#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32841 uniprotkb:P29467 intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714612|imex:IM-26322-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 - - - figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rigid:RT73VRxm81OWfXqTuP++oaHYEp4 false - necessary binding region:1-165|sufficient binding region:1-246 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32841 uniprotkb:P29467 intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714621|imex:IM-26322-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 - - - figure legend:Figure 4C|comment:Both the N-terminal and C-terminal regions of Rec114 are sufficient by themselves to support interaction with Mei4.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rigid:RT73VRxm81OWfXqTuP++oaHYEp4 false sufficient binding region:153-428|sufficient binding region:1-227 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32841 uniprotkb:Q02721 intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714637|imex:IM-26322-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 5F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:F48AcI6av0i6hrqimD1y4XWmEjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33323 uniprotkb:Q02721 intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714653|imex:IM-26322-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:EIMHvmxY+HDMmz/hfBXxVfvN6RA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33323 uniprotkb:Q02721 intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714657|imex:IM-26322-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 5Ei|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:EIMHvmxY+HDMmz/hfBXxVfvN6RA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23179 uniprotkb:Q02721 intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714662|imex:IM-26322-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23179 uniprotkb:P33323 intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714662|imex:IM-26322-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23179 uniprotkb:P33323 intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714889|imex:IM-26322-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23179 uniprotkb:Q02721 intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714889|imex:IM-26322-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:P33323 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714894|imex:IM-26322-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - crc64:C5E7B9D2268F9727 - figure legend:Figure 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:iRN9KJqJsOWVYMzktTrKdt1NX6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:Q02721 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714894|imex:IM-26322-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - crc64:C5E7B9D2268F9727 - figure legend:Figure 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:iRN9KJqJsOWVYMzktTrKdt1NX6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:P33323 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714899|imex:IM-26322-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - crc64:C5E7B9D2268F9727 - figure legend:Figure 6C-2|comment:The signal was reduced ∼2.5-fold in the Delta_rec114 strain.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:o1Y/mH4Tj235NDpnPPf51wAQovE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:P23179 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714899|imex:IM-26322-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N - crc64:C5E7B9D2268F9727 - figure legend:Figure 6C-2|comment:The signal was reduced ∼2.5-fold in the Delta_rec114 strain.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rigid:o1Y/mH4Tj235NDpnPPf51wAQovE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:Q02721 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714948|imex:IM-26322-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:skjPCAZk54qCCmO0ln/gH7lD+d4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P32841 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16714948|imex:IM-26322-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N - - - figure legend:Figure 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rigid:skjPCAZk54qCCmO0ln/gH7lD+d4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:Q02721 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715018|imex:IM-26322-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 6D-2|comment:Deletion of spo11 and rec104 reduced this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:ARQnXtDaBNTBalRGGSSVtQPSqUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P21651 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715018|imex:IM-26322-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N - - crc64:46F426AC0DFDFAD0 figure legend:Figure 6D-2|comment:Deletion of spo11 and rec104 reduced this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292 rigid:ARQnXtDaBNTBalRGGSSVtQPSqUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P33323 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715067|imex:IM-26322-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6E-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:VrgNbvlTPTaAng2LOh/E6hUQ9h8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P21651 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715067|imex:IM-26322-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N - - crc64:46F426AC0DFDFAD0 figure legend:Figure 6E-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292 rigid:VrgNbvlTPTaAng2LOh/E6hUQ9h8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P33323 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715073|imex:IM-26322-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6E-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:Z3PuXnLha7UbOcOkclwj1NB9g7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P32841 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715073|imex:IM-26322-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N - - - figure legend:Figure 6E-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rigid:Z3PuXnLha7UbOcOkclwj1NB9g7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P33323 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715105|imex:IM-26322-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6E-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:iO9Is+Cc4csEgrq86btw5SBhKOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:Q02721 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715105|imex:IM-26322-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N - - - figure legend:Figure 6E-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292 rigid:iO9Is+Cc4csEgrq86btw5SBhKOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P33323 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6 psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715110|imex:IM-26322-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200 - - - figure legend:Figure 6E-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:izd4XKs93wK7fXBQxDnwyI172/w559292 rigid:+OtL3oBM0zQe1HP0Z66WcXQ+kAw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29467 uniprotkb:P23179 intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name) psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715110|imex:IM-26322-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888 refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N - - - figure legend:Figure 6E-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292 rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292 rigid:+OtL3oBM0zQe1HP0Z66WcXQ+kAw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32841 uniprotkb:P21651 intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5 psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short) psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Maleki et al. (2007) imex:IM-26322|pubmed:17558514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16715116|imex:IM-26322-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N - - crc64:46F426AC0DFDFAD0 figure legend:Figure 6F|comment:"Mer2 still interacted with Rec114 in a mei4-delta strain, although with a LacZ signal reduced ∼ 2-fold. Similar two-hybrid signals were obtained in each of the other mutants tested, notably deletions of :- rec102, spo11 and rec104."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/11/17 2017/12/20 rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292 rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292 rigid:Cui17e+My6MeQtHvT7DhE6M2/6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)