#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13693 uniprotkb:Q15382 intact:EBI-1783169|uniprotkb:Q6YLS2|uniprotkb:Q7Z4J4|uniprotkb:Q96EE2|uniprotkb:Q9UC70|intact:EBI-1058458|uniprotkb:B2R7E5|intact:EBI-5772926|uniprotkb:Q8TBK7|ensembl:ENSP00000431872 intact:EBI-1055287|uniprotkb:Q53Y56|uniprotkb:Q99444|uniprotkb:B3KWN6|uniprotkb:D3DX13|ensembl:ENSP00000262187 psi-mi:tctp_human(display_long)|uniprotkb:TPT1(gene name)|psi-mi:TPT1(display_short)|uniprotkb:p23(gene name synonym)|uniprotkb:Histamine-releasing factor(gene name synonym)|uniprotkb:Fortilin(gene name synonym) psi-mi:rheb_human(display_long)|uniprotkb:Ras homolog enriched in brain(gene name synonym)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym) psi-mi:"MI:0096"(pull down) Hsu et al. (2007) pubmed:17301792|doi:10.1038/nature05528|imex:IM-21196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15623780|imex:IM-21196-2|dip:DIP-191094E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003286.1|refseq:NP_001273202.1|dip:DIP-40097N|ensembl:ENSG00000133112(gene)|ensembl:ENST00000530705(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009615"(response to virus)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P13693|rcsb pdb:1YZ1|rcsb pdb:2HR9|rcsb pdb:3EBM|rcsb pdb:4Z9V|rcsb pdb:5O9L|rcsb pdb:5O9M|rcsb pdb:6IZB|rcsb pdb:6IZE refseq:NP_005605.1|ensembl:ENSG00000106615(gene)|ensembl:ENST00000262187(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:2000074"(regulation of type B pancreatic cell development)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR037586|mint:Q15382|rcsb pdb:1XTQ|rcsb pdb:1XTR|rcsb pdb:1XTS|rcsb pdb:3SEA|rcsb pdb:3T5G|rcsb pdb:5YXH|rcsb pdb:6BCU|rcsb pdb:6BSX|rcsb pdb:6BT0|rcsb pdb:7BTA|rcsb pdb:7BTC|rcsb pdb:7BTD|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0019003"(GDP binding)|dip:DIP-42816N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:1RijAyNqyKFL9LvKa9wbYtC4fRo9606 rogid:GE8DyIWfwPVdBLbXAI3mHbo1uVs9606 rigid:VzVW3LUCsWKhRpOYQSCITGcXAYk false glutathione s tranferase tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VND8 uniprotkb:Q9VGS2 intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343 intact:EBI-100452|uniprotkb:Q49UC2|uniprotkb:Q95TW0|ensemblmetazoa:FBpp0081820|ensemblmetazoa:FBpp0312492 psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name) psi-mi:tctp_drome(display_long)|uniprotkb:CG4800(orf name)|uniprotkb:Tctp(gene name)|psi-mi:Tctp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hsu et al. (2007) pubmed:17301792|doi:10.1038/nature05528|imex:IM-21196 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15623759|imex:IM-21196-1|dip:DIP-191093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity) refseq:NP_650048.1|flybase:FBgn0037874|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|go:"GO:0005509"(calcium ion binding)|refseq:NP_001303431.1|ensemblmetazoa:FBgn0037874(gene)|ensemblmetazoa:FBtr0082344(transcript)|ensemblmetazoa:FBtr0347181(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|dip:DIP-18951N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227 rogid:WGQSHU0cVxqgcd6XnKmtsZ0jVWA7227 rigid:/k12YtFrY1LehA6no4trc8SCT6Q false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VND8 uniprotkb:Q9VGS2 intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343 intact:EBI-100452|uniprotkb:Q49UC2|uniprotkb:Q95TW0|ensemblmetazoa:FBpp0081820|ensemblmetazoa:FBpp0312492 psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name) psi-mi:tctp_drome(display_long)|uniprotkb:CG4800(orf name)|uniprotkb:Tctp(gene name)|psi-mi:Tctp(display_short) psi-mi:"MI:0096"(pull down) Hsu et al. (2007) pubmed:17301792|doi:10.1038/nature05528|imex:IM-21196 