#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96LR5	uniprotkb:Q96EQ8	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633852|imex:IM-22809-2|dip:DIP-134464E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:gqXQ8qh4pbqCRDtbFUQajaJGEJo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EQ8	uniprotkb:O95786-1	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633829|imex:IM-22809-1|dip:DIP-196816E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:NJ+qPwM/a/Af/4QJE6PAXsw5WYc	false	ha tag:n-n	flag tag:n-n|sufficient binding region:1-238	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96EQ8	uniprotkb:O95786-1	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633907|imex:IM-22809-5|dip:DIP-196816E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:NJ+qPwM/a/Af/4QJE6PAXsw5WYc	false	ha tag:n-n	sufficient binding region:1-238|flag tag:n-n|sufficient binding region:239-734	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96EQ8	uniprotkb:Q96LR5	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633932|imex:IM-22809-6|dip:DIP-196818E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rigid:/XaHFyeKrnaHKw+2oGa5xu+x31E	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96EQ8	uniprotkb:O95786-1	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633932|imex:IM-22809-6|dip:DIP-196818E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:/XaHFyeKrnaHKw+2oGa5xu+x31E	false	ha tag:n-n	flag tag:n-n|sufficient binding region:1-238	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95786-1	uniprotkb:Q96EQ8	intact:EBI-15577823|ensembl:ENSP00000369213	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633890|imex:IM-22809-4|dip:DIP-196816E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:NJ+qPwM/a/Af/4QJE6PAXsw5WYc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z434-1	uniprotkb:Q96EQ8	intact:EBI-15577799|ensembl:ENSP00000401980	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633869|imex:IM-22809-3|dip:DIP-196817E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:MYbcCJErLm1p4QCYxIgd5/ibvuc	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BYX4	uniprotkb:Q96EQ8	intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633958|imex:IM-22809-7|dip:DIP-196819E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:JoUdRKAcB9z8AzWo317RauHZ+Tk	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:Q9BYX4	dip:DIP-24261N	intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633979|imex:IM-22809-8|dip:DIP-196820E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606	rigid:qx2snq7r0xEmE0GSpxUXR+WjyLM	false	myc tag:0-0	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:O95786-1	dip:DIP-24261N	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634000|imex:IM-22809-9|dip:DIP-196546E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:q6rDTp7AD+Et6LohbhAFWNmk1zQ	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z434-1	uniprotkb:Q96EQ8	intact:EBI-15577799|ensembl:ENSP00000401980	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634019|imex:IM-22809-10|dip:DIP-196817E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:MYbcCJErLm1p4QCYxIgd5/ibvuc	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BYX4	uniprotkb:Q96EQ8	intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634040|imex:IM-22809-11|dip:DIP-196819E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:JoUdRKAcB9z8AzWo317RauHZ+Tk	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96LR5	uniprotkb:Q96EQ8	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634061|imex:IM-22809-12|dip:DIP-134464E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:gqXQ8qh4pbqCRDtbFUQajaJGEJo	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:Q7Z434-1	dip:DIP-24261N	intact:EBI-15577799|ensembl:ENSP00000401980	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634082|imex:IM-22809-13|dip:DIP-196821E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rigid:xxYcF7ri6joGLTcLOnY7zB3tfos	false	myc tag:0-0	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:O95786-1	dip:DIP-24261N	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634103|imex:IM-22809-14|dip:DIP-196546E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:q6rDTp7AD+Et6LohbhAFWNmk1zQ	false	myc tag:0-0	sufficient binding region:1-238|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96LR5	uniprotkb:Q96EQ8	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634168|imex:IM-22809-17|dip:DIP-134464E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rigid:gqXQ8qh4pbqCRDtbFUQajaJGEJo	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96EQ8	uniprotkb:O95786-1	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-15577823|ensembl:ENSP00000369213	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634145|imex:IM-22809-16|dip:DIP-196816E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rigid:NJ+qPwM/a/Af/4QJE6PAXsw5WYc	false	ha tag:n-n|sufficient binding region:1-76	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:Q7Z434-1	dip:DIP-24261N	intact:EBI-15577799|ensembl:ENSP00000401980	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:"MI:0096"(pull down)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634126|imex:IM-22809-15|dip:DIP-196821E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rigid:xxYcF7ri6joGLTcLOnY7zB3tfos	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-4399559	uniprotkb:Q9BYX4	dip:DIP-24261N	intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Arimoto et al. (2007)	pubmed:17460044|doi:10.1073/pnas.0611551104|imex:IM-22809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15634189|imex:IM-22809-18|dip:DIP-196820E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606	rigid:qx2snq7r0xEmE0GSpxUXR+WjyLM	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)