#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14114	uniprotkb:Q60841	intact:EBI-2681187|uniprotkb:Q9BR78|uniprotkb:Q86V27|uniprotkb:Q99876|uniprotkb:O14968|uniprotkb:B1AMT6|uniprotkb:B1AMT7|uniprotkb:B1AMT8|ensembl:ENSP00000303634	intact:EBI-9248666|uniprotkb:E9PZ78|uniprotkb:Q9CUA6|ensembl:ENSMUSP00000124052	psi-mi:lrp8_human(display_long)|uniprotkb:APOER2(gene name synonym)|uniprotkb:Apolipoprotein E receptor 2(gene name synonym)|uniprotkb:LRP8(gene name)|psi-mi:LRP8(display_short)	psi-mi:reln_mouse(display_long)|uniprotkb:Reln(gene name)|psi-mi:Reln(display_short)|uniprotkb:Rl(gene name synonym)|uniprotkb:Reeler protein(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Yasui et al. (2007)	pubmed:17548821|doi:10.1073/pnas.0700438104|imex:IM-22854	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15640749|imex:IM-22854-1|dip:DIP-186293E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018064.1|refseq:NP_004622.2|refseq:NP_059992.3|refseq:NP_150643.2|ensembl:ENST00000306052(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008035"(high-density lipoprotein particle binding)|ensembl:ENSG00000157193(gene)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019894"(kinesin binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021541"(ammon gyrus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030229"(very-low-density lipoprotein particle receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038025"(reelin receptor activity)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|go:"GO:0009986"(cell surface)|interpro:IPR036055|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:5B4Y|reactome:R-HSA-432142|reactome:R-HSA-975634|dip:DIP-48670N	refseq:NP_035391.2|refseq:NP_001297393.1|dip:DIP-40924N|ensembl:ENSMUSG00000042453(gene)|ensembl:ENSMUST00000161356(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008306"(associative learning)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021511"(spinal cord patterning)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902078"(positive regulation of lateral motor column neuron migration)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002861(Reeler region)|interpro:IPR034968|interpro:IPR036278|interpro:IPR041161|interpro:IPR042307|rcsb pdb:2DDU|rcsb pdb:2E26|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:6A48|reactome:R-MMU-8866376	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:oyR4o/rVbVJRLCCUp1eChkHXiho9606	rogid:oh9CRa5hVZ2xTcmgcDNSLYX8etU10090	rigid:MGcSHf3VWiqHbvDmcuVXayphz5M	false	-	sufficient binding region:1948-2661	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14114	uniprotkb:Q60841	intact:EBI-2681187|uniprotkb:Q9BR78|uniprotkb:Q86V27|uniprotkb:Q99876|uniprotkb:O14968|uniprotkb:B1AMT6|uniprotkb:B1AMT7|uniprotkb:B1AMT8|ensembl:ENSP00000303634	intact:EBI-9248666|uniprotkb:E9PZ78|uniprotkb:Q9CUA6|ensembl:ENSMUSP00000124052	psi-mi:lrp8_human(display_long)|uniprotkb:APOER2(gene name synonym)|uniprotkb:Apolipoprotein E receptor 2(gene name synonym)|uniprotkb:LRP8(gene name)|psi-mi:LRP8(display_short)	psi-mi:reln_mouse(display_long)|uniprotkb:Reln(gene name)|psi-mi:Reln(display_short)|uniprotkb:Rl(gene name synonym)|uniprotkb:Reeler protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yasui et al. (2007)	pubmed:17548821|doi:10.1073/pnas.0700438104|imex:IM-22854	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15640768|imex:IM-22854-2|dip:DIP-186293E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018064.1|refseq:NP_004622.2|refseq:NP_059992.3|refseq:NP_150643.2|ensembl:ENST00000306052(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008035"(high-density lipoprotein particle binding)|ensembl:ENSG00000157193(gene)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019894"(kinesin binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021541"(ammon gyrus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030229"(very-low-density lipoprotein particle receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038025"(reelin receptor activity)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|go:"GO:0009986"(cell surface)|interpro:IPR036055|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:5B4Y|reactome:R-HSA-432142|reactome:R-HSA-975634|dip:DIP-48670N	refseq:NP_035391.2|refseq:NP_001297393.1|dip:DIP-40924N|ensembl:ENSMUSG00000042453(gene)|ensembl:ENSMUST00000161356(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008306"(associative learning)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021511"(spinal cord patterning)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902078"(positive regulation of lateral motor column neuron migration)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002861(Reeler region)|interpro:IPR034968|interpro:IPR036278|interpro:IPR041161|interpro:IPR042307|rcsb pdb:2DDU|rcsb pdb:2E26|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:6A48|reactome:R-MMU-8866376	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:oyR4o/rVbVJRLCCUp1eChkHXiho9606	rogid:oh9CRa5hVZ2xTcmgcDNSLYX8etU10090	rigid:MGcSHf3VWiqHbvDmcuVXayphz5M	false	fusion protein:n-n	sufficient binding region:1948-2661|myc tag:c-c|mutation disrupting interaction strength:2467-2467,2360-2360|mutation disrupting interaction strength:2467-2467|mutation disrupting interaction