#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06851	uniprotkb:P51584	intact:EBI-687595|uniprotkb:A3DJZ4|ensemblbacteria:ABN54273	intact:EBI-1037473	psi-mi:cipa_acet2(display_long)|uniprotkb:Cellulosomal glycoprotein S1/SL(gene name synonym)|uniprotkb:Cellulose-integrating protein A(gene name synonym)|uniprotkb:Cohesin(gene name synonym)|uniprotkb:cipA(gene name)|psi-mi:cipA(display_short)|uniprotkb:Cthe_3077(locus name)	psi-mi:xyny_aceth(display_long)|uniprotkb:xynY(gene name)|psi-mi:xynY(display_short)|uniprotkb:1,4-beta-D-xylan xylanohydrolase Y(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Carvalho et al. (2007)	pubmed:17360613|doi:10.1073/pnas.0611173104|imex:IM-22752	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:1515(clotm)|taxid:1515(Clostridium thermocellum)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627398|imex:IM-22752-1|dip:DIP-79415E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_020458017.1|dip:DIP-42322N|ensemblbacteria:ABN54273(transcript)|ensemblbacteria:Cthe_3077(gene)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005576"(extracellular region)|go:"GO:0030245"(cellulose catabolic process)|go:"GO:0030248"(cellulose binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR001956(Bacterial type 3a, cellulose-binding)|interpro:IPR002102(Cellulosome anchoring protein, cohesin region)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR008965(Carbohydrate-binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR018247|interpro:IPR036439|interpro:IPR036966|rcsb pdb:1ANU|rcsb pdb:1AOH|rcsb pdb:1NBC|rcsb pdb:1OHZ|rcsb pdb:2B59|rcsb pdb:2CCL|rcsb pdb:3KCP|rcsb pdb:4B9F|rcsb pdb:5G5D	go:"GO:0031176"(endo-1,4-beta-xylanase activity)|go:"GO:0043263"(cellulosome)|go:"GO:0045493"(xylan catabolic process)|interpro:IPR000801(Putative esterase)|interpro:IPR001000(Glycoside hydrolase, family 10)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR003305(Carbohydrate-binding, CenC-like)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018247|interpro:IPR029058|interpro:IPR031158|interpro:IPR036439|interpro:IPR044846|rcsb pdb:1DYO|rcsb pdb:1GKK|rcsb pdb:1GKL|rcsb pdb:1H6X|rcsb pdb:1H6Y|rcsb pdb:1OHZ|rcsb pdb:1WB4|rcsb pdb:1WB5|rcsb pdb:1WB6|rcsb pdb:2CCL|rcsb pdb:2W5F|rcsb pdb:2WYS|rcsb pdb:2WZE|rcsb pdb:3ZI7|rcsb pdb:4BAG|rcsb pdb:4H35|rcsb pdb:5FXM|rcsb pdb:6FJ4|rcsb pdb:6Y8G|interpro:IPR008979(Galactose-binding like)|dip:DIP-35413N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:0WgTh7LK2l9tMgiRUWeXKj+SkW0203119	rogid:Rsx/MjpPlqW5fbPW44re9YOgHpI1515	rigid:+Q0PMBn0SUMkEt7BcwyEVV7bVJI	false	sufficient binding region:181-328	sufficient binding region:730-791	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06851	uniprotkb:P51584	intact:EBI-687595|uniprotkb:A3DJZ4|ensemblbacteria:ABN54273	intact:EBI-1037473	psi-mi:cipa_acet2(display_long)|uniprotkb:Cellulosomal glycoprotein S1/SL(gene name synonym)|uniprotkb:Cellulose-integrating protein A(gene name synonym)|uniprotkb:Cohesin(gene name synonym)|uniprotkb:cipA(gene name)|psi-mi:cipA(display_short)|uniprotkb:Cthe_3077(locus name)	psi-mi:xyny_aceth(display_long)|uniprotkb:xynY(gene name)|psi-mi:xynY(display_short)|uniprotkb:1,4-beta-D-xylan xylanohydrolase Y(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Carvalho et al. (2007)	pubmed:17360613|doi:10.1073/pnas.0611173104|imex:IM-22752	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:1515(clotm)|taxid:1515(Clostridium