#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P23381 uniprotkb:P23381 intact:EBI-721244|uniprotkb:P78535|uniprotkb:Q9UDL3|uniprotkb:A6NGN1|uniprotkb:A6NID3|uniprotkb:Q502Y0|uniprotkb:Q53XB6|uniprotkb:Q9UDI5|ensembl:ENSP00000347495|ensembl:ENSP00000376620|ensembl:ENSP00000451460 intact:EBI-721244|uniprotkb:P78535|uniprotkb:Q9UDL3|uniprotkb:A6NGN1|uniprotkb:A6NID3|uniprotkb:Q502Y0|uniprotkb:Q53XB6|uniprotkb:Q9UDI5|ensembl:ENSP00000347495|ensembl:ENSP00000376620|ensembl:ENSP00000451460 psi-mi:sywc_human(display_long)|uniprotkb:WARS1(gene name)|psi-mi:WARS1(display_short)|uniprotkb:IFI53(gene name synonym)|uniprotkb:Interferon-induced protein 53(gene name synonym)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:WARS(gene name synonym)|uniprotkb:WRS(gene name synonym) psi-mi:sywc_human(display_long)|uniprotkb:WARS1(gene name)|psi-mi:WARS1(display_short)|uniprotkb:IFI53(gene name synonym)|uniprotkb:Interferon-induced protein 53(gene name synonym)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:WARS(gene name synonym)|uniprotkb:WRS(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yang et al. (2007) pubmed:17637340|doi:10.1016/j.str.2007.05.009|imex:IM-8798 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15648043|imex:IM-8798-1|dip:DIP-58926E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004175.2|refseq:NP_776049.1|refseq:NP_998810.1|refseq:NP_998811.1|refseq:XP_011535435.1|refseq:XP_011535437.1|refseq:XP_011535438.1|refseq:XP_005268101.1|ensembl:ENSG00000140105(gene)|ensembl:ENST00000355338(transcript)|ensembl:ENST00000392882(transcript)|ensembl:ENST00000557135(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|refseq:XP_006720312.1|refseq:XP_016877116.1|refseq:XP_016877117.1|refseq:XP_016877118.1|dip:DIP-29493N|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:1O5T|rcsb pdb:1R6T|rcsb pdb:1R6U|rcsb pdb:1ULH|rcsb pdb:2AKE|rcsb pdb:2AZX|rcsb pdb:2DR2|rcsb pdb:2QUH|rcsb pdb:2QUI|rcsb pdb:2QUJ|rcsb pdb:2QUK|rcsb pdb:5UJI|rcsb pdb:5UJJ|reactome:R-HSA-379716 refseq:NP_004175.2|refseq:NP_776049.1|refseq:NP_998810.1|refseq:NP_998811.1|refseq:XP_011535435.1|refseq:XP_011535437.1|refseq:XP_011535438.1|refseq:XP_005268101.1|ensembl:ENSG00000140105(gene)|ensembl:ENST00000355338(transcript)|ensembl:ENST00000392882(transcript)|ensembl:ENST00000557135(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|refseq:XP_006720312.1|refseq:XP_016877116.1|refseq:XP_016877117.1|refseq:XP_016877118.1|dip:DIP-29493N|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:1O5T|rcsb pdb:1R6T|rcsb pdb:1R6U|rcsb pdb:1ULH|rcsb pdb:2AKE|rcsb pdb:2AZX|rcsb pdb:2DR2|rcsb pdb:2QUH|rcsb pdb:2QUI|rcsb pdb:2QUJ|rcsb pdb:2QUK|rcsb pdb:5UJI|rcsb pdb:5UJJ|reactome:R-HSA-379716 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:6suwKlk27+kV9FyX3trqGpVJ9xk9606 rogid:6suwKlk27+kV9FyX3trqGpVJ9xk9606 rigid:CnJjRzLiptUd6a4x/8zuxvzSgQk false sufficient binding region:48-471 sufficient binding region:48-471 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)