#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AFX9	uniprotkb:P0AFX7	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	intact:EBI-1117560|uniprotkb:P38106|uniprotkb:Q2MAF8|ensemblbacteria:AAC75625|ensemblbacteria:BAE76748	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:rsea_ecoli(display_long)|uniprotkb:yfiJ(gene name synonym)|uniprotkb:rseA(gene name)|psi-mi:rseA(display_short)|uniprotkb:mclA(gene name synonym)|uniprotkb:b2572(locus name)|uniprotkb:JW2556(locus name)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2007)	pubmed:17496148|doi:10.1073/pnas.0703117104|imex:IM-22828	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15636563|imex:IM-22828-2|dip:DIP-196860E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	refseq:NP_417067.1|ensemblbacteria:AAC75625(transcript)|ensemblbacteria:b2572(gene)|ensemblbacteria:BAE76748(gene)|ensemblbacteria:BAE76748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR026279|interpro:IPR036147|rcsb pdb:1OR7|rcsb pdb:1YFN|rcsb pdb:3M4W|refseq:WP_001168459.1|dip:DIP-39581N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rogid:tpuDQBjnIhDZEQzGSs4rw3+LLcg83333	rigid:ETr3AKrQJLykQXN0gE0x/o6UfZA	false	sufficient binding region:24-318	sufficient binding region:169-186|mutation disrupting interaction strength:172-172,171-171|mutation disrupting interaction strength:185-185,184-184|mutation disrupting interaction strength:172-172,171-171|mutation disrupting interaction strength:185-185,184-184|his tag:n-n	-	-	psi-mi:"MI:0815"(confirmation by molecular weight)	psi-mi:"MI:0815"(confirmation by molecular weight)
uniprotkb:P0AFX9	uniprotkb:P0AFX9	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Kim et al. (2007)	pubmed:17496148|doi:10.1073/pnas.0703117104|imex:IM-22828	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15636545|imex:IM-22828-1|dip:DIP-196859E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rigid:soxBpiK8zYTBTS07JL+u1Bdcq94	false	sufficient binding region:24-318	sufficient binding region:24-318	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFX7	uniprotkb:P0AFX9	intact:EBI-1117560|uniprotkb:P38106|uniprotkb:Q2MAF8|ensemblbacteria:AAC75625|ensemblbacteria:BAE76748	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	psi-mi:rsea_ecoli(display_long)|uniprotkb:yfiJ(gene name synonym)|uniprotkb:rseA(gene name)|psi-mi:rseA(display_short)|uniprotkb:mclA(gene name synonym)|uniprotkb:b2572(locus name)|uniprotkb:JW2556(locus name)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:"MI:0826"(x ray scattering)	Kim et al. (2007)	pubmed:17496148|doi:10.1073/pnas.0703117104|imex:IM-22828	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15636620|imex:IM-22828-4|dip:DIP-196860E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417067.1|ensemblbacteria:AAC75625(transcript)|ensemblbacteria:b2572(gene)|ensemblbacteria:BAE76748(gene)|ensemblbacteria:BAE76748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR026279|interpro:IPR036147|rcsb pdb:1OR7|rcsb pdb:1YFN|rcsb pdb:3M4W|refseq:WP_001168459.1|dip:DIP-39581N	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:tpuDQBjnIhDZEQzGSs4rw3+LLcg83333	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rigid:ETr3AKrQJLykQXN0gE0x/o6UfZA	false	-	sufficient binding region:24-318	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFX9	uniprotkb:P0AFX9	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:"MI:0826"(x ray scattering)	Kim et al. (2007)	pubmed:17496148|doi:10.1073/pnas.0703117104|imex:IM-22828	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15636602|imex:IM-22828-3|dip:DIP-196859E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rigid:soxBpiK8zYTBTS07JL+u1Bdcq94	false	sufficient binding region:24-318	sufficient binding region:24-318	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFX9	uniprotkb:P0AFX9	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	intact:EBI-1135231|uniprotkb:P46186|uniprotkb:Q2MAF9|ensemblbacteria:AAC75624|ensemblbacteria:BAE76747	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:rseb_ecoli(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:b2571(locus name)|uniprotkb:JW2555(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kim et al. (2007)	pubmed:17496148|doi:10.1073/pnas.0703117104|imex:IM-22828	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15636639|imex:IM-22828-5|dip:DIP-196859E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	refseq:NP_417066.1|refseq:WP_000812053.1|ensemblbacteria:AAC75624(transcript)|ensemblbacteria:b2571(gene)|ensemblbacteria:BAE76747(gene)|ensemblbacteria:BAE76747(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032885"(regulation of polysaccharide biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045152"(antisigma factor binding)|interpro:IPR005588(MucB/RseB)|interpro:IPR033434|interpro:IPR033436|interpro:IPR038484|rcsb pdb:2P4B|rcsb pdb:2V42|rcsb pdb:2V43|rcsb pdb:3M4W|dip:DIP-10802N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rogid:7NY/RGIsvGbRYeILn2jrnxpDzJA83333	rigid:soxBpiK8zYTBTS07JL+u1Bdcq94	false	sufficient binding region:24-318	sufficient binding region:24-318	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)