#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O66874 uniprotkb:O66874 intact:EBI-15625175|ensemblbacteria:AAC06835 intact:EBI-15625175|ensemblbacteria:AAC06835 psi-mi:pbpa_aquae(display_long)|uniprotkb:mrcA(gene name)|psi-mi:mrcA(display_short)|uniprotkb:ponA(gene name synonym)|uniprotkb:aq_624(locus name) psi-mi:pbpa_aquae(display_long)|uniprotkb:mrcA(gene name)|psi-mi:mrcA(display_short)|uniprotkb:ponA(gene name synonym)|uniprotkb:aq_624(locus name) psi-mi:"MI:0071"(molecular sieving) Yuan et al. (2007) pubmed:17360321|doi:10.1073/pnas.0701160104|imex:IM-22778 taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15625202|imex:IM-22778-1|dip:DIP-196722E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071555"(cell wall organization)|interpro:IPR001264(Glycosyl transferase, family 51)|ensemblbacteria:AAC06835(transcript)|ensemblbacteria:aq_624(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR023346|interpro:IPR036950|rcsb pdb:2OQO|rcsb pdb:3D3H|rcsb pdb:3NB6|rcsb pdb:3NB7|refseq:NP_213434.1|refseq:WP_010880372.1|dip:DIP-60897N go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071555"(cell wall organization)|interpro:IPR001264(Glycosyl transferase, family 51)|ensemblbacteria:AAC06835(transcript)|ensemblbacteria:aq_624(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR023346|interpro:IPR036950|rcsb pdb:2OQO|rcsb pdb:3D3H|rcsb pdb:3NB6|rcsb pdb:3NB7|refseq:NP_213434.1|refseq:WP_010880372.1|dip:DIP-60897N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:FPWcBWh4tioeyiRgYwaelVf5UnU224324 rogid:FPWcBWh4tioeyiRgYwaelVf5UnU224324 rigid:TTyMIPfBJWmSoL8bH0xxV08G1xg false sufficient binding region:29-243 sufficient binding region:29-243 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66874 uniprotkb:O66874 intact:EBI-15625175|ensemblbacteria:AAC06835 intact:EBI-15625175|ensemblbacteria:AAC06835 psi-mi:pbpa_aquae(display_long)|uniprotkb:mrcA(gene name)|psi-mi:mrcA(display_short)|uniprotkb:ponA(gene name synonym)|uniprotkb:aq_624(locus name) psi-mi:pbpa_aquae(display_long)|uniprotkb:mrcA(gene name)|psi-mi:mrcA(display_short)|uniprotkb:ponA(gene name synonym)|uniprotkb:aq_624(locus name) psi-mi:"MI:0114"(x-ray crystallography) Yuan et al. (2007) pubmed:17360321|doi:10.1073/pnas.0701160104|imex:IM-22778 taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15625221|imex:IM-22778-2|dip:DIP-196722E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071555"(cell wall organization)|interpro:IPR001264(Glycosyl transferase, family 51)|ensemblbacteria:AAC06835(transcript)|ensemblbacteria:aq_624(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR023346|interpro:IPR036950|rcsb pdb:2OQO|rcsb pdb:3D3H|rcsb pdb:3NB6|rcsb pdb:3NB7|refseq:NP_213434.1|refseq:WP_010880372.1|dip:DIP-60897N go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071555"(cell wall organization)|interpro:IPR001264(Glycosyl transferase, family 51)|ensemblbacteria:AAC06835(transcript)|ensemblbacteria:aq_624(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR023346|interpro:IPR036950|rcsb pdb:2OQO|rcsb pdb:3D3H|rcsb pdb:3NB6|rcsb pdb:3NB7|refseq:NP_213434.1|refseq:WP_010880372.1|dip:DIP-60897N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:FPWcBWh4tioeyiRgYwaelVf5UnU224324 rogid:FPWcBWh4tioeyiRgYwaelVf5UnU224324 rigid:TTyMIPfBJWmSoL8bH0xxV08G1xg false sufficient binding region:51-243 sufficient binding region:51-243 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)