#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00254	uniprotkb:O00254	intact:EBI-1751853|uniprotkb:Q7Z3W3|uniprotkb:Q52M68|uniprotkb:B2R754|uniprotkb:B4DQ13|ensembl:ENSP00000296641	intact:EBI-1751853|uniprotkb:Q7Z3W3|uniprotkb:Q52M68|uniprotkb:B2R754|uniprotkb:B4DQ13|ensembl:ENSP00000296641	psi-mi:par3_human(display_long)|uniprotkb:F2RL2(gene name)|psi-mi:F2RL2(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:Thrombin receptor-like 2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 2(gene name synonym)	psi-mi:par3_human(display_long)|uniprotkb:F2RL2(gene name)|psi-mi:F2RL2(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:Thrombin receptor-like 2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 2(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	McLaughlin et al. (2007)	pubmed:17376866|doi:10.1073/pnas.0700763104|imex:IM-22782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15628218|imex:IM-22782-1|dip:DIP-196731E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004092.1|refseq:NP_001243495.1|dip:DIP-44337N|ensembl:ENSG00000164220(gene)|ensembl:ENST00000296641(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0009611"(response to wounding)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR003943(Protease-activated receptor 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:O00254|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926	refseq:NP_004092.1|refseq:NP_001243495.1|dip:DIP-44337N|ensembl:ENSG00000164220(gene)|ensembl:ENST00000296641(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0009611"(response to wounding)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR003943(Protease-activated receptor 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:O00254|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:IaQ9JZBcSATjZ9nsKn3wwnHBICo9606	rogid:IaQ9JZBcSATjZ9nsKn3wwnHBICo9606	rigid:xVZjhdr+7DFsKHtJXcc/gRdG+2g	false	renilla luciferase protein tag:c-c	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25116	uniprotkb:P25116	intact:EBI-2803960|ensembl:ENSP00000321326|uniprotkb:Q53XV0|uniprotkb:Q9BUN4|uniprotkb:Q96RF7	intact:EBI-2803960|ensembl:ENSP00000321326|uniprotkb:Q53XV0|uniprotkb:Q9BUN4|uniprotkb:Q96RF7	psi-mi:par1_human(display_long)|uniprotkb:CF2R(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:TR(gene name synonym)|uniprotkb:Coagulation factor II receptor(gene name synonym)|uniprotkb:Thrombin receptor(gene name synonym)|uniprotkb:F2R(gene name)|psi-mi:F2R(display_short)	psi-mi:par1_human(display_long)|uniprotkb:CF2R(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:TR(gene name synonym)|uniprotkb:Coagulation factor II receptor(gene name synonym)|uniprotkb:Thrombin receptor(gene name synonym)|uniprotkb:F2R(gene name)|psi-mi:F2R(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	McLaughlin et al. (2007)	pubmed:17376866|doi:10.1073/pnas.0700763104|imex:IM-22782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15628239|imex:IM-22782-2|dip:DIP-196729E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181104(gene)|ensembl:ENST00000319211(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|refseq:NP_001983.2|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:1900134"(negative regulation of renin secretion into blood stream)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000935(Thrombin receptor)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|rcsb pdb:3HKI|rcsb pdb:3HKJ|rcsb pdb:3LU9|rcsb pdb:3VW7|reactome:R-HSA-140875|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926|rcsb pdb:1NRR|rcsb pdb:3BEF|refseq:NP_001298242.1|dip:DIP-29703N	ensembl:ENSG00000181104(gene)|ensembl:ENST00000319211(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|refseq:NP_001983.2|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:1900134"(negative regulation of renin secretion into blood stream)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000935(Thrombin receptor)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|rcsb pdb:3HKI|rcsb pdb:3HKJ|rcsb pdb:3LU9|rcsb pdb:3VW7|reactome:R-HSA-140875|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926|rcsb pdb:1NRR|rcsb pdb:3BEF|refseq:NP_001298242.1|dip:DIP-29703N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:XDyq4uaI8bttpcddguVYWbFJ9PA9606	rogid:XDyq4uaI8bttpcddguVYWbFJ9PA9606	rigid:OjpclUqjQVIC2Y7p4Iyeo5YJUCk	false	green fluorescent protein tag:c-c	renilla luciferase protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00254	uniprotkb:P25116	intact:EBI-1751853|uniprotkb:Q7Z3W3|uniprotkb:Q52M68|uniprotkb:B2R754|uniprotkb:B4DQ13|ensembl:ENSP00000296641	intact:EBI-2803960|ensembl:ENSP00000321326|uniprotkb:Q53XV0|uniprotkb:Q9BUN4|uniprotkb:Q96RF7	psi-mi:par3_human(display_long)|uniprotkb:F2RL2(gene name)|psi-mi:F2RL2(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:Thrombin receptor-like 2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 2(gene name synonym)	psi-mi:par1_human(display_long)|uniprotkb:CF2R(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:TR(gene name synonym)|uniprotkb:Coagulation factor II receptor(gene name synonym)|uniprotkb:Thrombin receptor(gene name synonym)|uniprotkb:F2R(gene name)|psi-mi:F2R(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	McLaughlin et al. (2007)	pubmed:17376866|doi:10.1073/pnas.0700763104|imex:IM-22782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15628260|imex:IM-22782-3|dip:DIP-196730E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004092.1|refseq:NP_001243495.1|dip:DIP-44337N|ensembl:ENSG00000164220(gene)|ensembl:ENST00000296641(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0009611"(response to wounding)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR003943(Protease-activated receptor 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:O00254|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926	ensembl:ENSG00000181104(gene)|ensembl:ENST00000319211(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|refseq:NP_001983.2|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:1900134"(negative regulation of renin secretion into blood stream)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000935(Thrombin receptor)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|rcsb pdb:3HKI|rcsb pdb:3HKJ|rcsb pdb:3LU9|rcsb pdb:3VW7|reactome:R-HSA-140875|reactome:R-HSA-375276|reactome:R-HSA-416476|reactome:R-HSA-456926|rcsb pdb:1NRR|rcsb pdb:3BEF|refseq:NP_001298242.1|dip:DIP-29703N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:IaQ9JZBcSATjZ9nsKn3wwnHBICo9606	rogid:XDyq4uaI8bttpcddguVYWbFJ9PA9606	rigid:YzotMyy1tBPQczgPFslejROtEF0	false	green fluorescent protein tag:c-c	renilla luciferase protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)