#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P41695	uniprotkb:P26449	intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short)	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15618943|imex:IM-22500-1|dip:DIP-2519E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	psi-mi:"MI:0465"(dip)	crc64:6D76FC980775D3F9	crc64:0BDFB8697935BCEB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rigid:uPMpRTuexHAEMob+3KmUDHDObUs	false	sufficient binding region:315-356	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26449	uniprotkb:P47074	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15618962|imex:IM-22500-2|dip:DIP-9853E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N	psi-mi:"MI:0465"(dip)	crc64:0BDFB8697935BCEB	crc64:36550249D81BB6D1	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rogid:lyE7pycs775JBy2fvm2J861azlg559292	rigid:K7nkUD+vnRUMK4rkfjY9FQtfdpQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41695	uniprotkb:P26449	intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short)	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15618979|imex:IM-22500-3|dip:DIP-2519E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	psi-mi:"MI:0465"(dip)	crc64:6D76FC980775D3F9	crc64:0BDFB8697935BCEB	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rigid:uPMpRTuexHAEMob+3KmUDHDObUs	false	sufficient binding region:315-356	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26449	uniprotkb:P47074	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15618998|imex:IM-22500-4|dip:DIP-9853E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N	psi-mi:"MI:0465"(dip)	crc64:0BDFB8697935BCEB	crc64:36550249D81BB6D1	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rogid:lyE7pycs775JBy2fvm2J861azlg559292	rigid:K7nkUD+vnRUMK4rkfjY9FQtfdpQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26449	uniprotkb:P47074	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15619016|imex:IM-22500-5|dip:DIP-9853E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N	psi-mi:"MI:0465"(dip)	crc64:0BDFB8697935BCEB	crc64:36550249D81BB6D1	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rogid:lyE7pycs775JBy2fvm2J861azlg559292	rigid:K7nkUD+vnRUMK4rkfjY9FQtfdpQ	false	-	sufficient binding region:354-401	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26449	uniprotkb:P47074	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15619035|imex:IM-22500-6|dip:DIP-9853E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N	psi-mi:"MI:0465"(dip)	crc64:0BDFB8697935BCEB	crc64:36550249D81BB6D1	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rogid:lyE7pycs775JBy2fvm2J861azlg559292	rigid:K7nkUD+vnRUMK4rkfjY9FQtfdpQ	false	mutation disrupting interaction strength:197-197	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26449	uniprotkb:P47074	intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W	intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4	psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Larsen et al. (2007)	pubmed:17227844|doi:10.1073/pnas.0610358104|imex:IM-22500	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15619055|imex:IM-22500-7|dip:DIP-9853E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0	sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N	psi-mi:"MI:0465"(dip)	crc64:0BDFB8697935BCEB	crc64:36550249D81BB6D1	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292	rogid:lyE7pycs775JBy2fvm2J861azlg559292	rigid:K7nkUD+vnRUMK4rkfjY9FQtfdpQ	false	-	sufficient binding region:354-401	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)