#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q79V60 uniprotkb:Q79V60 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0410"(3D electron microscopy) Mori et al. (2007) pubmed:17388688|doi:10.1371/journal.pbio.0050093|imex:IM-8674 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628386|imex:IM-8674-3|dip:DIP-57412E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 psi-mi:"MI:0465"(dip) crc64:34E4CDF9DE9C1824 crc64:34E4CDF9DE9C1824 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rigid:J34Cs6aVH71mufKg+r4ucWerICo false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V62 uniprotkb:Q79V60 intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0410"(3D electron microscopy) Mori et al. (2007) pubmed:17388688|doi:10.1371/journal.pbio.0050093|imex:IM-8674 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628402|imex:IM-8674-2|dip:DIP-57413E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 psi-mi:"MI:0465"(dip) crc64:D3B0DCBE8A580B4E crc64:34E4CDF9DE9C1824 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V61 uniprotkb:Q79V60 intact:EBI-7570699|intact:MINT-5224299|uniprotkb:Q8RR34|ensemblbacteria:BAC08034 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaib_theeb(display_long)|uniprotkb:kaiB(gene name)|psi-mi:kaiB(display_short)|uniprotkb:tlr0482(locus name) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0410"(3D electron microscopy) Mori et al. (2007) pubmed:17388688|doi:10.1371/journal.pbio.0050093|imex:IM-8674 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628419|imex:IM-8674-1|dip:DIP-57414E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_011056333.1|mint:Q79V61|refseq:NP_681272.1|ensemblbacteria:BAC08034(gene)|ensemblbacteria:BAC08034(transcript)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042326"(negative regulation of phosphorylation)|interpro:IPR013474(Circadian clock protein KaiB)|interpro:IPR036249|interpro:IPR039022|rcsb pdb:1VGL|rcsb pdb:2QKE|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:5JYT|rcsb pdb:5JYV|interpro:IPR011649(KaiB)|dip:DIP-29356N refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 psi-mi:"MI:0465"(dip) crc64:BC6B71EFBE6254E3|comment:mint|function:Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of kaiC. It has no effect on kaiC by itself, but instead needs the presence of both kaiA and kaiC, suggesting that it acts by antagonizing the interaction between kaiA and kaiC crc64:34E4CDF9DE9C1824 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:c4FTkp1XxfvbyRhMGe2Mh+zZJaU197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rigid:VlmjpCA25QymY4/4Txtig6PJT0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V60 uniprotkb:Q79V60 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0276"(blue native page) Mori et al. (2007) pubmed:17388688|doi:10.1371/journal.pbio.0050093|imex:IM-8674 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628436|imex:IM-8674-4|dip:DIP-57412E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 psi-mi:"MI:0465"(dip) crc64:34E4CDF9DE9C1824 crc64:34E4CDF9DE9C1824 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rigid:J34Cs6aVH71mufKg+r4ucWerICo false - - - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)