thermocellum)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627442|imex:IM-22752-3|dip:DIP-79415E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_020458017.1|dip:DIP-42322N|ensemblbacteria:ABN54273(transcript)|ensemblbacteria:Cthe_3077(gene)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005576"(extracellular region)|go:"GO:0030245"(cellulose catabolic process)|go:"GO:0030248"(cellulose binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR001956(Bacterial type 3a, cellulose-binding)|interpro:IPR002102(Cellulosome anchoring protein, cohesin region)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR008965(Carbohydrate-binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR018247|interpro:IPR036439|interpro:IPR036966|rcsb pdb:1ANU|rcsb pdb:1AOH|rcsb pdb:1NBC|rcsb pdb:1OHZ|rcsb pdb:2B59|rcsb pdb:2CCL|rcsb pdb:3KCP|rcsb pdb:4B9F|rcsb pdb:5G5D	go:"GO:0031176"(endo-1,4-beta-xylanase activity)|go:"GO:0043263"(cellulosome)|go:"GO:0045493"(xylan catabolic process)|interpro:IPR000801(Putative esterase)|interpro:IPR001000(Glycoside hydrolase, family 10)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR003305(Carbohydrate-binding, CenC-like)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018247|interpro:IPR029058|interpro:IPR031158|interpro:IPR036439|interpro:IPR044846|rcsb pdb:1DYO|rcsb pdb:1GKK|rcsb pdb:1GKL|rcsb pdb:1H6X|rcsb pdb:1H6Y|rcsb pdb:1OHZ|rcsb pdb:1WB4|rcsb pdb:1WB5|rcsb pdb:1WB6|rcsb pdb:2CCL|rcsb pdb:2W5F|rcsb pdb:2WYS|rcsb pdb:2WZE|rcsb pdb:3ZI7|rcsb pdb:4BAG|rcsb pdb:4H35|rcsb pdb:5FXM|rcsb pdb:6FJ4|rcsb pdb:6Y8G|interpro:IPR008979(Galactose-binding like)|dip:DIP-35413N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:0WgTh7LK2l9tMgiRUWeXKj+SkW0203119	rogid:Rsx/MjpPlqW5fbPW44re9YOgHpI1515	rigid:+Q0PMBn0SUMkEt7BcwyEVV7bVJI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06851	uniprotkb:P51584	intact:EBI-687595|uniprotkb:A3DJZ4|ensemblbacteria:ABN54273	intact:EBI-1037473	psi-mi:cipa_acet2(display_long)|uniprotkb:Cellulosomal glycoprotein S1/SL(gene name synonym)|uniprotkb:Cellulose-integrating protein A(gene name synonym)|uniprotkb:Cohesin(gene name synonym)|uniprotkb:cipA(gene name)|psi-mi:cipA(display_short)|uniprotkb:Cthe_3077(locus name)	psi-mi:xyny_aceth(display_long)|uniprotkb:xynY(gene name)|psi-mi:xynY(display_short)|uniprotkb:1,4-beta-D-xylan xylanohydrolase Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Carvalho et al. (2007)	pubmed:17360613|doi:10.1073/pnas.0611173104|imex:IM-22752	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:1515(clotm)|taxid:1515(Clostridium thermocellum)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627419|imex:IM-22752-2|dip:DIP-79415E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_020458017.1|dip:DIP-42322N|ensemblbacteria:ABN54273(transcript)|ensemblbacteria:Cthe_3077(gene)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005576"(extracellular region)|go:"GO:0030245"(cellulose catabolic process)|go:"GO:0030248"(cellulose binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR001956(Bacterial type 3a, cellulose-binding)|interpro:IPR002102(Cellulosome anchoring protein, cohesin region)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR008965(Carbohydrate-binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR018247|interpro:IPR036439|interpro:IPR036966|rcsb pdb:1ANU|rcsb pdb:1AOH|rcsb pdb:1NBC|rcsb pdb:1OHZ|rcsb pdb:2B59|rcsb pdb:2CCL|rcsb pdb:3KCP|rcsb pdb:4B9F|rcsb pdb:5G5D	go:"GO:0031176"(endo-1,4-beta-xylanase activity)|go:"GO:0043263"(cellulosome)|go:"GO:0045493"(xylan catabolic process)|interpro:IPR000801(Putative esterase)|interpro:IPR001000(Glycoside hydrolase, family 