#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P97287	uniprotkb:Q9JM54	intact:EBI-707292|uniprotkb:D2K6L9|uniprotkb:Q3TUS0|uniprotkb:Q792P0|uniprotkb:Q9CRI4|ensembl:ENSMUSP00000044048	intact:EBI-709183|ensembl:ENSMUSP00000025399	psi-mi:mcl1_mouse(display_long)|uniprotkb:Bcl-2-related protein EAT/mcl1(gene name synonym)|uniprotkb:Mcl1(gene name)|psi-mi:Mcl1(display_short)	psi-mi:apr_mouse(display_long)|uniprotkb:Pmaip1(gene name)|psi-mi:Pmaip1(display_short)|uniprotkb:Noxa(gene name synonym)|uniprotkb:Protein Noxa(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Czabotar et al. (2007)	pubmed:17389404|doi:10.1073/pnas.0701297104|imex:IM-22788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15629439|imex:IM-22788-1|dip:DIP-78764E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032588.1|dip:DIP-33343N|ensembl:ENSMUSG00000038612(gene)|ensembl:ENSMUST00000037947(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034097"(response to cytokine)|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2ROC|rcsb pdb:2ROD|rcsb pdb:3D7V|rcsb pdb:3IO9|rcsb pdb:4BPI|rcsb pdb:4BPJ|rcsb pdb:4G35|rcsb pdb:5KU9|rcsb pdb:5MES|rcsb pdb:5MEV|rcsb pdb:5VX2|rcsb pdb:6DM8|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051400"(BH domain binding)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR013281(Apoptosis regulator, Mcl-1)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1WSX|rcsb pdb:2JM6|rcsb pdb:2NL9|rcsb pdb:2NLA	refseq:NP_067426.1|dip:DIP-45232N|ensembl:ENSMUSG00000024521(gene)|ensembl:ENSMUST00000025399(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR024140|rcsb pdb:2JM6|rcsb pdb:2NLA|rcsb pdb:2ROD|reactome:R-MMU-111448|reactome:R-MMU-111453	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:mzEFIihn4nh/O1UVSXggXEpJOKg10090	rogid:iK8kxdz7tYzg5/owvOIE79ObMB410090	rigid:YxEj8WrnqzThe36fZWMCUDxBKds	false	sufficient binding region:152-308	sufficient binding region:68-93	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JM54	uniprotkb:P97287	intact:EBI-709183|ensembl:ENSMUSP00000025399	intact:EBI-707292|uniprotkb:D2K6L9|uniprotkb:Q3TUS0|uniprotkb:Q792P0|uniprotkb:Q9CRI4|ensembl:ENSMUSP00000044048	psi-mi:apr_mouse(display_long)|uniprotkb:Pmaip1(gene name)|psi-mi:Pmaip1(display_short)|uniprotkb:Noxa(gene name synonym)|uniprotkb:Protein Noxa(gene name synonym)	psi-mi:mcl1_mouse(display_long)|uniprotkb:Bcl-2-related protein EAT/mcl1(gene name synonym)|uniprotkb:Mcl1(gene name)|psi-mi:Mcl1(display_short)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Czabotar et al. (2007)	pubmed:17389404|doi:10.1073/pnas.0701297104|imex:IM-22788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15629461|imex:IM-22788-2|dip:DIP-78764E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067426.1|dip:DIP-45232N|ensembl:ENSMUSG00000024521(gene)|ensembl:ENSMUST00000025399(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR024140|rcsb pdb:2JM6|rcsb pdb:2NLA|rcsb pdb:2ROD|reactome:R-MMU-111448|reactome:R-MMU-111453	refseq:NP_032588.1|dip:DIP-33343N|ensembl:ENSMUSG00000038612(gene)|ensembl:ENSMUST00000037947(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034097"(response to cytokine)|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2ROC|rcsb pdb:2ROD|rcsb pdb:3D7V|rcsb pdb:3IO9|rcsb pdb:4BPI|rcsb pdb:4BPJ|rcsb pdb:4G35|rcsb pdb:5KU9|rcsb pdb:5MES|rcsb pdb:5MEV|rcsb pdb:5VX2|rcsb pdb:6DM8|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051400"(BH domain binding)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR013281(Apoptosis regulator, Mcl-1)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1WSX|rcsb pdb:2JM6|rcsb pdb:2NL9|rcsb pdb:2NLA	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:iK8kxdz7tYzg5/owvOIE79ObMB410090	rogid:mzEFIihn4nh/O1UVSXggXEpJOKg10090	rigid:YxEj8WrnqzThe36fZWMCUDxBKds	false	sufficient binding region:68-93	sufficient binding region:152-308	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)