strength:2360-2360	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98155	uniprotkb:Q60841	intact:EBI-9004309|uniprotkb:B2RMZ7|uniprotkb:D3DRH6|uniprotkb:Q5VVF6|ensembl:ENSP00000371532	intact:EBI-9248666|uniprotkb:E9PZ78|uniprotkb:Q9CUA6|ensembl:ENSMUSP00000124052	psi-mi:vldlr_human(display_long)|uniprotkb:VLDLR(gene name)|psi-mi:VLDLR(display_short)	psi-mi:reln_mouse(display_long)|uniprotkb:Reln(gene name)|psi-mi:Reln(display_short)|uniprotkb:Rl(gene name synonym)|uniprotkb:Reeler protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yasui et al. (2007)	pubmed:17548821|doi:10.1073/pnas.0700438104|imex:IM-22854	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15640801|imex:IM-22854-3|dip:DIP-69355E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018066.1|refseq:NP_003374.3|dip:DIP-40925N|ensembl:ENST00000382100(transcript)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006869"(lipid transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007613"(memory)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030229"(very-low-density lipoprotein particle receptor activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034189"(very-low-density lipoprotein particle binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034436"(glycoprotein transport)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038025"(reelin receptor activity)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR032931|interpro:IPR036055|rcsb pdb:1V9U|rcsb pdb:3DPR|rcsb pdb:6BYV|reactome:R-HSA-8866376|reactome:R-HSA-8866427|reactome:R-HSA-8964046|ensembl:ENSG00000147852(gene)	refseq:NP_035391.2|refseq:NP_001297393.1|dip:DIP-40924N|ensembl:ENSMUSG00000042453(gene)|ensembl:ENSMUST00000161356(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008306"(associative learning)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021511"(spinal cord patterning)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902078"(positive regulation of lateral motor column neuron migration)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002861(Reeler region)|interpro:IPR034968|interpro:IPR036278|interpro:IPR041161|interpro:IPR042307|rcsb pdb:2DDU|rcsb pdb:2E26|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:6A48|reactome:R-MMU-8866376	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:4OC31+mjsJMCq1cZU3uHFIZu+Y09606	rogid:oh9CRa5hVZ2xTcmgcDNSLYX8etU10090	rigid:0Ka/UCXABUaV/bX4q+J1gr+8oN8	false	sufficient binding region:31-355|fusion protein:n-n	myc tag:c-c|sufficient binding region:1948-2661|mutation disrupting interaction strength:2467-2467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14114	uniprotkb:Q60841	intact:EBI-2681187|uniprotkb:Q9BR78|uniprotkb:Q86V27|uniprotkb:Q99876|uniprotkb:O14968|uniprotkb:B1AMT6|uniprotkb:B1AMT7|uniprotkb:B1AMT8|ensembl:ENSP00000303634	intact:EBI-9248666|uniprotkb:E9PZ78|uniprotkb:Q9CUA6|ensembl:ENSMUSP00000124052	psi-mi:lrp8_human(display_long)|uniprotkb:APOER2(gene name synonym)|uniprotkb:Apolipoprotein E receptor 2(gene name synonym)|uniprotkb:LRP8(gene name)|psi-mi:LRP8(display_short)	psi-mi:reln_mouse(display_long)|uniprotkb:Reln(gene name)|psi-mi:Reln(display_short)|uniprotkb:Rl(gene name synonym)|uniprotkb:Reeler protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yasui et al. (2007)	pubmed:17548821|doi:10.1073/pnas.0700438104|imex:IM-22854	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15640829|imex:IM-22854-4|dip:DIP-186293E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018064.1|refseq:NP_004622.2|refseq:NP_059992.3|refseq:NP_150643.2|ensembl:ENST00000306052(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008035"(high-density lipoprotein particle binding)|ensembl:ENSG00000157193(gene)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019894"(kinesin binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021541"(ammon gyrus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030229"(very-low-density lipoprotein particle receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038025"(reelin receptor activity)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|go:"GO:0009986"(cell surface)|interpro:IPR036055|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:5B4Y|reactome:R-HSA-432142|reactome:R-HSA-975634|dip:DIP-48670N	refseq:NP_035391.2|refseq:NP_001297393.1|dip:DIP-40924N|ensembl:ENSMUSG00000042453(gene)|ensembl:ENSMUST00000161356(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008306"(associative learning)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021511"(spinal cord patterning)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050795"(regulation of behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902078"(positive regulation of lateral motor column neuron migration)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002861(Reeler region)|interpro:IPR034968|interpro:IPR036278|interpro:IPR041161|interpro:IPR042307|rcsb pdb:2DDU|rcsb pdb:2E26|rcsb pdb:3A7Q|rcsb pdb:5B4X|rcsb pdb:6A48|reactome:R-MMU-8866376	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:oyR4o/rVbVJRLCCUp1eChkHXiho9606	rogid:oh9CRa5hVZ2xTcmgcDNSLYX8etU10090	rigid:MGcSHf3VWiqHbvDmcuVXayphz5M	false	sufficient binding region:42-83|fusion protein:n-n	myc tag:c-c|sufficient binding region:1948-2661	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)