#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75533-1 uniprotkb:Q96I25 intact:EBI-15565798|ensembl:ENSP00000335321 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15643998|imex:IM-8707-3|dip:DIP-58782E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript) refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:Cx3HgmcK7ukK/oVkYQlZPIdCy/4 false sufficient binding region:330-341|glutathione s tranferase tag:n-n sufficient binding region:301-401|mutation disrupting interaction:319-319|mutation decreasing interaction:329-329|mutation disrupting interaction:375-375|mutation disrupting interaction:376-376|mutation disrupting interaction:377-377|mutation disrupting interaction strength:319-321 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q15637 uniprotkb:Q96I25 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644060|imex:IM-8707-7|dip:DIP-58781E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:7j9p+DyeufS7KUOF0MMQ60H1f6M false sufficient binding region:1-25|glutathione s tranferase tag:n-n sufficient binding region:301-401|mutation disrupting interaction:375-375|mutation disrupting interaction:319-319|mutation disrupting interaction:319-319|mutation decreasing interaction:375-375|mutation decreasing interaction:376-376|mutation decreasing interaction:377-377|mutation decreasing interaction:377-377 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P26368 uniprotkb:Q96I25 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644104|imex:IM-8707-6|dip:DIP-58780E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:WDmSNh53Q+YZNkdXAOC+r+0kxhg false sufficient binding region:85-112|glutathione s tranferase tag:n-n sufficient binding region:301-401|mutation disrupting interaction:375-375|mutation disrupting interaction:319-319|mutation disrupting interaction:329-329|mutation disrupting interaction:375-375|mutation decreasing interaction:377-377|mutation disrupting interaction strength:319-321 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q15637 uniprotkb:Q96I25 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644145|imex:IM-8707-2|dip:DIP-58781E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:7j9p+DyeufS7KUOF0MMQ60H1f6M false sufficient binding region:1-25 sufficient binding region:301-401 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75533-1 uniprotkb:Q96I25 intact:EBI-15565798|ensembl:ENSP00000335321 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644166|imex:IM-8707-5|dip:DIP-58782E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript) refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:Cx3HgmcK7ukK/oVkYQlZPIdCy/4 false sufficient binding region:317-357 sufficient binding region:301-401 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26368 uniprotkb:Q96I25 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644039|imex:IM-8707-1|dip:DIP-58780E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:WDmSNh53Q+YZNkdXAOC+r+0kxhg false sufficient binding region:85-112 sufficient binding region:301-401 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75533-1 uniprotkb:Q96I25 intact:EBI-15565798|ensembl:ENSP00000335321 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Corsini et al. (2007) pubmed:17589525|doi:10.1038/nsmb1260|imex:IM-8707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15644187|imex:IM-8707-4|dip:DIP-58782E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript) refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:Cx3HgmcK7ukK/oVkYQlZPIdCy/4 false sufficient binding region:333-342 sufficient binding region:301-401 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)