:5xspMWFGQqt+5l83SODKxBuG2Ms	false	sufficient binding region:1-7	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15650351	uniprotkb:Q9UJW3-1	dip:DIP-48374N	intact:EBI-15650345|ensembl:ENSP00000486001	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:q9ujw3-1(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short)	psi-mi:"MI:0096"(pull down)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650376|imex:IM-21172-2|dip:DIP-191049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|intact:EBI-740967(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606	rigid:5xspMWFGQqt+5l83SODKxBuG2Ms	false	biotin tag:0-0|N6-methyl-L-lysine:4-4|N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15650351	uniprotkb:Q9UJW3-1	dip:DIP-48374N	intact:EBI-15650345|ensembl:ENSP00000486001	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:q9ujw3-1(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650404|imex:IM-21172-3|dip:DIP-191049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|intact:EBI-740967(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606	rigid:5xspMWFGQqt+5l83SODKxBuG2Ms	false	fluorescein label:0-0	mutation disrupting interaction strength:107-107|mutation disrupting interaction strength:90-90	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61964	intact:EBI-15650351	intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097	dip:DIP-48374N	psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym)	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:"MI:0096"(pull down)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650429|imex:IM-21172-4|dip:DIP-191051E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N	-	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rigid:w52IiadBDgvmYZHrvCLGx0d6nCE	false	-	biotin tag:0-0|N6-methyl-L-lysine:4-4|N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88508-1	uniprotkb:Q9CWR8	intact:EBI-15650457|ensembl:ENSMUSP00000020991|ensembl:ENSMUSP00000134009	intact:EBI-3043871|ensembl:ENSMUSP00000000746|ensembl:ENSMUSP00000116970|ensembl:ENSMUSP00000121562	psi-mi:o88508-1(display_long)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym)|uniprotkb:Dnmt3a(gene name)|psi-mi:Dnmt3a(display_short)|uniprotkb:DNA methyltransferase MmuIIIA(gene name synonym)	psi-mi:dnm3l_mouse(display_long)|uniprotkb:Dnmt3l(gene name)|psi-mi:Dnmt3l(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650466|imex:IM-21172-5|dip:DIP-191034E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020661(gene)|ensembl:ENSMUST00000174817(transcript)|ensembl:ENSMUST00000020991(transcript)|intact:EBI-995154(isoform-parent)	refseq:NP_001271126.1|ensembl:ENSMUSG00000000730(gene)|ensembl:ENSMUST00000000746(transcript)|ensembl:ENSMUST00000138785(transcript)|ensembl:ENSMUST00000151242(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019899"(enzyme binding)|go:"GO:0032259"(methylation)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0071514"(genomic imprinting)|go:"GO:0006306"(DNA methylation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|refseq:NP_001075164.1|refseq:NP_062321.1|dip:DIP-49029N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:ZLqyo0sbBdWAlvbJ25rm+p58o5810090	rogid:5eTaaJeCQTpKh5Wd2MZP25DSexM10090	rigid:N7HD971s9sdYm89ZKE/INjejdlo	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CWR8	uniprotkb:O88509	intact:EBI-3043871|ensembl:ENSMUSP00000000746|ensembl:ENSMUSP00000116970|ensembl:ENSMUSP00000121562	intact:EBI-7987547|intact:MINT-2523761|uniprotkb:O88510|uniprotkb:O88511|ensembl:ENSMUSP00000072761|ensembl:ENSMUSP00000105396	psi-mi:dnm3l_mouse(display_long)|uniprotkb:Dnmt3l(gene name)|psi-mi:Dnmt3l(display_short)	psi-mi:dnm3b_mouse(display_long)|uniprotkb:Dnmt3b(gene name)|psi-mi:Dnmt3b(display_short)|uniprotkb:DNA methyltransferase MmuIIIB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650485|imex:IM-21172-6|dip:DIP-191050E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271126.1|ensembl:ENSMUSG00000000730(gene)|ensembl:ENSMUST00000000746(transcript)|ensembl:ENSMUST00000138785(transcript)|ensembl:ENSMUST00000151242(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019899"(enzyme binding)|go:"GO:0032259"(methylation)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0071514"(genomic imprinting)|go:"GO:0006306"(DNA methylation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|refseq:NP_001075164.1|refseq:NP_062321.1|dip:DIP-49029N	refseq:NP_001258676.1|refseq:NP_001003961.2|refseq:NP_001258674.1|refseq:NP_001003960.2|refseq:NP_034198.3|refseq:NP_001258673.1|dip:DIP-43736N|ensembl:ENSMUSG00000027478(gene)|ensembl:ENSMUST00000072997(transcript)|ensembl:ENSMUST00000109774(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051718"("DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates")|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051719"("DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates")|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090116"(C-5 methylation of