#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9I9K6	uniprotkb:Q8QGV2	intact:EBI-959114	intact:EBI-15625605|uniprotkb:Q641D3	psi-mi:q9i9k6_xenla(display_long)|uniprotkb:pin1.L(gene name)|psi-mi:pin1.L(display_short)|uniprotkb:Pin1(gene name synonym)|uniprotkb:pin1(gene name synonym)|uniprotkb:XELAEV_18018988mg(orf name)	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625627|imex:IM-22761-1|dip:DIP-196682E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084236.1|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|dip:DIP-35667N|mint:Q9I9K6	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:+U9gyIQdDqGzHcjEw8wiytjTClM8355	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rigid:HM9culb8aoQkOXdVWPm3rzgnCgM	false	-	sufficient binding region:179-191|O-phospho-L-threonine:186-186	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8QGV2	uniprotkb:Q8QGV2	intact:EBI-15625605|uniprotkb:Q641D3	intact:EBI-15625605|uniprotkb:Q641D3	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625649|imex:IM-22761-2|dip:DIP-196680E	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rigid:/gkIz9npCJ7YWjleW0aQFR1E3BA	false	mutation disrupting interaction rate:277-277	mutation disrupting interaction rate:277-277	-	0	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8QGV2	uniprotkb:P13351	intact:EBI-15625605|uniprotkb:Q641D3	intact:EBI-11608179|uniprotkb:Q498K5	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:ccnb2_xenla(display_long)|uniprotkb:ccnb2(gene name)|psi-mi:ccnb2(display_short)	psi-mi:"MI:0096"(pull down)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625687|imex:IM-22761-3|dip:DIP-196681E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	refseq:NP_001081268.1|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|dip:DIP-60880N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	-	2017/08/05	2017/08/10	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rogid:or9Ka1t3wdOO7mCm2wsAWXLXOVI8355	rigid:JTlJ8kuccsdrXtIovpTnUJkMjco	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8QGV2	uniprotkb:P23437	intact:EBI-15625605|uniprotkb:Q641D3	intact:EBI-15625668|uniprotkb:Q3KPN7	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:cdk2_xenla(display_long)|uniprotkb:cdk2(gene name)|psi-mi:cdk2(display_short)|uniprotkb:eg1(gene name synonym)|uniprotkb:CDC2 homolog Eg1 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625687|imex:IM-22761-3|dip:DIP-196681E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084120.1|dip:DIP-60879N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	-	2017/08/05	2017/08/10	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rogid:rDVGYrbR6mbZqqxDwlusDAKZuX08355	rigid:JTlJ8kuccsdrXtIovpTnUJkMjco	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9I9K6	uniprotkb:Q8QGV2	intact:EBI-959114	intact:EBI-15625605|uniprotkb:Q641D3	psi-mi:q9i9k6_xenla(display_long)|uniprotkb:pin1.L(gene name)|psi-mi:pin1.L(display_short)|uniprotkb:Pin1(gene name synonym)|uniprotkb:pin1(gene name synonym)|uniprotkb:XELAEV_18018988mg(orf name)	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625707|imex:IM-22761-4|dip:DIP-196682E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001084236.1|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|dip:DIP-35667N|mint:Q9I9K6	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	-	2017/08/05	2017/08/10	rogid:+U9gyIQdDqGzHcjEw8wiytjTClM8355	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rigid:HM9culb8aoQkOXdVWPm3rzgnCgM	false	glutathione s tranferase tag:n-n	myc tag:n-n|mutation disrupting interaction strength:186-186	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QGV2	uniprotkb:Q8QGV2	intact:EBI-15625605|uniprotkb:Q641D3	intact:EBI-15625605|uniprotkb:Q641D3	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:wee1b_xenla(display_long)|uniprotkb:wee1-b(gene name)|psi-mi:wee1-b(display_short)|uniprotkb:Zygotic wee1-like protein kinase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Okamoto et al. (2007)	pubmed:17360425|doi:10.1073/pnas.0607357104|imex:IM-22761	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:1127"(putative self interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15625731|imex:IM-22761-5|dip:DIP-196680E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001084186.1|dip:DIP-60878N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rogid:BLwv67ijQeSSx12mK3a1w+cVxfs8355	rigid:39NH2mzSldhGkyNiHAQDgTRRmZY	false	sufficient binding region:242-595|glutathione s tranferase tag:n-n	sufficient binding region:1-241|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)