#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01959 uniprotkb:O15354 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-15639515|ensembl:ENSP00000306449|uniprotkb:A4D0Y6|uniprotkb:O00348|uniprotkb:O14768|uniprotkb:Q8TD39 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:gpr37_human(display_long)|uniprotkb:GPR37(gene name)|psi-mi:GPR37(display_short)|uniprotkb:Endothelin B receptor-like protein 1(gene name synonym)|uniprotkb:G-protein coupled receptor 37(gene name synonym)|uniprotkb:Parkin-associated endothelin receptor-like receptor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marazziti et al. (2007) pubmed:17519329|doi:10.1073/pnas.0703368104|imex:IM-22843 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15639556|imex:IM-22843-1|dip:DIP-196893E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N ensembl:ENSG00000170775(gene)|ensembl:ENST00000303921(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009986"(cell surface)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0036505"(prosaposin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003909(GPR37 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:O15354|reactome:R-HSA-375276|reactome:R-HSA-418594|refseq:NP_005293.1|dip:DIP-60954N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:FDOvgBAlM9jMbNOCSOv0Fi+5HwA9606 rigid:xVTF8kfU4eYBbzjNoxvr9kx/lxU false - ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01959 uniprotkb:O15354 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-15639515|ensembl:ENSP00000306449|uniprotkb:A4D0Y6|uniprotkb:O00348|uniprotkb:O14768|uniprotkb:Q8TD39 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:gpr37_human(display_long)|uniprotkb:GPR37(gene name)|psi-mi:GPR37(display_short)|uniprotkb:Endothelin B receptor-like protein 1(gene name synonym)|uniprotkb:G-protein coupled receptor 37(gene name synonym)|uniprotkb:Parkin-associated endothelin receptor-like receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Marazziti et al. (2007) pubmed:17519329|doi:10.1073/pnas.0703368104|imex:IM-22843 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15639575|imex:IM-22843-2|dip:DIP-196893E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N ensembl:ENSG00000170775(gene)|ensembl:ENST00000303921(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009986"(cell surface)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0036505"(prosaposin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003909(GPR37 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:O15354|reactome:R-HSA-375276|reactome:R-HSA-418594|refseq:NP_005293.1|dip:DIP-60954N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:FDOvgBAlM9jMbNOCSOv0Fi+5HwA9606 rigid:xVTF8kfU4eYBbzjNoxvr9kx/lxU false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)