#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O76977	uniprotkb:O76977	intact:EBI-15641649|ensemblmetazoa:NP_999729	intact:EBI-15641649|ensemblmetazoa:NP_999729	psi-mi:o76977_strpu(display_long)	psi-mi:o76977_strpu(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Flynn et al. (2007)	pubmed:17562314|doi:10.1016/j.str.2007.04.008|imex:IM-8746	taxid:7668(strpu)|taxid:7668(Strongylocentrotus purpuratus)	taxid:7668(strpu)|taxid:7668(Strongylocentrotus purpuratus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15641666|imex:IM-8746-2|dip:DIP-57384E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:GeneID_373363(gene)|ensemblmetazoa:NM_214564(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR013621(Ion transport N-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:2PTM|refseq:NP_999729.1|dip:DIP-29325N	ensemblmetazoa:GeneID_373363(gene)|ensemblmetazoa:NM_214564(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR013621(Ion transport N-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:2PTM|refseq:NP_999729.1|dip:DIP-29325N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:zWI9BuXyVJ3UT1ti0f4nuRIUucI7668	rogid:zWI9BuXyVJ3UT1ti0f4nuRIUucI7668	rigid:H2LKPC2k9vc1a6cLqPe76PcfIwo	false	sufficient binding region:470-665	sufficient binding region:470-665	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88703	uniprotkb:O88703	intact:EBI-771231|uniprotkb:O70506|ensembl:ENSMUSP00000020581|ensembl:ENSMUSP00000097113	intact:EBI-771231|uniprotkb:O70506|ensembl:ENSMUSP00000020581|ensembl:ENSMUSP00000097113	psi-mi:hcn2_mouse(display_long)|uniprotkb:Brain cyclic nucleotide-gated channel 2(gene name synonym)|uniprotkb:Hyperpolarization-activated cation channel 1(gene name synonym)|uniprotkb:Bcng2(gene name synonym)|uniprotkb:Hac1(gene name synonym)|uniprotkb:Hcn2(gene name)|psi-mi:Hcn2(display_short)	psi-mi:hcn2_mouse(display_long)|uniprotkb:Brain cyclic nucleotide-gated channel 2(gene name synonym)|uniprotkb:Hyperpolarization-activated cation channel 1(gene name synonym)|uniprotkb:Bcng2(gene name synonym)|uniprotkb:Hac1(gene name synonym)|uniprotkb:Hcn2(gene name)|psi-mi:Hcn2(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Flynn et al. (2007)	pubmed:17562314|doi:10.1016/j.str.2007.04.008|imex:IM-8746	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15641685|imex:IM-8746-1|dip:DIP-57385E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032252.1|dip:DIP-29326N|ensembl:ENSMUSG00000020331(gene)|ensembl:ENSMUST00000020581(transcript)|ensembl:ENSMUST00000099513(transcript)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030552"(cAMP binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098855"(HCN channel complex)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR005821(Ion transport)|interpro:IPR013621(Ion transport N-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:O88703|rcsb pdb:1Q3E|rcsb pdb:1Q43|rcsb pdb:1Q5O|rcsb pdb:2Q0A|rcsb pdb:3BPZ|rcsb pdb:3ETQ|rcsb pdb:3FFQ|rcsb pdb:4EQF|rcsb pdb:5JON|rcsb pdb:5KHG|rcsb pdb:5KHH|rcsb pdb:5KHI|rcsb pdb:5KHJ|rcsb pdb:5KHK|reactome:R-MMU-1296061	refseq:NP_032252.1|dip:DIP-29326N|ensembl:ENSMUSG00000020331(gene)|ensembl:ENSMUST00000020581(transcript)|ensembl:ENSMUST00000099513(transcript)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030552"(cAMP binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098855"(HCN channel complex)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR005821(Ion transport)|interpro:IPR013621(Ion transport N-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:O88703|rcsb pdb:1Q3E|rcsb pdb:1Q43|rcsb pdb:1Q5O|rcsb pdb:2Q0A|rcsb pdb:3BPZ|rcsb pdb:3ETQ|rcsb pdb:3FFQ|rcsb pdb:4EQF|rcsb pdb:5JON|rcsb pdb:5KHG|rcsb pdb:5KHH|rcsb pdb:5KHI|rcsb pdb:5KHJ|rcsb pdb:5KHK|reactome:R-MMU-1296061	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:+2OZtagUBYgKm6J6eqLZzEkUkvg10090	rogid:+2OZtagUBYgKm6J6eqLZzEkUkvg10090	rigid:rkQb+5cbIgZf5TMAVUpkxYAc6jk	false	sufficient binding region:443-640	sufficient binding region:443-640	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)