#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99259 uniprotkb:Q99259 intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1 intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1 psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym) psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fenalti et al. (2007) pubmed:17384644|doi:10.1038/nsmb1228|imex:IM-8636 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628339|imex:IM-8636-2|dip:DIP-57365E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606 rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606 rigid:bw6HWc3QN9Lbb957KiRV7vUuTN8 false sufficient binding region:90-594 sufficient binding region:90-594 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05329 uniprotkb:Q05329 intact:EBI-9304251|uniprotkb:Q9UD87|ensembl:ENSP00000259271|ensembl:ENSP00000365437 intact:EBI-9304251|uniprotkb:Q9UD87|ensembl:ENSP00000259271|ensembl:ENSP00000365437 psi-mi:dce2_human(display_long)|uniprotkb:GAD2(gene name)|psi-mi:GAD2(display_short)|uniprotkb:GAD65(gene name synonym)|uniprotkb:65 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 65 kDa isoform(gene name synonym) psi-mi:dce2_human(display_long)|uniprotkb:GAD2(gene name)|psi-mi:GAD2(display_short)|uniprotkb:GAD65(gene name synonym)|uniprotkb:65 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 65 kDa isoform(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fenalti et al. (2007) pubmed:17384644|doi:10.1038/nsmb1228|imex:IM-8636 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15628358|imex:IM-8636-1|dip:DIP-57366E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000809.1|refseq:NP_001127838.1|dip:DIP-29293N|ensembl:ENSG00000136750(gene)|ensembl:ENST00000259271(transcript)|ensembl:ENST00000376261(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|rcsb pdb:1ES0|rcsb pdb:2OKK|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927 refseq:NP_000809.1|refseq:NP_001127838.1|dip:DIP-29293N|ensembl:ENSG00000136750(gene)|ensembl:ENST00000259271(transcript)|ensembl:ENST00000376261(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|rcsb pdb:1ES0|rcsb pdb:2OKK|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:xEdmc7ZDRQwhbLjJ4LHsC74yJhk9606 rogid:xEdmc7ZDRQwhbLjJ4LHsC74yJhk9606 rigid:tPWLWDvfRAapExVNih1G0nEfYI4 false sufficient binding region:84-585 sufficient binding region:84-585 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)