cytosine)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:O88509|rcsb pdb:1KHC|reactome:R-MMU-212300|reactome:R-MMU-4655427	psi-mi:"MI:0465"(dip)	-	comment:mint|function:Required for genome wide de novo methylation and is essential for development. DNA methylation is coordinated with methylation of histones	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:5eTaaJeCQTpKh5Wd2MZP25DSexM10090	rogid:kyLQKXAetZyuwqBYP3+08/cb5JU10090	rigid:OKkjbiJSuLlZ9TO9Jl5a4ZSykm8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9CWR8	uniprotkb:P62806	intact:EBI-3043871|ensembl:ENSMUSP00000000746|ensembl:ENSMUSP00000116970|ensembl:ENSMUSP00000121562	intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006	psi-mi:dnm3l_mouse(display_long)|uniprotkb:Dnmt3l(gene name)|psi-mi:Dnmt3l(display_short)	psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650485|imex:IM-21172-6|dip:DIP-191050E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271126.1|ensembl:ENSMUSG00000000730(gene)|ensembl:ENSMUST00000000746(transcript)|ensembl:ENSMUST00000138785(transcript)|ensembl:ENSMUST00000151242(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019899"(enzyme binding)|go:"GO:0032259"(methylation)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0071514"(genomic imprinting)|go:"GO:0006306"(DNA methylation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|refseq:NP_001075164.1|refseq:NP_062321.1|dip:DIP-49029N	ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:5eTaaJeCQTpKh5Wd2MZP25DSexM10090	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090	rigid:OKkjbiJSuLlZ9TO9Jl5a4ZSykm8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9CWR8	uniprotkb:O88508-1	intact:EBI-3043871|ensembl:ENSMUSP00000000746|ensembl:ENSMUSP00000116970|ensembl:ENSMUSP00000121562	intact:EBI-15650457|ensembl:ENSMUSP00000020991|ensembl:ENSMUSP00000134009	psi-mi:dnm3l_mouse(display_long)|uniprotkb:Dnmt3l(gene name)|psi-mi:Dnmt3l(display_short)	psi-mi:o88508-1(display_long)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym)|uniprotkb:Dnmt3a(gene name)|psi-mi:Dnmt3a(display_short)|uniprotkb:DNA methyltransferase MmuIIIA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650485|imex:IM-21172-6|dip:DIP-191050E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271126.1|ensembl:ENSMUSG00000000730(gene)|ensembl:ENSMUST00000000746(transcript)|ensembl:ENSMUST00000138785(transcript)|ensembl:ENSMUST00000151242(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019899"(enzyme binding)|go:"GO:0032259"(methylation)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0071514"(genomic imprinting)|go:"GO:0006306"(DNA methylation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|refseq:NP_001075164.1|refseq:NP_062321.1|dip:DIP-49029N	ensembl:ENSMUSG00000020661(gene)|ensembl:ENSMUST00000174817(transcript)|ensembl:ENSMUST00000020991(transcript)|intact:EBI-995154(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:5eTaaJeCQTpKh5Wd2MZP25DSexM10090	rogid:ZLqyo0sbBdWAlvbJ25rm+p58o5810090	rigid:OKkjbiJSuLlZ9TO9Jl5a4ZSykm8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
intact:EBI-15650351	uniprotkb:Q9UJW3-1	dip:DIP-48374N	intact:EBI-15650345|ensembl:ENSP00000486001	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:q9ujw3-1(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650506|imex:IM-21172-7|dip:DIP-191049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|intact:EBI-740967(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606	rigid:5xspMWFGQqt+5l83SODKxBuG2Ms	false	fluorescein label:0-0|N6-methyl-L-lysine:4-4|N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15650351	uniprotkb:Q9UJW3-1	dip:DIP-48374N	intact:EBI-15650345|ensembl:ENSP00000486001	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:q9ujw3-1(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short)	psi-mi:"MI:0096"(pull down)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650534|imex:IM-21172-8|dip:DIP-191049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|intact:EBI-740967(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606	rigid:5xspMWFGQqt+5l83SODKxBuG2Ms	false	biotin tag:0-0	mutation disrupting interaction strength:107-107|mutation disrupting interaction strength:90-90	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45973	intact:EBI-15650351	intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9	dip:DIP-48374N	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	psi-mi:h3tail(display_short)|psi-mi:EBI-15650351(display_long)	psi-mi:"MI:0096"(pull down)	Ooi et al. (2007)	pubmed:17687327|doi:10.1038/nature05987|imex:IM-21172	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15650559|imex:IM-21172-9|dip:DIP-191052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N	-	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	rogid:0VFN9RDwetpyCQswy/SJHgWy/EU-2	rigid:+zNBp2haxj9WUQwruuyF36Aa4/Q	false	-	biotin tag:0-0|N6-methyl-L-lysine:9-9|N6,N6-dimethyl-L-lysine:9-9|N6,N6,N6-trimethyl-L-lysine:9-9	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)