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15623818|imex:IM-21196-4|dip:DIP-191093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity) refseq:NP_650048.1|flybase:FBgn0037874|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|go:"GO:0005509"(calcium ion binding)|refseq:NP_001303431.1|ensemblmetazoa:FBgn0037874(gene)|ensemblmetazoa:FBtr0082344(transcript)|ensemblmetazoa:FBtr0347181(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|dip:DIP-18951N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227 rogid:WGQSHU0cVxqgcd6XnKmtsZ0jVWA7227 rigid:/k12YtFrY1LehA6no4trc8SCT6Q false maltose binding protein tag:n-n mutation decreasing interaction strength:12-12|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P13693 uniprotkb:Q15382 intact:EBI-1783169|uniprotkb:Q6YLS2|uniprotkb:Q7Z4J4|uniprotkb:Q96EE2|uniprotkb:Q9UC70|intact:EBI-1058458|uniprotkb:B2R7E5|intact:EBI-5772926|uniprotkb:Q8TBK7|ensembl:ENSP00000431872 intact:EBI-1055287|uniprotkb:Q53Y56|uniprotkb:Q99444|uniprotkb:B3KWN6|uniprotkb:D3DX13|ensembl:ENSP00000262187 psi-mi:tctp_human(display_long)|uniprotkb:TPT1(gene name)|psi-mi:TPT1(display_short)|uniprotkb:p23(gene name synonym)|uniprotkb:Histamine-releasing factor(gene name synonym)|uniprotkb:Fortilin(gene name synonym) psi-mi:rheb_human(display_long)|uniprotkb:Ras homolog enriched in brain(gene name synonym)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym) psi-mi:"MI:0949"(gdp/gtp exchange assay) Hsu et al. (2007) pubmed:17301792|doi:10.1038/nature05528|imex:IM-21196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15623801|imex:IM-21196-3|dip:DIP-191094E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003286.1|refseq:NP_001273202.1|dip:DIP-40097N|ensembl:ENSG00000133112(gene)|ensembl:ENST00000530705(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009615"(response to virus)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P13693|rcsb pdb:1YZ1|rcsb pdb:2HR9|rcsb pdb:3EBM|rcsb pdb:4Z9V|rcsb pdb:5O9L|rcsb pdb:5O9M|rcsb pdb:6IZB|rcsb pdb:6IZE refseq:NP_005605.1|ensembl:ENSG00000106615(gene)|ensembl:ENST00000262187(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:2000074"(regulation of type B pancreatic cell development)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR037586|mint:Q15382|rcsb pdb:1XTQ|rcsb pdb:1XTR|rcsb pdb:1XTS|rcsb pdb:3SEA|rcsb pdb:3T5G|rcsb pdb:5YXH|rcsb pdb:6BCU|rcsb pdb:6BSX|rcsb pdb:6BT0|rcsb pdb:7BTA|rcsb pdb:7BTC|rcsb pdb:7BTD|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0019003"(GDP binding)|dip:DIP-42816N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:1RijAyNqyKFL9LvKa9wbYtC4fRo9606 rogid:GE8DyIWfwPVdBLbXAI3mHbo1uVs9606 rigid:VzVW3LUCsWKhRpOYQSCITGcXAYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VND8 uniprotkb:Q9VGS2 intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343 intact:EBI-100452|uniprotkb:Q49UC2|uniprotkb:Q95TW0|ensemblmetazoa:FBpp0081820|ensemblmetazoa:FBpp0312492 psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name) psi-mi:tctp_drome(display_long)|uniprotkb:CG4800(orf name)|uniprotkb:Tctp(gene name)|psi-mi:Tctp(display_short) psi-mi:"MI:0949"(gdp/gtp exchange assay) Hsu et al. (2007) pubmed:17301792|doi:10.1038/nature05528|imex:IM-21196 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15623842|imex:IM-21196-5|dip:DIP-191093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity) refseq:NP_650048.1|flybase:FBgn0037874|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|go:"GO:0005509"(calcium ion binding)|refseq:NP_001303431.1|ensemblmetazoa:FBgn0037874(gene)|ensemblmetazoa:FBtr0082344(transcript)|ensemblmetazoa:FBtr0347181(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|dip:DIP-18951N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227 rogid:WGQSHU0cVxqgcd6XnKmtsZ0jVWA7227 rigid:/k12YtFrY1LehA6no4trc8SCT6Q false - mutation disrupting interaction strength:12-12 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)