#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31007 uniprotkb:P08510 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:"MI:0096"(pull down) Magidovich et al. (2007) pubmed:17666528|doi:10.1073/pnas.0704059104|imex:IM-22891 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15649806|imex:IM-22891-1|dip:DIP-69781E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 rigid:ZtOdkSBeH8ufRJag7xNsv1AfpA0 false green fluorescent protein tag:c-c his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P31007 uniprotkb:P08510 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:"MI:0096"(pull down) Magidovich et al. (2007) pubmed:17666528|doi:10.1073/pnas.0704059104|imex:IM-22891 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15649827|imex:IM-22891-2|dip:DIP-69781E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 rigid:ZtOdkSBeH8ufRJag7xNsv1AfpA0 false sufficient binding region:216-421 his tag:n-n - - psi-mi:"MI:0815"(confirmation by molecular weight) psi-mi:"MI:0815"(confirmation by molecular weight)