#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28715 uniprotkb:P24522 intact:EBI-765885|uniprotkb:Q7Z2V3|uniprotkb:Q8IZL6|uniprotkb:Q8N1B7|uniprotkb:Q9HD59|uniprotkb:A6NGT4|uniprotkb:Q5JUS4|uniprotkb:Q5JUS5|uniprotkb:Q9HD60|ensembl:ENSP00000498881 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:ercc5_human(display_long)|uniprotkb:Xeroderma pigmentosum group G-complementing protein(gene name synonym)|uniprotkb:ERCC5(gene name)|psi-mi:ERCC5(display_short)|uniprotkb:XPG(gene name synonym)|uniprotkb:XPGC(gene name synonym)|uniprotkb:ERCM2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-G cells(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0096"(pull down) Barreto et al. (2007) pubmed:17268471|doi:10.1038/nature05515|imex:IM-21193 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15620691|imex:IM-21193-1|dip:DIP-191091E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000114.2|dip:DIP-750N|ensembl:ENSG00000134899(gene)|ensembl:ENST00000652225(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010225"(response to UV-C)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR001044(Xeroderma pigmentosum group G protein)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279|rcsb pdb:5EKF|rcsb pdb:5EKG|rcsb pdb:6TUR|rcsb pdb:6TUS|rcsb pdb:6TUW|rcsb pdb:6TUX|rcsb pdb:6VBH|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:lOswBNjQY5IO5v7jo6QvtNh/6XI9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rigid:pesKEr2ql2mxuKdxdX6HQrVMgOA false 35s radiolabel:?-? his tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P28715 uniprotkb:P24522 intact:EBI-765885|uniprotkb:Q7Z2V3|uniprotkb:Q8IZL6|uniprotkb:Q8N1B7|uniprotkb:Q9HD59|uniprotkb:A6NGT4|uniprotkb:Q5JUS4|uniprotkb:Q5JUS5|uniprotkb:Q9HD60|ensembl:ENSP00000498881 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:ercc5_human(display_long)|uniprotkb:Xeroderma pigmentosum group G-complementing protein(gene name synonym)|uniprotkb:ERCC5(gene name)|psi-mi:ERCC5(display_short)|uniprotkb:XPG(gene name synonym)|uniprotkb:XPGC(gene name synonym)|uniprotkb:ERCM2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-G cells(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Barreto et al. (2007) pubmed:17268471|doi:10.1038/nature05515|imex:IM-21193 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15620712|imex:IM-21193-2|dip:DIP-191091E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000114.2|dip:DIP-750N|ensembl:ENSG00000134899(gene)|ensembl:ENST00000652225(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010225"(response to UV-C)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR001044(Xeroderma pigmentosum group G protein)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279|rcsb pdb:5EKF|rcsb pdb:5EKG|rcsb pdb:6TUR|rcsb pdb:6TUS|rcsb pdb:6TUW|rcsb pdb:6TUX|rcsb pdb:6VBH|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:lOswBNjQY5IO5v7jo6QvtNh/6XI9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rigid:pesKEr2ql2mxuKdxdX6HQrVMgOA false - flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)