10)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR003305(Carbohydrate-binding, CenC-like)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018247|interpro:IPR029058|interpro:IPR031158|interpro:IPR036439|interpro:IPR044846|rcsb pdb:1DYO|rcsb pdb:1GKK|rcsb pdb:1GKL|rcsb pdb:1H6X|rcsb pdb:1H6Y|rcsb pdb:1OHZ|rcsb pdb:1WB4|rcsb pdb:1WB5|rcsb pdb:1WB6|rcsb pdb:2CCL|rcsb pdb:2W5F|rcsb pdb:2WYS|rcsb pdb:2WZE|rcsb pdb:3ZI7|rcsb pdb:4BAG|rcsb pdb:4H35|rcsb pdb:5FXM|rcsb pdb:6FJ4|rcsb pdb:6Y8G|interpro:IPR008979(Galactose-binding like)|dip:DIP-35413N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:0WgTh7LK2l9tMgiRUWeXKj+SkW0203119	rogid:Rsx/MjpPlqW5fbPW44re9YOgHpI1515	rigid:+Q0PMBn0SUMkEt7BcwyEVV7bVJI	false	sufficient binding region:181-328|his tag:c-c	sufficient binding region:730-791	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06851	uniprotkb:P51584	intact:EBI-687595|uniprotkb:A3DJZ4|ensemblbacteria:ABN54273	intact:EBI-1037473	psi-mi:cipa_acet2(display_long)|uniprotkb:Cellulosomal glycoprotein S1/SL(gene name synonym)|uniprotkb:Cellulose-integrating protein A(gene name synonym)|uniprotkb:Cohesin(gene name synonym)|uniprotkb:cipA(gene name)|psi-mi:cipA(display_short)|uniprotkb:Cthe_3077(locus name)	psi-mi:xyny_aceth(display_long)|uniprotkb:xynY(gene name)|psi-mi:xynY(display_short)|uniprotkb:1,4-beta-D-xylan xylanohydrolase Y(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	Carvalho et al. (2007)	pubmed:17360613|doi:10.1073/pnas.0611173104|imex:IM-22752	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:1515(clotm)|taxid:1515(Clostridium thermocellum)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15627459|imex:IM-22752-4|dip:DIP-79415E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_020458017.1|dip:DIP-42322N|ensemblbacteria:ABN54273(transcript)|ensemblbacteria:Cthe_3077(gene)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005576"(extracellular region)|go:"GO:0030245"(cellulose catabolic process)|go:"GO:0030248"(cellulose binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR001956(Bacterial type 3a, cellulose-binding)|interpro:IPR002102(Cellulosome anchoring protein, cohesin region)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR008965(Carbohydrate-binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR018247|interpro:IPR036439|interpro:IPR036966|rcsb pdb:1ANU|rcsb pdb:1AOH|rcsb pdb:1NBC|rcsb pdb:1OHZ|rcsb pdb:2B59|rcsb pdb:2CCL|rcsb pdb:3KCP|rcsb pdb:4B9F|rcsb pdb:5G5D	go:"GO:0031176"(endo-1,4-beta-xylanase activity)|go:"GO:0043263"(cellulosome)|go:"GO:0045493"(xylan catabolic process)|interpro:IPR000801(Putative esterase)|interpro:IPR001000(Glycoside hydrolase, family 10)|interpro:IPR002105(Cellulosome enzyme, dockerin type I, calcium-binding motif)|interpro:IPR003305(Carbohydrate-binding, CenC-like)|interpro:IPR016134(Cellulosome enzyme, dockerin type I)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018247|interpro:IPR029058|interpro:IPR031158|interpro:IPR036439|interpro:IPR044846|rcsb pdb:1DYO|rcsb pdb:1GKK|rcsb pdb:1GKL|rcsb pdb:1H6X|rcsb pdb:1H6Y|rcsb pdb:1OHZ|rcsb pdb:1WB4|rcsb pdb:1WB5|rcsb pdb:1WB6|rcsb pdb:2CCL|rcsb pdb:2W5F|rcsb pdb:2WYS|rcsb pdb:2WZE|rcsb pdb:3ZI7|rcsb pdb:4BAG|rcsb pdb:4H35|rcsb pdb:5FXM|rcsb pdb:6FJ4|rcsb pdb:6Y8G|interpro:IPR008979(Galactose-binding like)|dip:DIP-35413N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:0WgTh7LK2l9tMgiRUWeXKj+SkW0203119	rogid:Rsx/MjpPlqW5fbPW44re9YOgHpI1515	rigid:+Q0PMBn0SUMkEt7BcwyEVV7bVJI	false	sufficient binding region:181-328	sufficient binding region:730-791	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)