#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8AXF4 uniprotkb:Q9PTN1 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-15630603 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q9ptn1_xenla(display_long)|uniprotkb:RSK2(gene name synonym)|uniprotkb:rps6ka3(gene name synonym)|uniprotkb:XELAEV_18011847mg(orf name)|uniprotkb:rps6ka3.L(gene name)|psi-mi:rps6ka3.L(display_short) psi-mi:"MI:0424"(protein kinase assay) Inoue et al. (2007) pubmed:17410130|doi:10.1038/nature05688|imex:IM-21836 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15630626|imex:IM-21836-1|dip:DIP-192257E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|refseq:NP_001084222.1|dip:DIP-60523N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:3lmdkD5JSkV43leYiTn1cdX1ubo8355 rigid:PxxSeW1KATWoN2OdQjNB+4/6TLs false O-phospho-L-serine:335-335|O-phospho-L-threonine:336-336|mutation disrupting interaction rate:336-336,335-335 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8AXF4 uniprotkb:Q9PTN1 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-15630603 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q9ptn1_xenla(display_long)|uniprotkb:RSK2(gene name synonym)|uniprotkb:rps6ka3(gene name synonym)|uniprotkb:XELAEV_18011847mg(orf name)|uniprotkb:rps6ka3.L(gene name)|psi-mi:rps6ka3.L(display_short) psi-mi:"MI:0424"(protein kinase assay) Inoue et al. (2007) pubmed:17410130|doi:10.1038/nature05688|imex:IM-21836 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15630651|imex:IM-21836-2|dip:DIP-192257E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|refseq:NP_001084222.1|dip:DIP-60523N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:3lmdkD5JSkV43leYiTn1cdX1ubo8355 rigid:PxxSeW1KATWoN2OdQjNB+4/6TLs false sufficient binding region:200-400|mutation decreasing interaction rate:336-336,335-335|mutation decreasing interaction rate:335-336,315-316,342-342 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8AXF4 uniprotkb:Q9PTN1 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-15630603 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q9ptn1_xenla(display_long)|uniprotkb:RSK2(gene name synonym)|uniprotkb:rps6ka3(gene name synonym)|uniprotkb:XELAEV_18011847mg(orf name)|uniprotkb:rps6ka3.L(gene name)|psi-mi:rps6ka3.L(display_short) psi-mi:"MI:0424"(protein kinase assay) Inoue et al. (2007) pubmed:17410130|doi:10.1038/nature05688|imex:IM-21836 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15630678|imex:IM-21836-3|dip:DIP-192257E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|refseq:NP_001084222.1|dip:DIP-60523N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:3lmdkD5JSkV43leYiTn1cdX1ubo8355 rigid:PxxSeW1KATWoN2OdQjNB+4/6TLs false sufficient binding region:200-400|mutation disrupting interaction rate:336-336,335-335|O-phospho-L-serine:335-335|O-phospho-L-threonine:336-336 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)