#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-4399559	uniprotkb:A0AVT1-1	dip:DIP-24261N	intact:EBI-15644956|ensembl:ENSP00000313454	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:a0avt1-1(display_long)|uniprotkb:UBA6(gene name)|psi-mi:UBA6(display_short)|uniprotkb:MOP4(gene name synonym)|uniprotkb:UBE1L2(gene name synonym)|uniprotkb:Monocyte protein 4(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15644966|imex:IM-21851-1|dip:DIP-192283E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	intact:EBI-5282516(isoform-parent)|ensembl:ENSG00000033178(gene)|ensembl:ENST00000322244(transcript)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:LIwlZDxN2wYLIdCXxm1UoGw8XYI9606	rigid:3+zSR4SoacuXdVxh384tDcoXSXQ	false	-	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:P22314	dip:DIP-24261N	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15644966|imex:IM-21851-1|dip:DIP-192283E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rigid:3+zSR4SoacuXdVxh384tDcoXSXQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:A0AVT1-1	dip:DIP-24261N	intact:EBI-15644956|ensembl:ENSP00000313454	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:a0avt1-1(display_long)|uniprotkb:UBA6(gene name)|psi-mi:UBA6(display_short)|uniprotkb:MOP4(gene name synonym)|uniprotkb:UBE1L2(gene name synonym)|uniprotkb:Monocyte protein 4(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein 2(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0195"(covalent binding)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645009|imex:IM-21851-3|dip:DIP-192284E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	intact:EBI-5282516(isoform-parent)|ensembl:ENSG00000033178(gene)|ensembl:ENST00000322244(transcript)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:LIwlZDxN2wYLIdCXxm1UoGw8XYI9606	rigid:pTvYDml+qi/xNf5CKoTqs4ZET90	false	-	flag tag:?-?|mutation disrupting interaction strength:625-625	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:A0AVT1-1	dip:DIP-24261N	intact:EBI-15644956|ensembl:ENSP00000313454	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:a0avt1-1(display_long)|uniprotkb:UBA6(gene name)|psi-mi:UBA6(display_short)|uniprotkb:MOP4(gene name synonym)|uniprotkb:UBE1L2(gene name synonym)|uniprotkb:Monocyte protein 4(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein 2(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15644988|imex:IM-21851-2|dip:DIP-192284E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	intact:EBI-5282516(isoform-parent)|ensembl:ENSG00000033178(gene)|ensembl:ENST00000322244(transcript)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:LIwlZDxN2wYLIdCXxm1UoGw8XYI9606	rigid:pTvYDml+qi/xNf5CKoTqs4ZET90	false	-	flag tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05161	uniprotkb:P41226	intact:EBI-746466|uniprotkb:Q7Z2G2|uniprotkb:Q96GF0|intact:EBI-1056284|uniprotkb:Q5SVA4|ensembl:ENSP00000496832	intact:EBI-751921|uniprotkb:Q9BRB2|ensembl:ENSP00000333266	psi-mi:isg15_human(display_long)|uniprotkb:ISG15(gene name)|psi-mi:ISG15(display_short)|uniprotkb:G1P2(gene name synonym)|uniprotkb:UCRP(gene name synonym)|uniprotkb:Interferon-induced 15 kDa protein(gene name synonym)|uniprotkb:Interferon-induced 17 kDa protein(gene name synonym)|uniprotkb:Ubiquitin cross-reactive protein(gene name synonym)	psi-mi:uba7_human(display_long)|uniprotkb:UBE1L(gene name synonym)|uniprotkb:UBE2(gene name synonym)|uniprotkb:UBA7(gene name)|psi-mi:UBA7(display_short)|uniprotkb:Ubiquitin-activating enzyme E1 homolog(gene name synonym)|uniprotkb:D8(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645033|imex:IM-21851-4|dip:DIP-192285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005092.1|ensembl:ENSG00000187608(gene)|ensembl:ENST00000649529(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009615"(response to virus)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031386"(protein tag)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0032461"(positive regulation of protein oligomerization)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0070585"(protein localization to mitochondrion)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|mint:P05161|rcsb pdb:1Z2M|rcsb pdb:2HJ8|rcsb pdb:3PHX|rcsb pdb:3PSE|rcsb pdb:3R66|rcsb pdb:3RT3|rcsb pdb:3SDL|rcsb pdb:5TL6|rcsb pdb:5W8T|rcsb pdb:5W8U|rcsb pdb:6BI8|rcsb pdb:6FFA|rcsb pdb:6XA9|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-909733|reactome:R-HSA-936440|dip:DIP-29814N	refseq:NP_003326.2|dip:DIP-60526N|ensembl:ENSG00000182179(gene)|ensembl:ENST00000333486(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019782"(ISG15 activating enzyme activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0032446"(protein modification by small protein conjugation)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-936440|reactome:R-HSA-983168|go:"GO:0005524"(ATP binding)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:k01VuKv72XNTX3hhlIT4Lr0Xl849606	rogid:SQ25p6ScP5T89S0GtIhukmWjQGQ9606	rigid:MDLTRKz3TTrHQiOCSy7cLf/BTPs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:A0AVT1-1	dip:DIP-24261N	intact:EBI-15644956|ensembl:ENSP00000313454	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:a0avt1-1(display_long)|uniprotkb:UBA6(gene name)|psi-mi:UBA6(display_short)|uniprotkb:MOP4(gene name synonym)|uniprotkb:UBE1L2(gene name synonym)|uniprotkb:Monocyte protein 4(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein 2(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645091|imex:IM-21851-7|dip:DIP-192284E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	intact:EBI-5282516(isoform-parent)|ensembl:ENSG00000033178(gene)|ensembl:ENST00000322244(transcript)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:LIwlZDxN2wYLIdCXxm1UoGw8XYI9606	rigid:pTvYDml+qi/xNf5CKoTqs4ZET90	false	-	flag tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-4399559	uniprotkb:A0AVT1-1	dip:DIP-24261N	intact:EBI-15644956|ensembl:ENSP00000313454	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:a0avt1-1(display_long)|uniprotkb:UBA6(gene name)|psi-mi:UBA6(display_short)|uniprotkb:MOP4(gene name synonym)|uniprotkb:UBE1L2(gene name synonym)|uniprotkb:Monocyte protein 4(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645067|imex:IM-21851-6|dip:DIP-192284E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	intact:EBI-5282516(isoform-parent)|ensembl:ENSG00000033178(gene)|ensembl:ENST00000322244(transcript)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:LIwlZDxN2wYLIdCXxm1UoGw8XYI9606	rigid:pTvYDml+qi/xNf5CKoTqs4ZET90	false	-	ha tag:?-?|mutation disrupting interaction strength:625-625	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P22314	intact:EBI-4399559	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	dip:DIP-24261N	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645050|imex:IM-21851-5|dip:DIP-191143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:8SxOU4MV/2jEAwcW1vcZ6hG9eAw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22314	intact:EBI-4399559	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	dip:DIP-24261N	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0808"(comigration in sds page)	Jin et al. (2007)	pubmed:17597759|doi:10.1038/nature05902|imex:IM-21851	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15645112|imex:IM-21851-8|dip:DIP-191143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:8SxOU4MV/2jEAwcW1vcZ6hG9eAw	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)