#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22808	uniprotkb:Q24533	intact:EBI-171341|uniprotkb:Q24589|uniprotkb:Q26436|uniprotkb:Q9UB43|uniprotkb:Q9W5F0|ensemblmetazoa:FBpp0070105	intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250	psi-mi:vnd_drome(display_long)|uniprotkb:vnd(gene name)|psi-mi:vnd(display_short)|uniprotkb:NK2(gene name synonym)|uniprotkb:CG6172(orf name)|uniprotkb:Protein ventral nervous system defective(gene name synonym)|uniprotkb:Homeobox protein NK-2(gene name synonym)	psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2007)	pubmed:17360441|doi:10.1073/pnas.0611700104|imex:IM-22764	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625911|imex:IM-22764-1|dip:DIP-196687E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476786.2|flybase:FBgn0261930|dip:DIP-60882N|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1NK2|rcsb pdb:1NK3|rcsb pdb:1QRY|rcsb pdb:1VND|ensemblmetazoa:FBgn0261930(gene)|ensemblmetazoa:FBtr0070110(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)	refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:oL3elkR7zHsn9IKVMeSVZ3IzoA07227	rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227	rigid:UhmxoBWCzjDtx3EjqCjA5UJulG0	false	sufficient binding region:1-536	sufficient binding region:1-141	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22808	uniprotkb:Q24533	intact:EBI-171341|uniprotkb:Q24589|uniprotkb:Q26436|uniprotkb:Q9UB43|uniprotkb:Q9W5F0|ensemblmetazoa:FBpp0070105	intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250	psi-mi:vnd_drome(display_long)|uniprotkb:vnd(gene name)|psi-mi:vnd(display_short)|uniprotkb:NK2(gene name synonym)|uniprotkb:CG6172(orf name)|uniprotkb:Protein ventral nervous system defective(gene name synonym)|uniprotkb:Homeobox protein NK-2(gene name synonym)	psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2007)	pubmed:17360441|doi:10.1073/pnas.0611700104|imex:IM-22764	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625932|imex:IM-22764-2|dip:DIP-196687E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476786.2|flybase:FBgn0261930|dip:DIP-60882N|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1NK2|rcsb pdb:1NK3|rcsb pdb:1QRY|rcsb pdb:1VND|ensemblmetazoa:FBgn0261930(gene)|ensemblmetazoa:FBtr0070110(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)	refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:oL3elkR7zHsn9IKVMeSVZ3IzoA07227	rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227	rigid:UhmxoBWCzjDtx3EjqCjA5UJulG0	false	-	sufficient binding region:1-141|sufficient binding region:142-382	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6IL70	uniprotkb:Q24533	intact:EBI-15625953|ensemblmetazoa:FBpp0306007	intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250	psi-mi:q6il70_drome(display_long)|uniprotkb:CG11551-RA(gene name)|psi-mi:CG11551-RA(display_short)|uniprotkb:HDC10207(orf name)	psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2007)	pubmed:17360441|doi:10.1073/pnas.0611700104|imex:IM-22764	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625968|imex:IM-22764-3|dip:DIP-196688E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0025776(gene)|ensemblmetazoa:FBtr0333875(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-60883N	refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:eJY3iFRx8cioIjQjMUDq8WZlvwU7227	rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227	rigid:6LxtSSqMNJw6SEAzajVhWDx/jvA	false	sufficient binding region:296-391|sufficient binding region:1-302	sufficient binding region:1-141	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6IL70	uniprotkb:Q24533	intact:EBI-15625953|ensemblmetazoa:FBpp0306007	intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250	psi-mi:q6il70_drome(display_long)|uniprotkb:CG11551-RA(gene name)|psi-mi:CG11551-RA(display_short)|uniprotkb:HDC10207(orf name)	psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2007)	pubmed:17360441|doi:10.1073/pnas.0611700104|imex:IM-22764	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625991|imex:IM-22764-4|dip:DIP-196688E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0025776(gene)|ensemblmetazoa:FBtr0333875(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|dip:DIP-60883N	refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:eJY3iFRx8cioIjQjMUDq8WZlvwU7227	rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227	rigid:6LxtSSqMNJw6SEAzajVhWDx/jvA	false	-	sufficient binding region:1-141	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)