#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BZS1-2 uniprotkb:Q92993 intact:EBI-16338471|ensembl:ENSP00000365372 intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7 psi-mi:q9bzs1-2(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15626922|imex:IM-22774-1|dip:DIP-196703E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376199(transcript)|intact:EBI-983719(isoform-parent) refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/11 rogid:SJuQfinGMCK4R+BOM3vyXqDKE7M9606 rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606 rigid:ETz1dU7pdOnMmrsmpj0vTxG2ayM false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BZS1-1 uniprotkb:Q92993 intact:EBI-9695448|ensembl:ENSP00000365380 intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7 psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15626944|imex:IM-22774-2|dip:DIP-196703E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent) refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606 rigid:nRmDimRSh+CG0wHuQG/0MwxQ0kM false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZS1-2 uniprotkb:Q8WUI4 intact:EBI-16338471|ensembl:ENSP00000365372 intact:EBI-1048378|uniprotkb:Q7Z5I1|uniprotkb:Q96K01|uniprotkb:Q9BR73|uniprotkb:Q9H7L0|uniprotkb:Q9NW41|uniprotkb:Q9NWA9|uniprotkb:Q9NYK9|uniprotkb:Q9UFU7|uniprotkb:B3KY08|uniprotkb:B4DWI0|uniprotkb:B4E0Q5|uniprotkb:Q6P1W9|uniprotkb:Q6W9G7|uniprotkb:Q7Z4K2|ensembl:ENSP00000404394 psi-mi:q9bzs1-2(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:hdac7_human(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:HDAC7(gene name)|psi-mi:HDAC7(display_short)|uniprotkb:HDAC7A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15626966|imex:IM-22774-3|dip:DIP-196704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376199(transcript)|intact:EBI-983719(isoform-parent) refseq:XP_011536783.1|refseq:XP_011536784.1|refseq:NP_001295019.1|refseq:NP_001091886.1|refseq:NP_056216.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|ensembl:ENSG00000061273(gene)|ensembl:ENST00000427332(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR023801|interpro:IPR037138|mint:Q8WUI4|rcsb pdb:3C0Y|rcsb pdb:3C0Z|rcsb pdb:3C10|rcsb pdb:3ZNR|rcsb pdb:3ZNS|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3108214|reactome:R-HSA-350054|reactome:R-HSA-8943724|dip:DIP-29860N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/11 rogid:SJuQfinGMCK4R+BOM3vyXqDKE7M9606 rogid:lRG/KaW9IIP1O9X26GT+ho94JDg9606 rigid:1swtze0yVUssxmrfU5Ef0CxYQzg false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKV0 uniprotkb:Q9BZS1 intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749|ensembl:ENSP00000410337 intact:EBI-983719|uniprotkb:O60827|uniprotkb:Q14DD8|intact:EBI-28970697|ensembl:ENSP00000365380|uniprotkb:Q4ZH51|uniprotkb:A5HJT1|uniprotkb:B7ZLG0|uniprotkb:B9UN80 psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym) psi-mi:foxp3_human(display_long)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15626988|imex:IM-22774-4|dip:DIP-196705E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308818.1|ensembl:ENST00000441542|ensembl:ENSP00000408617|ensembl:ENST00000456174|ensembl:ENSP00000388568|ensembl:ENST00000524023|ensembl:ENSP00000430036|ensembl:ENST00000401921|ensembl:ENSP00000383912|ensembl:ENST00000405010|ensembl:ENSP00000384382|ensembl:ENST00000406451|ensembl:ENSP00000384657|ensembl:ENST00000417496|ensembl:ENSP00000401669|ensembl:ENST00000428307|ensembl:ENSP00000395655|ensembl:ENSP00000410337|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|dip:DIP-39904N|ensembl:ENSG00000048052(gene)|ensembl:ENST00000432645(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|mint:Q9UKV0|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054 ensembl:ENST00000376199|ensembl:ENSP00000365372|ensembl:ENSP00000365380|ensembl:ENST00000518685|ensembl:ENSP00000428952|ensembl:ENST00000557224|ensembl:ENSP00000451208|ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QRF|rcsb pdb:4WK8|reactome:R-HSA-8877330|reactome:R-HSA-8939256|dip:DIP-36584N|refseq:NP_001107849.1|refseq:NP_054728.