#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q60857	uniprotkb:Q8CGF4	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-8311692|intact:MINT-1865707	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:q8cgf4_mouse(display_long)|uniprotkb:Sec24c(gene name)|psi-mi:Sec24c(display_short)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633398|imex:IM-22815-1|dip:DIP-196828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|dip:DIP-60924N|mint:Q8CGF4	psi-mi:"MI:0465"(dip)	-	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:iD5njV5p9MmxzAQbeQUuUFmnfFY10090	rigid:H+TpXrKyr1oUpI75+bSY3RGEnJs	false	sufficient binding region:616-630	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q60857	uniprotkb:Q63ZW7	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633398|imex:IM-22815-1|dip:DIP-196828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N	psi-mi:"MI:0465"(dip)	-	comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090	rigid:H+TpXrKyr1oUpI75+bSY3RGEnJs	false	sufficient binding region:616-630	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q60857	uniprotkb:Q01405	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-775901|ensembl:ENSMUSP00000021375|uniprotkb:Q8JZL4	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:sc23a_mouse(display_long)|uniprotkb:SEC23-related protein A(gene name synonym)|uniprotkb:Sec23a(gene name)|psi-mi:Sec23a(display_short)|uniprotkb:Sec23(gene name synonym)|uniprotkb:Sec23r(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633398|imex:IM-22815-1|dip:DIP-196828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	ensembl:ENSMUSG00000020986(gene)|ensembl:ENSMUST00000021375(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|refseq:NP_033173.2|refseq:XP_006515691.1|dip:DIP-32032N|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q01405|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-5694530|reactome:R-MMU-983170	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:0aSRfr1sJuL/w805EjjbO4tw/Hg10090	rigid:H+TpXrKyr1oUpI75+bSY3RGEnJs	false	sufficient binding region:616-630	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q60857	uniprotkb:Q9Z0J4	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633398|imex:IM-22815-1|dip:DIP-196828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rigid:H+TpXrKyr1oUpI75+bSY3RGEnJs	false	sufficient binding region:616-630	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9Z0J4	uniprotkb:Q60857	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633441|imex:IM-22815-3|dip:DIP-196830E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rigid:pawA+qjq/wfYiifmt75kPZhC+iQ	false	-	yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Z0J4	uniprotkb:Q60857	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633460|imex:IM-22815-4|dip:DIP-196830E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rigid:pawA+qjq/wfYiifmt75kPZhC+iQ	false	-	sufficient binding region:616-630	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61327	uniprotkb:Q63ZW7	intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974	intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3	psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym)	psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633420|imex:IM-22815-2|dip:DIP-196831E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N	ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N	psi-mi:"MI:0465"(dip)	function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint	comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090	rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090	rigid:EoTMrCsmF2Oap5NX2/ICUrWy4GQ	false	sufficient binding region:605-619	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61327	uniprotkb:Q62083	intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974	intact:EBI-77550|uniprotkb:E9PY04	psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym)	psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633420|imex:IM-22815-2|dip:DIP-196831E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N	go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993	psi-mi:"MI:0465"(dip)	function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090	rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090	rigid:EoTMrCsmF2Oap5NX2/ICUrWy4GQ	false	sufficient binding region:605-619	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61327	uniprotkb:Q9Z0J4	intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym)	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633420|imex:IM-22815-2|dip:DIP-196831E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	psi-mi:"MI:0465"(dip)	function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rigid:EoTMrCsmF2Oap5NX2/ICUrWy4GQ	false	sufficient binding region:605-619	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60857	uniprotkb:Q63ZW7	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633479|imex:IM-22815-5|dip:DIP-196829E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N	psi-mi:"MI:0465"(dip)	-	comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090	rigid:DeSJ/ilkmWEi4fy2UCLMDDQp01o	false	sufficient binding region:616-630|mutation disrupting interaction strength:630-630	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q60857	uniprotkb:Q62083	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-77550|uniprotkb:E9PY04	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633479|imex:IM-22815-5|dip:DIP-196829E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090	rigid:DeSJ/ilkmWEi4fy2UCLMDDQp01o	false	sufficient binding region:616-630|mutation disrupting interaction strength:630-630	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q60857	uniprotkb:Q01405	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-775901|ensembl:ENSMUSP00000021375|uniprotkb:Q8JZL4	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:sc23a_mouse(display_long)|uniprotkb:SEC23-related protein A(gene name synonym)|uniprotkb:Sec23a(gene name)|psi-mi:Sec23a(display_short)|uniprotkb:Sec23(gene name synonym)|uniprotkb:Sec23r(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633479|imex:IM-22815-5|dip:DIP-196829E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	ensembl:ENSMUSG00000020986(gene)|ensembl:ENSMUST00000021375(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|refseq:NP_033173.2|refseq:XP_006515691.1|dip:DIP-32032N|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q01405|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-5694530|reactome:R-MMU-983170	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:0aSRfr1sJuL/w805EjjbO4tw/Hg10090	rigid:DeSJ/ilkmWEi4fy2UCLMDDQp01o	false	sufficient binding region:616-630|mutation disrupting interaction strength:630-630	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q60857	uniprotkb:Q9Z0J4	intact:EBI-15633326|ensembl:ENSMUSP00000021195|ensembl:ENSMUSP00000104039|uniprotkb:O35241|uniprotkb:Q5NCR6	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	psi-mi:sc6a4_mouse(display_long)|uniprotkb:Slc6a4(gene name)|psi-mi:Slc6a4(display_short)|uniprotkb:Htt(gene name synonym)|uniprotkb:Sert(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym)	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chanrion et al. (2007)	pubmed:17452640|doi:10.1073/pnas.0610964104|imex:IM-22815	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15633479|imex:IM-22815-5|dip:DIP-196829E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020838(gene)|ensembl:ENSMUST00000021195(transcript)|ensembl:ENSMUST00000108402(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0006837"(serotonin transport)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|reactome:R-MMU-380615|refseq:NP_034614.2|refseq:XP_006532362.1|refseq:XP_006532363.1|refseq:XP_006532364.1|dip:DIP-60923N	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:kaRyGU08/1qRoJlOfBLwoHMTVAU10090	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rigid:DeSJ/ilkmWEi4fy2UCLMDDQp01o	false	sufficient binding region:616-630|mutation disrupting interaction strength:630-630	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)