#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P29466	uniprotkb:P58753-2	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	intact:EBI-528654|ensembl:ENSP00000376445	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:p58753-2(display_long)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:MyD88 adapter-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627613|imex:IM-22756-1|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	intact:EBI-528644(tirap_human)|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392678(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:gcFbrK23U/GvAm2QoMAqQYuo3RM9606	rigid:jcC6n23vt6auyrMg5CryqgKM2vs	false	-	sufficient binding region:72-235	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58753	uniprotkb:P29466	intact:EBI-528644|uniprotkb:Q8N5E5|uniprotkb:B3KW65|uniprotkb:Q56UI0|uniprotkb:Q56UH9|ensembl:ENSP00000376446|ensembl:ENSP00000376447|ensembl:ENSP00000436967	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	psi-mi:tirap_human(display_long)|uniprotkb:MyD88 adapter-like protein(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627632|imex:IM-22756-2|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001305705.1|refseq:NP_001305706.1|refseq:NP_001034750.1|refseq:NP_683708.1|refseq:XP_005271456.2|refseq:XP_011540878.1|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392679(transcript)|ensembl:ENST00000392680(transcript)|ensembl:ENST00000479770(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032738"(positive regulation of interleukin-15 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0035665"(TIRAP-dependent toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR017279(Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap)|interpro:IPR035897|mint:P58753|rcsb pdb:2NDH|rcsb pdb:2Y92|rcsb pdb:3UB2|rcsb pdb:3UB3|rcsb pdb:3UB4|rcsb pdb:4FZ5|rcsb pdb:4LQD|rcsb pdb:5T7Q|rcsb pdb:5UZB|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|refseq:XP_016872651.1|dip:DIP-33489N	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:UmeekccCTOn8783GJqByIj+JIDE9606	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rigid:VuAh7g/0vl215NxcNX0XRZ4+pd0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29466	uniprotkb:P58753-2	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	intact:EBI-528654|ensembl:ENSP00000376445	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:p58753-2(display_long)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:MyD88 adapter-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627649|imex:IM-22756-3|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	intact:EBI-528644(tirap_human)|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392678(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:gcFbrK23U/GvAm2QoMAqQYuo3RM9606	rigid:jcC6n23vt6auyrMg5CryqgKM2vs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29466	uniprotkb:P58753-2	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	intact:EBI-528654|ensembl:ENSP00000376445	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:p58753-2(display_long)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:MyD88 adapter-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627666|imex:IM-22756-4|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	intact:EBI-528644(tirap_human)|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392678(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/14	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:gcFbrK23U/GvAm2QoMAqQYuo3RM9606	rigid:jcC6n23vt6auyrMg5CryqgKM2vs	false	au1 tag:c-c	sufficient binding region:72-235|ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29466	uniprotkb:P58753-2	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	intact:EBI-528654|ensembl:ENSP00000376445	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:p58753-2(display_long)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:MyD88 adapter-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627690|imex:IM-22756-5|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	intact:EBI-528644(tirap_human)|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392678(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/14	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:gcFbrK23U/GvAm2QoMAqQYuo3RM9606	rigid:jcC6n23vt6auyrMg5CryqgKM2vs	false	au1 tag:c-c	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29466	uniprotkb:P58753-2	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076|ensembl:ENSP00000433138	intact:EBI-528654|ensembl:ENSP00000376445	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:p58753-2(display_long)|uniprotkb:TIRAP(gene name)|psi-mi:TIRAP(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:Adaptor protein Wyatt(gene name synonym)|uniprotkb:MyD88 adapter-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Miggin et al. (2007)	pubmed:17360653|doi:10.1073/pnas.0608100104|imex:IM-22756	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627712|imex:IM-22756-6|dip:DIP-196673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|dip:DIP-175N|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|ensembl:ENSG00000137752(gene)|ensembl:ENST00000436863(transcript)|ensembl:ENST00000533400(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7	intact:EBI-528644(tirap_human)|ensembl:ENSG00000150455(gene)|ensembl:ENST00000392678(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/14	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:gcFbrK23U/GvAm2QoMAqQYuo3RM9606	rigid:jcC6n23vt6auyrMg5CryqgKM2vs	false	glutathione s tranferase tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)