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rigid:hCo2KIldoLVwBGrd3Rq40lb9740 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZS1-1 uniprotkb:Q8WUI4 intact:EBI-9695448|ensembl:ENSP00000365380 intact:EBI-1048378|uniprotkb:Q7Z5I1|uniprotkb:Q96K01|uniprotkb:Q9BR73|uniprotkb:Q9H7L0|uniprotkb:Q9NW41|uniprotkb:Q9NWA9|uniprotkb:Q9NYK9|uniprotkb:Q9UFU7|uniprotkb:B3KY08|uniprotkb:B4DWI0|uniprotkb:B4E0Q5|uniprotkb:Q6P1W9|uniprotkb:Q6W9G7|uniprotkb:Q7Z4K2|ensembl:ENSP00000404394 psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:hdac7_human(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:HDAC7(gene name)|psi-mi:HDAC7(display_short)|uniprotkb:HDAC7A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627005|imex:IM-22774-5|dip:DIP-196704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent) refseq:XP_011536783.1|refseq:XP_011536784.1|refseq:NP_001295019.1|refseq:NP_001091886.1|refseq:NP_056216.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|ensembl:ENSG00000061273(gene)|ensembl:ENST00000427332(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR023801|interpro:IPR037138|mint:Q8WUI4|rcsb pdb:3C0Y|rcsb pdb:3C0Z|rcsb pdb:3C10|rcsb pdb:3ZNR|rcsb pdb:3ZNS|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3108214|reactome:R-HSA-350054|reactome:R-HSA-8943724|dip:DIP-29860N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rogid:lRG/KaW9IIP1O9X26GT+ho94JDg9606 rigid:YSc4ckVTCruadyBZQ28vJ6vDB3U false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUI4 uniprotkb:Q9BZS1 intact:EBI-1048378|uniprotkb:Q7Z5I1|uniprotkb:Q96K01|uniprotkb:Q9BR73|uniprotkb:Q9H7L0|uniprotkb:Q9NW41|uniprotkb:Q9NWA9|uniprotkb:Q9NYK9|uniprotkb:Q9UFU7|uniprotkb:B3KY08|uniprotkb:B4DWI0|uniprotkb:B4E0Q5|uniprotkb:Q6P1W9|uniprotkb:Q6W9G7|uniprotkb:Q7Z4K2|ensembl:ENSP00000404394 intact:EBI-983719|uniprotkb:O60827|uniprotkb:Q14DD8|intact:EBI-28970697|ensembl:ENSP00000365380|uniprotkb:Q4ZH51|uniprotkb:A5HJT1|uniprotkb:B7ZLG0|uniprotkb:B9UN80 psi-mi:hdac7_human(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:HDAC7(gene name)|psi-mi:HDAC7(display_short)|uniprotkb:HDAC7A(gene name synonym) psi-mi:foxp3_human(display_long)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627027|imex:IM-22774-6|dip:DIP-196704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536783.1|refseq:XP_011536784.1|refseq:NP_001295019.1|refseq:NP_001091886.1|refseq:NP_056216.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|ensembl:ENSG00000061273(gene)|ensembl:ENST00000427332(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR023801|interpro:IPR037138|mint:Q8WUI4|rcsb pdb:3C0Y|rcsb pdb:3C0Z|rcsb pdb:3C10|rcsb pdb:3ZNR|rcsb pdb:3ZNS|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3108214|reactome:R-HSA-350054|reactome:R-HSA-8943724|dip:DIP-29860N ensembl:ENST00000376199|ensembl:ENSP00000365372|ensembl:ENSP00000365380|ensembl:ENST00000518685|ensembl:ENSP00000428952|ensembl:ENST00000557224|ensembl:ENSP00000451208|ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QRF|rcsb pdb:4WK8|reactome:R-HSA-8877330|reactome:R-HSA-8939256|dip:DIP-36584N|refseq:NP_001107849.1|refseq:NP_054728.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:lRG/KaW9IIP1O9X26GT+ho94JDg9606 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rigid:YSc4ckVTCruadyBZQ28vJ6vDB3U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZS1-2 uniprotkb:Q8WUI4 intact:EBI-16338471|ensembl:ENSP00000365372 intact:EBI-1048378|uniprotkb:Q7Z5I1|uniprotkb:Q96K01|uniprotkb:Q9BR73|uniprotkb:Q9H7L0|uniprotkb:Q9NW41|uniprotkb:Q9NWA9|uniprotkb:Q9NYK9|uniprotkb:Q9UFU7|uniprotkb:B3KY08|uniprotkb:B4DWI0|uniprotkb:B4E0Q5|uniprotkb:Q6P1W9|uniprotkb:Q6W9G7|uniprotkb:Q7Z4K2|ensembl:ENSP00000404394 psi-mi:q9bzs1-2(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:hdac7_human(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:HDAC7(gene name)|psi-mi:HDAC7(display_short)|uniprotkb:HDAC7A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627044|imex:IM-22774-7|dip:DIP-196704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376199(transcript)|intact:EBI-983719(isoform-parent) refseq:XP_011536783.1|refseq:XP_011536784.1|refseq:NP_001295019.1|refseq:NP_001091886.1|refseq:NP_056216.