#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27782 uniprotkb:Q9QZR5 intact:EBI-984464|ensembl:ENSMUSP00000029611 intact:EBI-366905|uniprotkb:O88905|uniprotkb:Q99P45|uniprotkb:Q99P46|uniprotkb:Q9D2E6|uniprotkb:Q9D474|uniprotkb:Q9EQL2|uniprotkb:Q9QZR4|ensembl:ENSMUSP00000124133 psi-mi:lef1_mouse(display_long)|uniprotkb:Lef1(gene name)|psi-mi:Lef1(display_short)|uniprotkb:Lef-1(gene name synonym) psi-mi:hipk2_mouse(display_long)|uniprotkb:Hipk2(gene name)|psi-mi:Hipk2(display_short)|uniprotkb:Nbak1(gene name synonym)|uniprotkb:Stank(gene name synonym)|uniprotkb:Nuclear body-associated kinase 1(gene name synonym)|uniprotkb:Sialophorin tail-associated nuclear serine/threonine-protein kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wei et al. (2007) pubmed:17666529|doi:10.1073/pnas.0703213104|imex:IM-9736 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15649858|imex:IM-9736-1|dip:DIP-88593E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001944"(vasculature development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021861"(forebrain radial glial cell differentiation)|ensembl:ENSMUST00000029611(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0021873"(forebrain neuroblast division)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042100"(B cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048468"(cell development)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060033"(anatomical structure regression)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0061153"(trachea gland development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:0043586"(tongue development)|go:"GO:0043923"(positive regulation by host of viral transcription)|ensembl:ENSMUSG00000027985(gene)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028769|interpro:IPR036910|rcsb pdb:2LEF|rcsb pdb:3OUW|rcsb pdb:3OUX|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-4641265|reactome:R-MMU-8853884|reactome:R-MMU-8951430|refseq:NP_034833.2|dip:DIP-35132N refseq:NP_001129537.1|refseq:NP_034563.2|ensembl:ENSMUSG00000061436|ensembl:ENSMUSG00000061436(gene)|ensembl:ENSMUST00000161779(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9QZR5|reactome:R-MMU-3899300|reactome:R-MMU-6804756|reactome:R-MMU-8939243|reactome:R-MMU-9022692|refseq:NP_001281072.1|refseq:NP_001281073.1|dip:DIP-31712N psi-mi:"MI:0465"(dip) - crc64:5C863BE377F3AAEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:clPGB7wopoDgQGcfPmc78dgSfxs10090 rogid:QuwURfphVnnlJdiKOk6l4fDgtQM10090 rigid:czlcwQpn6Ea63llB1YJgQ93qTo0 false ha tag:n-n enhanced green fluorescent protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)