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|ensembl:ENSG00000061273(gene)|ensembl:ENST00000427332(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR023801|interpro:IPR037138|mint:Q8WUI4|rcsb pdb:3C0Y|rcsb pdb:3C0Z|rcsb pdb:3C10|rcsb pdb:3ZNR|rcsb pdb:3ZNS|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3108214|reactome:R-HSA-350054|reactome:R-HSA-8943724|dip:DIP-29860N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/11 rogid:SJuQfinGMCK4R+BOM3vyXqDKE7M9606 rogid:lRG/KaW9IIP1O9X26GT+ho94JDg9606 rigid:1swtze0yVUssxmrfU5Ef0CxYQzg false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UKV0 uniprotkb:Q9BZS1-1 intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749|ensembl:ENSP00000410337 intact:EBI-9695448|ensembl:ENSP00000365380 psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym) psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627066|imex:IM-22774-8|dip:DIP-196705E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308818.1|ensembl:ENST00000441542|ensembl:ENSP00000408617|ensembl:ENST00000456174|ensembl:ENSP00000388568|ensembl:ENST00000524023|ensembl:ENSP00000430036|ensembl:ENST00000401921|ensembl:ENSP00000383912|ensembl:ENST00000405010|ensembl:ENSP00000384382|ensembl:ENST00000406451|ensembl:ENSP00000384657|ensembl:ENST00000417496|ensembl:ENSP00000401669|ensembl:ENST00000428307|ensembl:ENSP00000395655|ensembl:ENSP00000410337|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|dip:DIP-39904N|ensembl:ENSG00000048052(gene)|ensembl:ENST00000432645(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|mint:Q9UKV0|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054 ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rigid:hCo2KIldoLVwBGrd3Rq40lb9740 false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZS1-1 uniprotkb:Q8WUI4 intact:EBI-9695448|ensembl:ENSP00000365380 intact:EBI-1048378|uniprotkb:Q7Z5I1|uniprotkb:Q96K01|uniprotkb:Q9BR73|uniprotkb:Q9H7L0|uniprotkb:Q9NW41|uniprotkb:Q9NWA9|uniprotkb:Q9NYK9|uniprotkb:Q9UFU7|uniprotkb:B3KY08|uniprotkb:B4DWI0|uniprotkb:B4E0Q5|uniprotkb:Q6P1W9|uniprotkb:Q6W9G7|uniprotkb:Q7Z4K2|ensembl:ENSP00000404394 psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:hdac7_human(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:HDAC7(gene name)|psi-mi:HDAC7(display_short)|uniprotkb:HDAC7A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627086|imex:IM-22774-9|dip:DIP-196704E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent) refseq:XP_011536783.1|refseq:XP_011536784.1|refseq:NP_001295019.1|refseq:NP_001091886.1|refseq:NP_056216.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|ensembl:ENSG00000061273(gene)|ensembl:ENST00000427332(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR023801|interpro:IPR037138|mint:Q8WUI4|rcsb pdb:3C0Y|rcsb pdb:3C0Z|rcsb pdb:3C10|rcsb pdb:3ZNR|rcsb pdb:3ZNS|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3108214|reactome:R-HSA-350054|reactome:R-HSA-8943724|dip:DIP-29860N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rogid:lRG/KaW9IIP1O9X26GT+ho94JDg9606 rigid:YSc4ckVTCruadyBZQ28vJ6vDB3U false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BZS1-1 uniprotkb:Q92993 intact:EBI-9695448|ensembl:ENSP00000365380 intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7 psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2007) pubmed:17360565|doi:10.1073/pnas.0700298104|imex:IM-22774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15627108|imex:IM-22774-10|dip:DIP-196703E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent) refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606 rigid:nRmDimRSh+CG0wHuQG/0MwxQ0kM false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)